Gene description for SUPT16H
Gene name suppressor of Ty 16 homolog (S. cerevisiae)
Gene symbol SUPT16H
Other names/aliases CDC68
FACTP140
SPT16
SPT16/CDC68
Species Homo sapiens
 Database cross references - SUPT16H
ExoCarta ExoCarta_11198
Vesiclepedia VP_11198
Entrez Gene 11198
HGNC 11465
MIM 605012
UniProt Q9Y5B9  
 SUPT16H identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Endothelial cells 26027894    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
T lymphocytes 34108659    
Thymus 23844026    
 Gene ontology annotations for SUPT16H
Molecular Function
    RNA binding GO:0003723 HDA
    protein binding GO:0005515 IPI
    nucleosome binding GO:0031491 IBA
Biological Process
    DNA replication GO:0006260 IEA
    DNA repair GO:0006281 IEA
    nucleosome assembly GO:0006334 NAS
    nucleosome disassembly GO:0006337 IDA
    transcription by RNA polymerase II GO:0006366 TAS
    transcription elongation by RNA polymerase II GO:0006368 IBA
    positive regulation of DNA-templated transcription, elongation GO:0032786 TAS
Subcellular Localization
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IDA
    nucleoplasm GO:0005654 TAS
    FACT complex GO:0035101 IBA
    FACT complex GO:0035101 IPI
 Experiment description of studies that identified SUPT16H in sEVs
1
Experiment ID 489
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
10
Experiment ID 498
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
11
Experiment ID 1203
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
12
Experiment ID 407
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
13
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
15
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
17
Experiment ID 226
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description "Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting"
Authors "Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar"
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
18
Experiment ID 405
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
19
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
20
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
21
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
22
Experiment ID 417
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
23
Experiment ID 411
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 488
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
25
Experiment ID 418
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 418
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 413
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 211
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
29
Experiment ID 212
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
30
Experiment ID 406
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 415
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
33
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
34
Experiment ID 408
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
35
Experiment ID 409
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
36
Experiment ID 416
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
37
Experiment ID 410
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
38
Experiment ID 217
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SUPT16H
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 IWS1  
Co-fractionation Homo sapiens
2 CD3EAP  
Proximity Label-MS Homo sapiens
3 HIST1H3I 8354
Affinity Capture-MS Homo sapiens
4 HIST2H2BE 8349
Affinity Capture-MS Homo sapiens
5 XPC  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 H2AFJ 55766
Affinity Capture-MS Homo sapiens
7 HIST1H4K 8362
Affinity Capture-MS Homo sapiens
8 PRKAA1 5562
Affinity Capture-MS Homo sapiens
9 ISG15 9636
Affinity Capture-MS Homo sapiens
10 NEB 4703
Cross-Linking-MS (XL-MS) Homo sapiens
11 FMNL1 752
Affinity Capture-MS Homo sapiens
12 MAFF 23764
Affinity Capture-MS Homo sapiens
13 COMMD6 170622
Affinity Capture-MS Homo sapiens
14 MACROD1 28992
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 COIL  
Proximity Label-MS Homo sapiens
16 MSH6 2956
Co-fractionation Homo sapiens
17 ANLN 54443
Affinity Capture-MS Homo sapiens
18 MKL1 57591
Affinity Capture-Western Homo sapiens
19 TOMM20 9804
Affinity Capture-MS Homo sapiens
20 SRPK2 6733
Biochemical Activity Homo sapiens
21 RIT1 6016
Negative Genetic Homo sapiens
22 NAA40  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 SSB 6741
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
24 RPA2 6118
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 ETAA1  
Affinity Capture-MS Homo sapiens
26 HIST1H2BG 8339
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 HIST1H3G 8355
Affinity Capture-MS Homo sapiens
28 BRCA1 672
Synthetic Growth Defect Homo sapiens
Co-localization Homo sapiens
29 CDK12 51755
Co-fractionation Homo sapiens
30 VDAC1 7416
Affinity Capture-MS Homo sapiens
31 RPL10 6134
Affinity Capture-MS Homo sapiens
32 TRIM33 51592
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
33 HIST1H2BB 3018
Affinity Capture-Western Homo sapiens
34 OTUD5 55593
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
35 CSNK2A1 1457
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
36 PRPF3  
Co-fractionation Homo sapiens
37 CAND1 55832
Affinity Capture-MS Homo sapiens
38 HNRNPR 10236
Co-fractionation Homo sapiens
39 SOX2  
Affinity Capture-MS Homo sapiens
40 CENPA  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
41 DNAJB6 10049
Proximity Label-MS Homo sapiens
42 HIST1H2BJ 8970
Affinity Capture-MS Homo sapiens
43 GOLGA7 51125
Affinity Capture-MS Homo sapiens
44 TCEB3 6924
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
45 PSIP1 11168
Co-fractionation Homo sapiens
46 HIST1H2BE 8344
Affinity Capture-MS Homo sapiens
47 MKRN1 23608
Affinity Capture-MS Homo sapiens
48 CHD4 1108
Affinity Capture-MS Homo sapiens
49 E2F4  
Affinity Capture-MS Homo sapiens
50 HIST1H2AB 8335
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
51 WDR76  
Affinity Capture-MS Homo sapiens
52 B3GNT2 10678
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
53 KIF23 9493
Affinity Capture-MS Homo sapiens
54 MCM2 4171
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
55 POLL  
Affinity Capture-MS Homo sapiens
56 SPIN1  
Affinity Capture-MS Homo sapiens
57 USP39 10713
Co-fractionation Homo sapiens
58 FBXW7  
Affinity Capture-MS Homo sapiens
59 PRC1 9055
Affinity Capture-MS Homo sapiens
60 BRCC3 79184
Affinity Capture-MS Homo sapiens
61 NPM1 4869
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
62 SNRPC 6631
Affinity Capture-MS Homo sapiens
63 FBL 2091
Proximity Label-MS Homo sapiens
64 H2AFY2 55506
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
65 OBSL1 23363
Affinity Capture-MS Homo sapiens
66 CUL4A 8451
Affinity Capture-Western Homo sapiens
67 ABCE1 6059
Affinity Capture-MS Homo sapiens
68 RTN1 6252
Affinity Capture-MS Homo sapiens
69 ARID1A 8289
Co-fractionation Homo sapiens
70 FANCD2  
Affinity Capture-MS Homo sapiens
71 HMGA2 8091
Affinity Capture-MS Homo sapiens
72 CENPQ  
Affinity Capture-MS Homo sapiens
73 EED  
Affinity Capture-MS Homo sapiens
74 ATG16L1 55054
Affinity Capture-MS Homo sapiens
75 SFN 2810
Affinity Capture-MS Homo sapiens
76 KLHL20  
Affinity Capture-MS Homo sapiens
77 Eif3i 54709
Affinity Capture-MS Mus musculus
78 MECP2 4204
Affinity Capture-MS Homo sapiens
79 Eif3a 13669
Affinity Capture-MS Mus musculus
80 ILF3 3609
Affinity Capture-MS Homo sapiens
81 CSNK2B 1460
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
82 HIST1H3H 8357
Affinity Capture-MS Homo sapiens
83 SREK1 140890
Affinity Capture-MS Homo sapiens
84 EEF1A1 1915
Co-fractionation Homo sapiens
85 KIF14 9928
Affinity Capture-MS Homo sapiens
86 APOBEC3C 27350
Affinity Capture-MS Homo sapiens
87 HSPA8 3312
Co-fractionation Homo sapiens
88 HIST1H4I 8294
Affinity Capture-MS Homo sapiens
89 WRN 7486
Affinity Capture-MS Homo sapiens
90 POLR1A 25885
Affinity Capture-MS Homo sapiens
91 CHMP4C 92421
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
92 H2AFZ 3015
Affinity Capture-MS Homo sapiens
93 NF2 4771
Affinity Capture-MS Homo sapiens
94 PRPF6 24148
Co-fractionation Homo sapiens
95 SRP9 6726
Affinity Capture-MS Homo sapiens
96 DLD 1738
Affinity Capture-MS Homo sapiens
97 COMMD4 54939
Affinity Capture-MS Homo sapiens
98 FOXC1  
Affinity Capture-MS Homo sapiens
99 PRPF8 10594
Co-fractionation Homo sapiens
100 DDX21 9188
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
101 HIST1H3E 8353
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
102 SRRM1 10250
Co-fractionation Homo sapiens
103 TOP2B 7155
Co-fractionation Homo sapiens
104 CUL4B 8450
Affinity Capture-Western Homo sapiens
105 PARK2  
Affinity Capture-MS Homo sapiens
106 XPO1 7514
Affinity Capture-MS Homo sapiens
107 PNKP 11284
Affinity Capture-MS Homo sapiens
108 HIST1H3C 8352
Affinity Capture-MS Homo sapiens
109 PHF14 9678
Affinity Capture-MS Homo sapiens
110 ACACA 31
Negative Genetic Homo sapiens
111 ACIN1 22985
Co-fractionation Homo sapiens
112 HIST1H2AE 3012
Affinity Capture-MS Homo sapiens
113 TRIM24  
Affinity Capture-MS Homo sapiens
114 RNF146  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
115 RTF1 23168
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
116 SMARCA5 8467
Co-fractionation Homo sapiens
117 VRK1 7443
Affinity Capture-MS Homo sapiens
118 RPL5 6125
Affinity Capture-MS Homo sapiens
119 HIST1H2AM 8336
Affinity Capture-MS Homo sapiens
120 UBR5 51366
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
121 PABPC1 26986
Co-fractionation Homo sapiens
122 Srp72  
Affinity Capture-MS Mus musculus
123 SNRPD1 6632
Co-fractionation Homo sapiens
124 NELFE 7936
Affinity Capture-MS Homo sapiens
125 BTF3 689
Affinity Capture-MS Homo sapiens
126 VCP 7415
Affinity Capture-MS Homo sapiens
127 NTRK1 4914
Affinity Capture-MS Homo sapiens
128 RPL31 6160
Proximity Label-MS Homo sapiens
129 ACTL6A 86
Co-fractionation Homo sapiens
130 HIST2H2AA3 8337
Cross-Linking-MS (XL-MS) Homo sapiens
131 RAD18  
Affinity Capture-MS Homo sapiens
132 SUMO2 6613
Reconstituted Complex Homo sapiens
133 ETFB 2109
Cross-Linking-MS (XL-MS) Homo sapiens
134 HIST2H2AA4 723790
Affinity Capture-MS Homo sapiens
135 HIST2H2AC 8338
Affinity Capture-MS Homo sapiens
136 RPA4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
137 CHMP4B 128866
Affinity Capture-MS Homo sapiens
138 DHX40  
Proximity Label-MS Homo sapiens
139 PRKDC 5591
Affinity Capture-MS Homo sapiens
140 DHX9 1660
Affinity Capture-MS Homo sapiens
141 HECTD1 25831
Affinity Capture-MS Homo sapiens
142 CTR9 9646
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
143 POLB 5423
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
144 DDX23 9416
Proximity Label-MS Homo sapiens
145 NKTR  
Co-fractionation Homo sapiens
146 POLR2A 5430
Co-fractionation Homo sapiens
147 HMGB1 3146
Co-fractionation Homo sapiens
148 PPM1G 5496
Affinity Capture-MS Homo sapiens
149 DAXX  
Affinity Capture-MS Homo sapiens
150 ALX3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
151 HMGB2 3148
Co-fractionation Homo sapiens
152 SIX2  
Affinity Capture-MS Homo sapiens
153 KDF1  
Affinity Capture-MS Homo sapiens
154 RSL1D1 26156
Affinity Capture-MS Homo sapiens
155 CETN1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
156 FGFBP1 9982
Affinity Capture-MS Homo sapiens
157 PPM1B 5495
Affinity Capture-MS Homo sapiens
158 TONSL  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-localization Homo sapiens
159 FTH1 2495
Co-fractionation Homo sapiens
160 HNRNPL 3191
Affinity Capture-MS Homo sapiens
161 NOP56 10528
Proximity Label-MS Homo sapiens
162 ZBTB2 57621
Affinity Capture-MS Homo sapiens
163 HIST1H3F 8968
Affinity Capture-MS Homo sapiens
164 GLUL 2752
Affinity Capture-MS Homo sapiens
165 PRPF4B 8899
Co-fractionation Homo sapiens
166 HIST1H3A 8350
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
167 Myh9 17886
Affinity Capture-MS Mus musculus
168 LEO1 123169
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
169 SMARCAD1  
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
170 MSH2 4436
Co-fractionation Homo sapiens
171 KIF20A 10112
Affinity Capture-MS Homo sapiens
172 UBE2H 7328
Affinity Capture-MS Homo sapiens
173 RC3H2  
Affinity Capture-MS Homo sapiens
174 ECT2 1894
Affinity Capture-MS Homo sapiens
175 CCDC82  
Affinity Capture-MS Homo sapiens
176 TAL1  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
177 BRD2  
Affinity Capture-MS Homo sapiens
178 MEX3A  
Affinity Capture-RNA Homo sapiens
179 CALR 811
Co-fractionation Homo sapiens
180 SUPT5H 6829
Affinity Capture-MS Homo sapiens
181 PHIP 55023
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
182 CUL3 8452
Affinity Capture-MS Homo sapiens
183 RPS6 6194
Proximity Label-MS Homo sapiens
184 UHRF2  
Affinity Capture-MS Homo sapiens
185 HIST3H2BB 128312
Affinity Capture-MS Homo sapiens
186 SNRPA 6626
Affinity Capture-MS Homo sapiens
187 MCM4 4173
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
188 PPIA 5478
Cross-Linking-MS (XL-MS) Homo sapiens
189 DLX6  
Affinity Capture-MS Homo sapiens
190 TEAD2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
191 SBF1 6305
Affinity Capture-MS Homo sapiens
192 EMX2  
Affinity Capture-MS Homo sapiens
193 NXF1 10482
Affinity Capture-RNA Homo sapiens
194 SF3A1 10291
Co-fractionation Homo sapiens
195 HIST1H3B 8358
Affinity Capture-MS Homo sapiens
196 CDK2 1017
Affinity Capture-MS Homo sapiens
197 HIST1H4B 8366
Affinity Capture-MS Homo sapiens
198 SSTR1 6751
Affinity Capture-MS Homo sapiens
199 DKC1 1736
Affinity Capture-MS Homo sapiens
200 POLR1E  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
201 HMGB3 3149
Co-fractionation Homo sapiens
202 HIST1H2BA 255626
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
203 ZC3H18  
Co-fractionation Homo sapiens
204 NAP1L1 4673
Co-fractionation Homo sapiens
205 DNAJC9 23234
Proximity Label-MS Homo sapiens
206 EGFR 1956
Negative Genetic Homo sapiens
207 CSNK2A2 1459
Co-fractionation Homo sapiens
208 TOP1 7150
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
209 NHP2L1 4809
Co-fractionation Homo sapiens
210 BRD4 23476
Affinity Capture-MS Homo sapiens
211 HIST1H4F 8361
Affinity Capture-MS Homo sapiens
212 MMS22L  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
213 H3F3B 3021
Affinity Capture-MS Homo sapiens
214 DDB1 1642
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
215 DDRGK1 65992
Affinity Capture-MS Homo sapiens
216 RNF2  
Affinity Capture-MS Homo sapiens
217 BMI1  
Affinity Capture-MS Homo sapiens
218 FYTTD1  
Affinity Capture-Western Homo sapiens
219 Rpl35 66489
Affinity Capture-MS Mus musculus
220 H2AFB2  
Affinity Capture-MS Homo sapiens
221 RPL11 6135
Affinity Capture-MS Homo sapiens
222 COMMD2 51122
Affinity Capture-MS Homo sapiens
223 NANOG  
Affinity Capture-MS Homo sapiens
224 Eif3e 16341
Affinity Capture-MS Mus musculus
225 HMG20A  
Affinity Capture-MS Homo sapiens
226 NCSTN 23385
Co-fractionation Homo sapiens
227 APLF  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
228 BRD3 8019
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
229 HIST1H2BI 8346
Affinity Capture-MS Homo sapiens
230 SUPT16H 11198
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
231 PYHIN1  
Affinity Capture-MS Homo sapiens
232 GNL3 26354
Affinity Capture-MS Homo sapiens
233 XRCC5 7520
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
234 SNRPD2 6633
Co-fractionation Homo sapiens
235 SPIN2B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
236 COMMD1 150684
Affinity Capture-MS Homo sapiens
237 H2AFX 3014
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
238 HIST1H3J 8356
Affinity Capture-MS Homo sapiens
239 Cbx1  
Affinity Capture-MS Mus musculus
240 DHX15 1665
Co-fractionation Homo sapiens
241 SIRT6  
Affinity Capture-MS Homo sapiens
242 MEN1 4221
Affinity Capture-MS Homo sapiens
243 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
244 FBXW11  
Affinity Capture-MS Homo sapiens
245 ATRX 546
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
246 H2BFWT  
Affinity Capture-MS Homo sapiens
247 PARP1 142
Biochemical Activity Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
248 HMGN4  
Affinity Capture-MS Homo sapiens
249 LIG3 3980
Affinity Capture-MS Homo sapiens
250 HDGF 3068
Affinity Capture-MS Homo sapiens
251 H3F3A 3020
Affinity Capture-MS Homo sapiens
252 TP53 7157
Affinity Capture-MS Homo sapiens
253 CHCHD1  
Proximity Label-MS Homo sapiens
254 RBM25 58517
Co-fractionation Homo sapiens
255 PES1 23481
Co-fractionation Homo sapiens
256 CDKN2A 1029
Affinity Capture-MS Homo sapiens
257 AAMP 14
Affinity Capture-MS Homo sapiens
258 USP36  
Affinity Capture-MS Homo sapiens
259 SAP18 10284
Co-fractionation Homo sapiens
260 HNRNPA2B1 3181
Cross-Linking-MS (XL-MS) Homo sapiens
261 PDHA1 5160
Affinity Capture-MS Homo sapiens
262 Atrx  
Affinity Capture-MS Mus musculus
263 HNRNPM 4670
Co-fractionation Homo sapiens
264 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
265 CHD1L 9557
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
266 RNF20 56254
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
267 H2AFB3  
Affinity Capture-MS Homo sapiens
268 S100A9 6280
Co-fractionation Homo sapiens
269 KRI1  
Co-fractionation Homo sapiens
270 ESR1  
Affinity Capture-MS Homo sapiens
271 UFL1 23376
Affinity Capture-MS Homo sapiens
272 IK 3550
Co-fractionation Homo sapiens
273 HIST1H4L 8368
Affinity Capture-MS Homo sapiens
274 MOV10 4343
Affinity Capture-RNA Homo sapiens
275 Rprd1b  
Affinity Capture-MS Mus musculus
276 QRICH1  
Co-fractionation Homo sapiens
277 TECTB  
Affinity Capture-MS Homo sapiens
278 CDK9 1025
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
279 PINK1  
Affinity Capture-MS Homo sapiens
280 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
281 L3MBTL1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
282 XRCC6 2547
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
283 HOXC12  
Affinity Capture-MS Homo sapiens
284 CUL7 9820
Affinity Capture-MS Homo sapiens
285 KRAS 3845
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
286 HNRNPU 3192
Affinity Capture-MS Homo sapiens
287 PAF1 54623
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
288 SSRP1 6749
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Co-purification Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
289 HSPA5 3309
Co-fractionation Homo sapiens
290 RPA3 6119
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
291 TXNDC2  
Affinity Capture-MS Homo sapiens
292 CDK11A 728642
Co-fractionation Homo sapiens
293 RANBP2 5903
Affinity Capture-MS Homo sapiens
294 TIPIN  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
295 COX15 1355
Affinity Capture-MS Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here