Experiment description of studies that identified CCNL2 in sEVs

1 Experiment ID 237 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocytes Sample name MIHA Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RNA Sequencing

Protein-protein interactions for CCNL2

Protein Interactor ExoCarta ID Identification method PubMed Species 1 GATAD2A 54815 Affinity Capture-MS Homo sapiens 2 ULBP3 79465 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 3 PTPRG 5793 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 4 GNAZ 2781 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 5 KIF22   Affinity Capture-MS Homo sapiens 6 CSNK2B 1460 Affinity Capture-MS Homo sapiens 7 PYGB 5834 Affinity Capture-MS Homo sapiens 8 ZBTB43   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 9 Oxnad1   Affinity Capture-MS Mus musculus 10 EHD1 10938 Affinity Capture-MS Homo sapiens 11 Racgap1 26934 Affinity Capture-MS Mus musculus 12 GNB4 59345 Affinity Capture-MS Homo sapiens 13 BTNL9   Affinity Capture-MS Homo sapiens 14 IREB2 3658 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 15 ZCRB1   Affinity Capture-MS Homo sapiens 16 NSDHL 50814 Affinity Capture-MS Homo sapiens 17 FIGLA   Affinity Capture-MS Homo sapiens 18 Bcas2   Affinity Capture-MS Mus musculus 19 SAP30BP   Affinity Capture-MS Homo sapiens 20 TRIM41 90933 Two-hybrid Homo sapiens 21 ANAPC15   Affinity Capture-MS Homo sapiens 22 MEX3A   Affinity Capture-RNA Homo sapiens 23 JMJD6 23210 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 24 PIH1D2   Two-hybrid Homo sapiens 25 PRKACG   Affinity Capture-MS Homo sapiens 26 MDFI   Two-hybrid Homo sapiens 27 GNAQ 2776 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 28 EMD 2010 Two-hybrid Homo sapiens 29 CSNK2A1 1457 Affinity Capture-MS Homo sapiens 30 SMPDL3B 27293 Affinity Capture-MS Homo sapiens 31 HDAC1 3065 Affinity Capture-MS Homo sapiens 32 FAM90A1   Two-hybrid Homo sapiens 33 GAP43   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 34 SNX6 58533 Affinity Capture-MS Homo sapiens 35 MAGEA9   Affinity Capture-MS Homo sapiens 36 POLR2A 5430 Affinity Capture-Western Homo sapiens 37 LYN 4067 Affinity Capture-MS Homo sapiens 38 OCIAD1 54940 Affinity Capture-MS Homo sapiens 39 IRF2BP1 26145 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 40 CCNY 219771 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 41 DHX40   Affinity Capture-MS Homo sapiens 42 JAK3 3718 Affinity Capture-MS Homo sapiens 43 ABCF2 10061 Affinity Capture-MS Homo sapiens 44 ACACA 31 Positive Genetic Homo sapiens 45 GNA11 2767 Affinity Capture-MS Homo sapiens 46 CBR3 874 Affinity Capture-MS Homo sapiens 47 PRKCA 5578 Affinity Capture-MS Homo sapiens 48 RRAS 6237 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 49 RNPS1 10921 Affinity Capture-MS Homo sapiens 50 PRKACB 5567 Affinity Capture-MS Homo sapiens 51 FYN 2534 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 52 CSTF3 1479 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 53 KRTAP12-2   Two-hybrid Homo sapiens 54 MND1   Affinity Capture-MS Homo sapiens 55 CLOCK   Affinity Capture-MS Homo sapiens 56 CSNK2A2 1459 Affinity Capture-MS Homo sapiens 57 CNTN1 1272 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 58 AP1B1 162 Affinity Capture-MS Homo sapiens 59 YES1 7525 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 60 ZBTB7B   Two-hybrid Homo sapiens 61 NF2 4771 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 62 PIGF   Affinity Capture-MS Homo sapiens 63 RUNDC3A   Two-hybrid Homo sapiens Two-hybrid Homo sapiens 64 PROCR 10544 Affinity Capture-MS Homo sapiens 65 KIFAP3 22920 Affinity Capture-MS Homo sapiens 66 C12orf75   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 67 SRC 6714 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 68 DIAPH1 1729 Affinity Capture-MS Homo sapiens 69 HSPA9 3313 Affinity Capture-MS Homo sapiens 70 IRF2BP2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 71 FBXO38 81545 Proximity Label-MS Homo sapiens 72 CAB39L 81617 Affinity Capture-MS Homo sapiens 73 BRD3 8019 Affinity Capture-MS Homo sapiens 74 SNX1 6642 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 75 LRRTM4   Affinity Capture-MS Homo sapiens 76 CDK11A 728642 Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 77 USP20   Two-hybrid Homo sapiens 78 CENPQ   Affinity Capture-MS Homo sapiens 79 CCNL1   Negative Genetic Homo sapiens 80 DYRK1A 1859 Biochemical Activity Homo sapiens View the network

Pathways in which CCNL2 is involved

No pathways found