Gene description for SSB
Gene name Sjogren syndrome antigen B (autoantigen La)
Gene symbol SSB
Other names/aliases LARP3
La
La/SSB
Species Homo sapiens
 Database cross references - SSB
ExoCarta ExoCarta_6741
Vesiclepedia VP_6741
Entrez Gene 6741
HGNC 11316
MIM 109090
UniProt P05455  
 SSB identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 36706192    
Embryonic kidney cells 36706192    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
T lymphocytes 34108659    
 Gene ontology annotations for SSB
Molecular Function
    tRNA binding GO:0000049 IMP
    RNA binding GO:0003723 HDA
    RNA binding GO:0003723 IMP
    mRNA binding GO:0003729 IBA
    protein binding GO:0005515 IPI
    poly(U) RNA binding GO:0008266 IMP
    poly(U) RNA binding GO:0008266 IPI
    sequence-specific mRNA binding GO:1990825 IMP
Biological Process
    tRNA 5'-leader removal GO:0001682 IGI
    tRNA modification GO:0006400 TAS
    tRNA export from nucleus GO:0006409 IMP
    tRNA processing GO:0008033 IBA
    tRNA processing GO:0008033 IMP
    histone mRNA metabolic process GO:0008334 TAS
    tRNA 3'-end processing GO:0042780 IGI
    positive regulation of translation GO:0045727 IBA
    nuclear histone mRNA catabolic process GO:0071045 IMP
    IRES-dependent viral translational initiation GO:0075522 IDA
    protein localization to cytoplasmic stress granule GO:1903608 IDA
Subcellular Localization
    chromosome, telomeric region GO:0000781 HDA
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    cytoplasm GO:0005737 IDA
    cytosol GO:0005829 IBA
    cytoplasmic stress granule GO:0010494 IBA
    ribonucleoprotein complex GO:1990904 IEA
 Experiment description of studies that identified SSB in sEVs
1
Experiment ID 489
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX|ACTB
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 497
MISEV standards
Biophysical techniques
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
10
Experiment ID 498
MISEV standards
EM
Biophysical techniques
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
11
Experiment ID 1203
MISEV standards
EM
Biophysical techniques
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
12
Experiment ID 407
MISEV standards
EM
Biophysical techniques
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
13
Experiment ID 419
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 419
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
15
Experiment ID 420
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 420
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
17
Experiment ID 1275
MISEV standards
Biophysical techniques
CD9|TSG101|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
18
Experiment ID 1280
MISEV standards
Biophysical techniques
TSG101|CD9|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T - Fraction 5
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density 1.151 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
19
Experiment ID 405
MISEV standards
EM
Biophysical techniques
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
20
Experiment ID 363
MISEV standards
Biophysical techniques
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
DCLK1
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
21
Experiment ID 364
MISEV standards
Biophysical techniques
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
DCLK1
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
22
Experiment ID 365
MISEV standards
Biophysical techniques
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
DCLK1
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
23
Experiment ID 417
MISEV standards
EM
Biophysical techniques
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX|ACTB
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 411
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 488
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
26
Experiment ID 418
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 413
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 211
MISEV standards
EM
Biophysical techniques
TSG101|Alix|EpCAM|TFRC
Enriched markers
cytochrome c|GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
29
Experiment ID 212
MISEV standards
CEM
Biophysical techniques
TSG101|Alix|EpCAM|TFRC
Enriched markers
Cytochrome C|GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
30
Experiment ID 406
MISEV standards
EM
Biophysical techniques
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 415
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 434
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
33
Experiment ID 435
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
34
Experiment ID 408
MISEV standards
EM
Biophysical techniques
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX|ACTB
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
35
Experiment ID 409
MISEV standards
EM
Biophysical techniques
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
36
Experiment ID 416
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
37
Experiment ID 834
MISEV standards
EM
Biophysical techniques
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
38
Experiment ID 835
MISEV standards
EM
Biophysical techniques
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
39
Experiment ID 410
MISEV standards
EM
Biophysical techniques
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
 Protein-protein interactions for SSB
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 EIF3A 8661
Affinity Capture-MS Homo sapiens
2 RPSAP58 388524
Affinity Capture-MS Homo sapiens
3 HDAC4  
Affinity Capture-MS Homo sapiens
4 WDR6 11180
Affinity Capture-MS Homo sapiens
5 NPLOC4 55666
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
6 TPM2 7169
Co-fractionation Homo sapiens
7 CAP1 10487
Co-fractionation Homo sapiens
8 ACTC1 70
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
9 HIST1H2BH 8345
Cross-Linking-MS (XL-MS) Homo sapiens
10 UBC 7316
Affinity Capture-MS Homo sapiens
11 CSNK2A1 1457
Biochemical Activity Homo sapiens
12 KPNA2 3838
Affinity Capture-MS Homo sapiens
13 SOX2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
14 KIF23 9493
Affinity Capture-MS Homo sapiens
15 CCS 9973
Co-fractionation Homo sapiens
16 NUP153 9972
Affinity Capture-MS Homo sapiens
17 FBL 2091
Affinity Capture-MS Homo sapiens
18 ABI1 10006
Co-fractionation Homo sapiens
19 Nhp2l1 20826
Affinity Capture-MS Mus musculus
20 SNRPD3 6634
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
21 DUS1L 64118
Affinity Capture-MS Homo sapiens
22 ARIH2 10425
Affinity Capture-MS Homo sapiens
23 RPS11 6205
Affinity Capture-MS Homo sapiens
24 SOD1 6647
Affinity Capture-MS Homo sapiens
25 EEF1A1 1915
Co-fractionation Homo sapiens
26 KIF14 9928
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
27 KLF16  
Affinity Capture-MS Homo sapiens
28 TCP1 6950
Co-fractionation Homo sapiens
29 RPP14  
Affinity Capture-MS Homo sapiens
30 ARHGEF39 84904
Affinity Capture-MS Homo sapiens
31 CAPZA1 829
Co-fractionation Homo sapiens
32 IFIT5 24138
Affinity Capture-MS Homo sapiens
33 RRP9 9136
Affinity Capture-MS Homo sapiens
34 TRMT61A 115708
Affinity Capture-MS Homo sapiens
35 LDHC 3948
Affinity Capture-MS Homo sapiens
36 LRRFIP1 9208
Cross-Linking-MS (XL-MS) Homo sapiens
37 YWHAE 7531
Co-fractionation Homo sapiens
38 MYH9 4627
Co-fractionation Homo sapiens
39 OGT 8473
Reconstituted Complex Homo sapiens
40 RPL31 6160
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
41 NOB1  
Affinity Capture-MS Homo sapiens
42 HECTD1 25831
Affinity Capture-MS Homo sapiens
43 CUL2 8453
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
44 TRMT2A 27037
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
45 SEC61B 10952
Affinity Capture-MS Homo sapiens
46 METTL1 4234
Affinity Capture-MS Homo sapiens
47 SSR4 6748
Affinity Capture-MS Homo sapiens
48 HIST1H2BL 8340
Cross-Linking-MS (XL-MS) Homo sapiens
49 HSPA5 3309
Co-fractionation Homo sapiens
50 DOCK8 81704
Affinity Capture-MS Homo sapiens
51 TIPRL 261726
Co-fractionation Homo sapiens
52 LMNB1 4001
Co-fractionation Homo sapiens
53 HSPE1 3336
Cross-Linking-MS (XL-MS) Homo sapiens
54 SIRT7  
Affinity Capture-MS Homo sapiens
55 PRKAR1A 5573
Co-fractionation Homo sapiens
56 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
57 EPRS 2058
Co-fractionation Homo sapiens
58 FN1 2335
Affinity Capture-MS Homo sapiens
59 ARMC6 93436
Affinity Capture-MS Homo sapiens
60 UBA2 10054
Co-fractionation Homo sapiens
61 RPA3 6119
Proximity Label-MS Homo sapiens
62 RPP40 10799
Affinity Capture-MS Homo sapiens
63 DDX54 79039
Co-fractionation Homo sapiens
64 KIAA1109 84162
Cross-Linking-MS (XL-MS) Homo sapiens
65 HIST1H1A 3024
Affinity Capture-MS Homo sapiens
66 H19 283120
Protein-RNA Homo sapiens
67 AKT1 207
Co-fractionation Homo sapiens
68 RPS15A 6210
Affinity Capture-MS Homo sapiens
69 SUPT16H 11198
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
70 RPS16 6217
Affinity Capture-MS Homo sapiens
71 TLX1  
Affinity Capture-MS Homo sapiens
72 YBX1 4904
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
73 RPS27A 6233
Affinity Capture-MS Homo sapiens
74 FASN 2194
Co-fractionation Homo sapiens
75 COPZ1 22818
Co-fractionation Homo sapiens
76 ZNF593  
Co-fractionation Homo sapiens
77 MACF1 23499
Co-fractionation Homo sapiens
78 ZEB1  
Affinity Capture-MS Homo sapiens
79 CDC37 11140
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
80 HIST1H2BC 8347
Cross-Linking-MS (XL-MS) Homo sapiens
81 TRUB1 142940
Affinity Capture-MS Homo sapiens
82 CWF19L2  
Affinity Capture-MS Homo sapiens
83 PUF60 22827
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
84 TUT1  
Affinity Capture-MS Homo sapiens
85 KLF12  
Affinity Capture-MS Homo sapiens
86 PLEKHG4  
Affinity Capture-MS Homo sapiens
87 LARP7 51574
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
88 NEIL1  
Affinity Capture-MS Homo sapiens
89 RPS24 6229
Affinity Capture-MS Homo sapiens
90 NCL 4691
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
91 ARHGAP36  
Affinity Capture-MS Homo sapiens
92 EIF4B 1975
Cross-Linking-MS (XL-MS) Homo sapiens
Co-fractionation Homo sapiens
93 RDX 5962
Co-fractionation Homo sapiens
94 RPL23A 6147
Affinity Capture-MS Homo sapiens
95 NFIC 4782
Co-fractionation Homo sapiens
96 SNRPA1 6627
Co-fractionation Homo sapiens
97 FAN1  
Affinity Capture-MS Homo sapiens
98 ACOT7 11332
Affinity Capture-MS Homo sapiens
99 SMC3 9126
Co-fractionation Homo sapiens
100 ANP32A 8125
Co-fractionation Homo sapiens
101 EIF3K 27335
Affinity Capture-MS Homo sapiens
102 TARDBP 23435
Affinity Capture-MS Homo sapiens
103 NOP56 10528
Co-fractionation Homo sapiens
104 TRIM33 51592
Affinity Capture-MS Homo sapiens
105 ZFR 51663
Affinity Capture-MS Homo sapiens
106 RPL14 9045
Affinity Capture-MS Homo sapiens
107 CAND1 55832
Affinity Capture-MS Homo sapiens
108 SNRPF 6636
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
109 RPS3 6188
Co-fractionation Homo sapiens
110 RPS18 6222
Affinity Capture-MS Homo sapiens
111 SURF2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
112 TLN1 7094
Co-fractionation Homo sapiens
113 NPM1 4869
Co-fractionation Homo sapiens
114 KLF15  
Affinity Capture-MS Homo sapiens
115 TOM1 10043
Co-fractionation Homo sapiens
116 RSRC1  
Affinity Capture-MS Homo sapiens
117 Clp1  
Affinity Capture-MS Mus musculus
118 KLF4  
Affinity Capture-MS Homo sapiens
119 DDX6 1656
Affinity Capture-MS Homo sapiens
120 CUL1 8454
Affinity Capture-MS Homo sapiens
121 PLCB3 5331
Co-fractionation Homo sapiens
122 DHX36 170506
Affinity Capture-MS Homo sapiens
123 PRNP 5621
Affinity Capture-MS Homo sapiens
124 ZCRB1  
Affinity Capture-MS Homo sapiens
125 YWHAB 7529
Co-fractionation Homo sapiens
126 CCT2 10576
Co-fractionation Homo sapiens
127 DSG1 1828
Affinity Capture-MS Homo sapiens
128 HIST1H4A 8359
Co-fractionation Homo sapiens
129 DDX21 9188
Affinity Capture-MS Homo sapiens
130 RPL4 6124
Affinity Capture-MS Homo sapiens
131 TRIM24  
Affinity Capture-MS Homo sapiens
132 VRK1 7443
Affinity Capture-MS Homo sapiens
133 RPL35 11224
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
134 SNRPD1 6632
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
135 PPP2CA 5515
Co-fractionation Homo sapiens
136 GAPDH 2597
Co-fractionation Homo sapiens
137 BCL6  
Affinity Capture-MS Homo sapiens
138 RPLP0 6175
Affinity Capture-MS Homo sapiens
139 DDX27 55661
Co-fractionation Homo sapiens
140 CYLD  
Affinity Capture-MS Homo sapiens
141 SNRPB2 6629
Co-fractionation Homo sapiens
142 RSL1D1 26156
Affinity Capture-MS Homo sapiens
143 PLEKHG6  
Affinity Capture-MS Homo sapiens
144 VCY  
Cross-Linking-MS (XL-MS) Homo sapiens
145 HNRNPD 3184
Affinity Capture-MS Homo sapiens
146 PER2  
Proximity Label-MS Homo sapiens
147 RPS2 6187
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
148 POP1 10940
Affinity Capture-MS Homo sapiens
149 CALR 811
Co-fractionation Homo sapiens
150 RPS7 6201
Affinity Capture-MS Homo sapiens
151 SRSF5 6430
Affinity Capture-MS Homo sapiens
152 EGFR 1956
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
153 HSD17B10 3028
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
154 TFG 10342
Co-fractionation Homo sapiens
155 CDK2 1017
Affinity Capture-MS Homo sapiens
156 TADA2A  
Affinity Capture-MS Homo sapiens
157 MYC  
Affinity Capture-MS Homo sapiens
158 BAG1 573
Affinity Capture-MS Homo sapiens
159 HNRNPAB 3182
Affinity Capture-MS Homo sapiens
160 DDRGK1 65992
Affinity Capture-MS Homo sapiens
161 BMI1  
Affinity Capture-MS Homo sapiens
162 ARGLU1  
Affinity Capture-MS Homo sapiens
163 HUWE1 10075
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
164 EIF3H 8667
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
165 RPL19 6143
Affinity Capture-MS Homo sapiens
166 RPL13 6137
Affinity Capture-MS Homo sapiens
167 TSEN34 79042
Affinity Capture-MS Homo sapiens
168 DIDO1  
Cross-Linking-MS (XL-MS) Homo sapiens
169 ILF3 3609
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
170 RPP25L  
Affinity Capture-MS Homo sapiens
171 SPP1 6696
Two-hybrid Homo sapiens
172 RPS4X 6191
Affinity Capture-MS Homo sapiens
173 OTUB1 55611
Co-fractionation Homo sapiens
174 RPS5 6193
Affinity Capture-MS Homo sapiens
175 NIFK 84365
Co-fractionation Homo sapiens
176 HNRNPK 3190
Co-fractionation Homo sapiens
177 RPS26 6231
Affinity Capture-MS Homo sapiens
178 RPL7A 6130
Affinity Capture-MS Homo sapiens
179 RPL27 6155
Affinity Capture-MS Homo sapiens
180 KRAS 3845
Negative Genetic Homo sapiens
181 NEFM 4741
Cross-Linking-MS (XL-MS) Homo sapiens
182 ATOH1  
Affinity Capture-MS Homo sapiens
183 PRMT1 3276
Affinity Capture-MS Homo sapiens
184 RPP38 10557
Affinity Capture-MS Homo sapiens
185 SULT2B1 6820
Co-fractionation Homo sapiens
186 LSM2 57819
Co-fractionation Homo sapiens
187 UBE2H 7328
Affinity Capture-MS Homo sapiens
188 NOP58 51602
Affinity Capture-MS Homo sapiens
189 SNRPE 6635
Affinity Capture-MS Homo sapiens
190 SP1  
Co-fractionation Homo sapiens
191 TGS1  
Affinity Capture-MS Homo sapiens
192 RPS19 6223
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
193 BYSL 705
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
194 EFTUD1 79631
Co-fractionation Homo sapiens
195 TRMT6 51605
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
196 HNRNPR 10236
Co-fractionation Homo sapiens
197 PTPN1 5770
Co-fractionation Homo sapiens
198 FAU 2197
Affinity Capture-MS Homo sapiens
199 CAPZB 832
Co-fractionation Homo sapiens
200 RPL10A 4736
Affinity Capture-MS Homo sapiens
201 SART3 9733
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
202 HEATR3 55027
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
203 ANKMY2 57037
Co-fractionation Homo sapiens
204 WDR74 54663
Co-fractionation Homo sapiens
205 NHP2 55651
Affinity Capture-MS Homo sapiens
206 GTF3A 2971
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
207 PABPC4 8761
Affinity Capture-MS Homo sapiens
208 LIN28A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
209 DUS2 54920
Affinity Capture-MS Homo sapiens
210 EIF2AK2 5610
Affinity Capture-MS Homo sapiens
211 NSUN2 54888
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
212 ATP5A1 498
Co-fractionation Homo sapiens
213 FOXC1  
Affinity Capture-MS Homo sapiens
214 CUL4B 8450
Affinity Capture-MS Homo sapiens
215 PARK2  
Affinity Capture-MS Homo sapiens
216 RPS10 6204
Affinity Capture-MS Homo sapiens
217 MARS 4141
Cross-Linking-MS (XL-MS) Homo sapiens
218 CBX3 11335
Proximity Label-MS Homo sapiens
219 RPL5 6125
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
220 SAFB2 9667
Co-fractionation Homo sapiens
221 BARD1 580
Affinity Capture-MS Homo sapiens
222 NTRK1 4914
Affinity Capture-MS Homo sapiens
223 PABPC1 26986
Co-fractionation Homo sapiens
224 HIST1H1E 3008
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
225 RPL36 25873
Affinity Capture-MS Homo sapiens
226 RPLP1 6176
Affinity Capture-MS Homo sapiens
227 DHX9 1660
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
228 Ybx1 22608
Affinity Capture-MS Mus musculus
229 HIST1H2BK 85236
Cross-Linking-MS (XL-MS) Homo sapiens
230 HNRNPA3 220988
Co-fractionation Homo sapiens
231 DNM1L 10059
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
232 EIF2B4 8890
Affinity Capture-MS Homo sapiens
233 RPL11 6135
Affinity Capture-MS Homo sapiens
234 LARP1 23367
Affinity Capture-MS Homo sapiens
235 CASP4  
Co-fractionation Homo sapiens
236 HNRNPDL 9987
Affinity Capture-MS Homo sapiens
237 SPIB  
Two-hybrid Homo sapiens
238 CCNA2 890
Affinity Capture-MS Homo sapiens
239 AHCY 191
Co-fractionation Homo sapiens
240 TRMT10C 54931
Affinity Capture-MS Homo sapiens
241 TXNDC5 81567
Co-fractionation Homo sapiens
242 U2AF2 11338
Affinity Capture-MS Homo sapiens
243 HSP90AB1 3326
Co-fractionation Homo sapiens
244 SF1 7536
Affinity Capture-MS Homo sapiens
245 METTL16 79066
Affinity Capture-MS Homo sapiens
246 RPL21 6144
Affinity Capture-MS Homo sapiens
247 CCT4 10575
Co-fractionation Homo sapiens
248 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
249 DHX30 22907
Affinity Capture-MS Homo sapiens
250 HNRNPUL1 11100
Affinity Capture-MS Homo sapiens
251 PUS7 54517
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
252 DUS3L 56931
Affinity Capture-MS Homo sapiens
253 PDCD4 27250
Affinity Capture-MS Homo sapiens
254 PRPF19 27339
Co-fractionation Homo sapiens
255 RPS13 6207
Affinity Capture-MS Homo sapiens
256 NHP2L1 4809
Affinity Capture-MS Homo sapiens
257 RPL22 6146
Affinity Capture-MS Homo sapiens
258 SKIV2L2 23517
Affinity Capture-MS Homo sapiens
259 PPP6C 5537
Affinity Capture-MS Homo sapiens
260 ACTB 60
Co-fractionation Homo sapiens
261 RPL18 6141
Cross-Linking-MS (XL-MS) Homo sapiens
262 RNF2  
Affinity Capture-MS Homo sapiens
263 ZC3HAV1 56829
Affinity Capture-MS Homo sapiens
264 MSN 4478
Co-fractionation Homo sapiens
265 TSR1 55720
Affinity Capture-MS Homo sapiens
266 HDGF 3068
Affinity Capture-MS Homo sapiens
267 POP7  
Affinity Capture-MS Homo sapiens
268 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
269 CCT8 10694
Co-fractionation Homo sapiens
270 RPS25 6230
Affinity Capture-MS Homo sapiens
271 ITSN1 6453
Affinity Capture-MS Homo sapiens
272 FBXL6  
Affinity Capture-MS Homo sapiens
273 THUMPD3 25917
Co-fractionation Homo sapiens
274 PRRC2C 23215
Co-fractionation Homo sapiens
275 POP4 10775
Affinity Capture-MS Homo sapiens
276 G3BP1 10146
Co-fractionation Homo sapiens
277 TSEN2  
Affinity Capture-MS Homo sapiens
278 CCT7 10574
Co-fractionation Homo sapiens
279 UFL1 23376
Affinity Capture-MS Homo sapiens
280 Casc5  
Affinity Capture-MS Mus musculus
281 GLUL 2752
Co-fractionation Homo sapiens
282 PMVK 10654
Affinity Capture-MS Homo sapiens
283 TRMT5  
Affinity Capture-MS Homo sapiens
284 CIT 11113
Affinity Capture-MS Homo sapiens
285 RPS27L 51065
Affinity Capture-MS Homo sapiens
286 SERBP1 26135
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
287 ARHGAP24  
Affinity Capture-MS Homo sapiens
288 RBM34  
Co-fractionation Homo sapiens
289 SSRP1 6749
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
290 TFAM 7019
Cross-Linking-MS (XL-MS) Homo sapiens
291 TIMM44 10469
Cross-Linking-MS (XL-MS) Homo sapiens
292 EP300 2033
Affinity Capture-MS Homo sapiens
293 EIF3L 51386
Co-fractionation Homo sapiens
294 RPSA 3921
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
295 IGF2BP1 10642
Affinity Capture-MS Homo sapiens
296 XIAP  
Affinity Capture-RNA Homo sapiens
297 PAXIP1  
Affinity Capture-MS Homo sapiens
298 RPS3A 6189
Affinity Capture-MS Homo sapiens
299 CPOX 1371
Co-fractionation Homo sapiens
300 PPIE 10450
Affinity Capture-MS Homo sapiens
301 TNRC18  
Cross-Linking-MS (XL-MS) Homo sapiens
302 RPL13A 23521
Affinity Capture-MS Homo sapiens
303 KPNB1 3837
Affinity Capture-MS Homo sapiens
304 SUB1 10923
Affinity Capture-MS Homo sapiens
305 PTP4A1 7803
Affinity Capture-MS Homo sapiens
306 KARS 3735
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
307 TROVE2 6738
Co-purification Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
308 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
Affinity Capture-MS Homo sapiens
309 CCDC124 115098
Affinity Capture-MS Homo sapiens
310 SNRPD2 6633
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
311 APP 351
Reconstituted Complex Homo sapiens
312 KIAA1429 25962
Affinity Capture-MS Homo sapiens
313 SRP54 6729
Affinity Capture-MS Homo sapiens
314 RPS20 6224
Affinity Capture-MS Homo sapiens
315 PRDX3 10935
Co-fractionation Homo sapiens
316 CCT6A 908
Co-fractionation Homo sapiens
317 COPS5 10987
Affinity Capture-MS Homo sapiens
318 IFIT3 3437
Affinity Capture-MS Homo sapiens
319 TRIT1  
Affinity Capture-MS Homo sapiens
320 SRP68 6730
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
321 KRR1 11103
Affinity Capture-MS Homo sapiens
322 MYCN  
Affinity Capture-MS Homo sapiens
323 NEDD8 4738
Affinity Capture-MS Homo sapiens
324 ERI1  
Affinity Capture-MS Homo sapiens
325 ESR1  
Affinity Capture-MS Homo sapiens
326 ADSL 158
Co-fractionation Homo sapiens
327 GARS 2617
Co-fractionation Homo sapiens
328 SRP9 6726
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
329 ARHGAP12  
Affinity Capture-MS Homo sapiens
330 Arhgap28  
Affinity Capture-MS Mus musculus
331 EMD 2010
Affinity Capture-MS Homo sapiens
332 RPL39 6170
Affinity Capture-MS Homo sapiens
333 STAU1 6780
Affinity Capture-MS Homo sapiens
334 CCT5 22948
Co-fractionation Homo sapiens
335 SRSF6 6431
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
336 DDX5 1655
Co-fractionation Homo sapiens
337 IFI16 3428
Affinity Capture-MS Homo sapiens
338 RPL27A 6157
Affinity Capture-MS Homo sapiens
339 BRAF  
Affinity Capture-MS Homo sapiens
340 POLE  
Co-fractionation Homo sapiens
341 PRPF31 26121
Affinity Capture-MS Homo sapiens
342 CEBPA  
Protein-peptide Homo sapiens
343 DNAJB11 51726
Co-fractionation Homo sapiens
344 U2AF1 7307
Affinity Capture-MS Homo sapiens
345 MAT2A 4144
Co-fractionation Homo sapiens
346 BCCIP 56647
Co-fractionation Homo sapiens
347 RABGGTA 5875
Co-fractionation Homo sapiens
348 RPLP2 6181
Affinity Capture-MS Homo sapiens
349 SNRPB 6628
Affinity Capture-MS Homo sapiens
350 NAT10 55226
Co-fractionation Homo sapiens
351 CTTN 2017
Co-fractionation Homo sapiens
352 RPL3 6122
Affinity Capture-MS Homo sapiens
353 RPP30 10556
Affinity Capture-MS Homo sapiens
354 Mical3  
Affinity Capture-MS Mus musculus
355 Mphosph9  
Affinity Capture-MS Mus musculus
356 Bsdc1  
Affinity Capture-MS Mus musculus
357 RPL7 6129
Affinity Capture-MS Homo sapiens
358 SUZ12  
Affinity Capture-MS Homo sapiens
359 PRKCI 5584
Affinity Capture-MS Homo sapiens
360 MRPL1  
Affinity Capture-MS Homo sapiens
361 IL7R  
Protein-RNA Homo sapiens
362 VDAC1 7416
Affinity Capture-MS Homo sapiens
363 C9orf72  
Affinity Capture-MS Homo sapiens
364 H2AFX 3014
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
365 EXOSC10 5394
Co-fractionation Homo sapiens
366 SNCA 6622
Affinity Capture-MS Homo sapiens
367 KIAA1549  
Cross-Linking-MS (XL-MS) Homo sapiens
368 VBP1 7411
Co-fractionation Homo sapiens
369 SIRT6  
Affinity Capture-MS Homo sapiens
370 ZRANB2 9406
Co-fractionation Homo sapiens
371 RAD17  
Cross-Linking-MS (XL-MS) Homo sapiens
372 SAP130  
Co-fractionation Homo sapiens
373 SOX15  
Affinity Capture-MS Homo sapiens
374 TBC1D9  
Affinity Capture-MS Homo sapiens
375 POLR1C 9533
Co-fractionation Homo sapiens
376 SMURF1 57154
Affinity Capture-MS Homo sapiens
377 RPS15 6209
Affinity Capture-MS Homo sapiens
378 SRP72 6731
Affinity Capture-MS Homo sapiens
379 HIST1H2BD 3017
Cross-Linking-MS (XL-MS) Homo sapiens
380 RPS28 6234
Affinity Capture-MS Homo sapiens
381 NUP50 10762
Proximity Label-MS Homo sapiens
382 PINK1  
Affinity Capture-MS Homo sapiens
383 RPS8 6202
Affinity Capture-MS Homo sapiens
384 GRSF1 2926
Proximity Label-MS Homo sapiens
385 XRCC6 2547
Proximity Label-MS Homo sapiens
386 EIF3M 10480
Affinity Capture-MS Homo sapiens
387 PAF1 54623
Affinity Capture-MS Homo sapiens
388 RPL17 6139
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here