Gene description for AUH
Gene name AU RNA binding protein/enoyl-CoA hydratase
Gene symbol AUH
Other names/aliases -
Species Homo sapiens
 Database cross references - AUH
ExoCarta ExoCarta_549
Vesiclepedia VP_549
Entrez Gene 549
HGNC 890
MIM 600529
UniProt Q13825  
 AUH identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for AUH
Molecular Function
    mRNA 3'-UTR binding GO:0003730 IDA
    enoyl-CoA hydratase activity GO:0004300 IBA
    enoyl-CoA hydratase activity GO:0004300 IDA
    methylglutaconyl-CoA hydratase activity GO:0004490 IDA
    itaconyl-CoA hydratase activity GO:0050011 IEA
Biological Process
    L-leucine catabolic process GO:0006552 IEA
    fatty acid beta-oxidation GO:0006635 IBA
Subcellular Localization
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IBA
    mitochondrion GO:0005739 ISS
    mitochondrial matrix GO:0005759 TAS
 Experiment description of studies that identified AUH in sEVs
1
Experiment ID 489
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for AUH
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 MRPL41 64975
Proximity Label-MS Homo sapiens
2 PDHA1 5160
Proximity Label-MS Homo sapiens
3 MRPS27 23107
Proximity Label-MS Homo sapiens
4 AFG3L2 10939
Proximity Label-MS Homo sapiens
5 SLIRP 81892
Proximity Label-MS Homo sapiens
6 UQCRFS1 7386
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
7 OXCT1 5019
Proximity Label-MS Homo sapiens
8 MRPL48  
Proximity Label-MS Homo sapiens
9 DNAJC11 55735
Co-fractionation Homo sapiens
10 SARS2 54938
Proximity Label-MS Homo sapiens
11 ATP5J2-PTCD1  
Proximity Label-MS Homo sapiens
12 NARS2  
Proximity Label-MS Homo sapiens
13 NDUFS1 4719
Proximity Label-MS Homo sapiens
14 MRPS30 10884
Proximity Label-MS Homo sapiens
15 TRMT61B  
Proximity Label-MS Homo sapiens
16 MRPL17  
Proximity Label-MS Homo sapiens
17 ANGEL2 90806
Proximity Label-MS Homo sapiens
18 OXLD1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 GTPBP10  
Proximity Label-MS Homo sapiens
20 NDUFA7 4701
Proximity Label-MS Homo sapiens
21 PDK3 5165
Proximity Label-MS Homo sapiens
22 SUCLG1 8802
Proximity Label-MS Homo sapiens
23 ALDH2 217
Proximity Label-MS Homo sapiens
24 MTG2  
Proximity Label-MS Homo sapiens
25 NGRN  
Proximity Label-MS Homo sapiens
26 MRPL24  
Proximity Label-MS Homo sapiens
27 CDK5RAP1  
Proximity Label-MS Homo sapiens
28 ETFB 2109
Proximity Label-MS Homo sapiens
29 NDUFS7 374291
Proximity Label-MS Homo sapiens
30 MRPL50 54534
Proximity Label-MS Homo sapiens
31 BPNT1 10380
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
32 GATB  
Proximity Label-MS Homo sapiens
33 MRRF  
Proximity Label-MS Homo sapiens
34 GRPEL1 80273
Proximity Label-MS Homo sapiens
35 MRPL49 740
Proximity Label-MS Homo sapiens
36 MRPL23 6150
Proximity Label-MS Homo sapiens
37 PDE12 201626
Proximity Label-MS Homo sapiens
38 NDUFS2 4720
Proximity Label-MS Homo sapiens
39 SUPV3L1 6832
Proximity Label-MS Homo sapiens
40 ATP5L 10632
Proximity Label-MS Homo sapiens
41 CARS2 79587
Proximity Label-MS Homo sapiens
42 LRPPRC 10128
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
43 NOA1  
Proximity Label-MS Homo sapiens
44 TRUB2  
Proximity Label-MS Homo sapiens
45 ATP5D 513
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
46 MRPL20 55052
Proximity Label-MS Homo sapiens
47 NDUFS3 4722
Proximity Label-MS Homo sapiens
48 OGDH 4967
Proximity Label-MS Homo sapiens
49 PRDX3 10935
Proximity Label-MS Homo sapiens
50 PDK1 5163
Proximity Label-MS Homo sapiens
51 IARS2 55699
Proximity Label-MS Homo sapiens
52 DDX24 57062
Proximity Label-MS Homo sapiens
53 SDHB 6390
Proximity Label-MS Homo sapiens
54 EARS2  
Proximity Label-MS Homo sapiens
55 RAD21 5885
Proximity Label-MS Homo sapiens
56 HARS2 23438
Proximity Label-MS Homo sapiens
57 MRPS5 64969
Proximity Label-MS Homo sapiens
58 YARS2  
Proximity Label-MS Homo sapiens
59 HINT2 84681
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
60 MRPS23 51649
Proximity Label-MS Homo sapiens
61 MRPS24 64951
Proximity Label-MS Homo sapiens
62 MRPL12 6182
Proximity Label-MS Homo sapiens
63 ETFA 2108
Proximity Label-MS Homo sapiens
64 IBA57  
Proximity Label-MS Homo sapiens
65 AASS  
Proximity Label-MS Homo sapiens
66 ACOT2 10965
Proximity Label-MS Homo sapiens
67 ATP5O 539
Proximity Label-MS Homo sapiens
68 NNT 23530
Proximity Label-MS Homo sapiens
69 C20orf24  
Co-fractionation Homo sapiens
70 ERAL1  
Proximity Label-MS Homo sapiens
71 THEM4  
Proximity Label-MS Homo sapiens
72 MRPL39 54148
Proximity Label-MS Homo sapiens
73 NDUFAF1  
Proximity Label-MS Homo sapiens
74 NDUFAB1 4706
Proximity Label-MS Homo sapiens
75 ATP5H 10476
Proximity Label-MS Homo sapiens
76 SLC30A9 10463
Proximity Label-MS Homo sapiens
77 BCS1L 617
Proximity Label-MS Homo sapiens
78 SUCLA2 8803
Proximity Label-MS Homo sapiens
79 MRPL4 51073
Proximity Label-MS Homo sapiens
80 FASTKD2  
Proximity Label-MS Homo sapiens
81 NME4 4833
Proximity Label-MS Homo sapiens
82 NDUFA6  
Proximity Label-MS Homo sapiens
83 MTIF2 4528
Proximity Label-MS Homo sapiens
84 MRPL47 57129
Proximity Label-MS Homo sapiens
85 MRPS17 51373
Proximity Label-MS Homo sapiens
86 MTERF3  
Proximity Label-MS Homo sapiens
87 NFU1 27247
Proximity Label-MS Homo sapiens
88 MDH2 4191
Proximity Label-MS Homo sapiens
89 PAM16  
Proximity Label-MS Homo sapiens
90 STOML2 30968
Proximity Label-MS Homo sapiens
91 GARS 2617
Proximity Label-MS Homo sapiens
92 ALAS1  
Proximity Label-MS Homo sapiens
93 MRPS25 64432
Proximity Label-MS Homo sapiens
94 MRPL32 64983
Proximity Label-MS Homo sapiens
95 MRPS33  
Proximity Label-MS Homo sapiens
96 P4HA1 5033
Co-fractionation Homo sapiens
97 NDUFS4 4724
Proximity Label-MS Homo sapiens
98 NDUFAF3 25915
Proximity Label-MS Homo sapiens
99 FASTKD5  
Proximity Label-MS Homo sapiens
100 MRPL45 84311
Proximity Label-MS Homo sapiens
101 MRPS26 64949
Proximity Label-MS Homo sapiens
102 MRPS34 65993
Proximity Label-MS Homo sapiens
103 CENPV 201161
Proximity Label-MS Homo sapiens
104 HSP90B1 7184
Co-fractionation Homo sapiens
105 POLRMT 5442
Proximity Label-MS Homo sapiens
106 NT5DC2 64943
Proximity Label-MS Homo sapiens
107 ATPAF1  
Proximity Label-MS Homo sapiens
108 NTPCR 84284
Proximity Label-MS Homo sapiens
109 PTCD3 55037
Proximity Label-MS Homo sapiens
110 NDUFAF5  
Proximity Label-MS Homo sapiens
111 NDUFS8 4728
Proximity Label-MS Homo sapiens
112 MMAB 326625
Proximity Label-MS Homo sapiens
113 MRPL51 51258
Proximity Label-MS Homo sapiens
114 MRPS6  
Proximity Label-MS Homo sapiens
115 LYRM7  
Proximity Label-MS Homo sapiens
116 HNRNPAB 3182
Proximity Label-MS Homo sapiens
117 TARS2 80222
Proximity Label-MS Homo sapiens
118 POLDIP2 26073
Proximity Label-MS Homo sapiens
119 NDUFA2 4695
Proximity Label-MS Homo sapiens
120 KIAA0391  
Proximity Label-MS Homo sapiens
121 DDX54 79039
Proximity Label-MS Homo sapiens
122 FOSB  
Affinity Capture-MS Homo sapiens
123 RNMTL1  
Proximity Label-MS Homo sapiens
124 LACTB 114294
Co-fractionation Homo sapiens
125 DBT 1629
Proximity Label-MS Homo sapiens
126 HNRNPL 3191
Proximity Label-MS Homo sapiens
127 MRPL22  
Proximity Label-MS Homo sapiens
128 NDUFV3 4731
Proximity Label-MS Homo sapiens
129 MRPL14 64928
Proximity Label-MS Homo sapiens
130 COX7B 1349
Co-fractionation Homo sapiens
131 ATP5B 506
Proximity Label-MS Homo sapiens
132 ACN9  
Proximity Label-MS Homo sapiens
133 MRPL2 51069
Proximity Label-MS Homo sapiens
134 ABCB7 22
Proximity Label-MS Homo sapiens
135 COX4I1 1327
Proximity Label-MS Homo sapiens
136 GTPBP3  
Proximity Label-MS Homo sapiens
137 NDUFV1 4723
Proximity Label-MS Homo sapiens
138 OXA1L  
Proximity Label-MS Homo sapiens
139 HNRNPDL 9987
Proximity Label-MS Homo sapiens
140 ECH1 1891
Proximity Label-MS Homo sapiens
141 MRPL44  
Proximity Label-MS Homo sapiens
142 TRMT5  
Proximity Label-MS Homo sapiens
143 ACAT1 38
Proximity Label-MS Homo sapiens
144 MRPL40 64976
Proximity Label-MS Homo sapiens
145 COX5B 1329
Affinity Capture-MS Homo sapiens
146 OAT 4942
Proximity Label-MS Homo sapiens
147 NUBPL 80224
Proximity Label-MS Homo sapiens
148 MRPL21 219927
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
149 HADHA 3030
Proximity Label-MS Homo sapiens
150 THG1L 54974
Proximity Label-MS Homo sapiens
151 MRPL10 124995
Proximity Label-MS Homo sapiens
152 DAP3 7818
Proximity Label-MS Homo sapiens
153 TRMT10C 54931
Proximity Label-MS Homo sapiens
154 PNPT1 87178
Proximity Label-MS Homo sapiens
155 MRPS35 60488
Proximity Label-MS Homo sapiens
156 NDUFA9 4704
Proximity Label-MS Homo sapiens
157 MGME1  
Proximity Label-MS Homo sapiens
158 HSPE1 3336
Proximity Label-MS Homo sapiens
159 MRPS11  
Proximity Label-MS Homo sapiens
160 LETM1 3954
Proximity Label-MS Homo sapiens
161 RTN4IP1  
Proximity Label-MS Homo sapiens
162 CTNNB1 1499
Co-fractionation Homo sapiens
163 GCDH 2639
Proximity Label-MS Homo sapiens
164 MRPL27 51264
Proximity Label-MS Homo sapiens
165 MRPL9 65005
Proximity Label-MS Homo sapiens
166 MRPS14  
Proximity Label-MS Homo sapiens
167 MRPL16  
Proximity Label-MS Homo sapiens
168 NFS1 9054
Proximity Label-MS Homo sapiens
169 WBSCR16  
Proximity Label-MS Homo sapiens
170 ATP5F1 515
Proximity Label-MS Homo sapiens
171 MRPL42  
Proximity Label-MS Homo sapiens
172 ECHDC2 55268
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
173 PYCR1 5831
Proximity Label-MS Homo sapiens
174 HSD17B10 3028
Proximity Label-MS Homo sapiens
175 ELAC2 60528
Proximity Label-MS Homo sapiens
176 GADD45GIP1  
Proximity Label-MS Homo sapiens
177 DHX30 22907
Proximity Label-MS Homo sapiens
178 VARS2  
Proximity Label-MS Homo sapiens
179 PYCR2 29920
Proximity Label-MS Homo sapiens
180 PDCD11 22984
Proximity Label-MS Homo sapiens
181 ECHS1 1892
Proximity Label-MS Homo sapiens
182 DHTKD1 55526
Proximity Label-MS Homo sapiens
183 GLUD1 2746
Proximity Label-MS Homo sapiens
184 MRPL15 29088
Proximity Label-MS Homo sapiens
185 TM9SF3 56889
Proximity Label-MS Homo sapiens
186 ECI2 10455
Proximity Label-MS Homo sapiens
187 MRPL1  
Proximity Label-MS Homo sapiens
188 BIRC6 57448
Affinity Capture-MS Homo sapiens
189 MUT 4594
Proximity Label-MS Homo sapiens
190 MRPL19 9801
Proximity Label-MS Homo sapiens
191 COX6C 1345
Co-fractionation Homo sapiens
192 TACO1  
Proximity Label-MS Homo sapiens
193 MRPL37 51253
Proximity Label-MS Homo sapiens
194 DLST 1743
Proximity Label-MS Homo sapiens
195 PREPL 9581
Proximity Label-MS Homo sapiens
196 HSDL2 84263
Proximity Label-MS Homo sapiens
197 ACAD9 28976
Proximity Label-MS Homo sapiens
198 MRPL3  
Proximity Label-MS Homo sapiens
199 CLPX 10845
Proximity Label-MS Homo sapiens
200 FOXRED1  
Proximity Label-MS Homo sapiens
201 MRPS36 92259
Proximity Label-MS Homo sapiens
202 MTHFD2 10797
Proximity Label-MS Homo sapiens
203 PDPR 55066
Proximity Label-MS Homo sapiens
204 RBFA  
Proximity Label-MS Homo sapiens
205 HSPD1 3329
Proximity Label-MS Homo sapiens
206 MRPL38  
Proximity Label-MS Homo sapiens
207 DLAT 1737
Proximity Label-MS Homo sapiens
208 METTL15  
Proximity Label-MS Homo sapiens
209 LYRM4 57128
Proximity Label-MS Homo sapiens
210 MRPL18 29074
Proximity Label-MS Homo sapiens
211 VWA8 23078
Proximity Label-MS Homo sapiens
212 C10orf2 56652
Proximity Label-MS Homo sapiens
213 PPIF 10105
Proximity Label-MS Homo sapiens
214 GBAS 2631
Co-fractionation Homo sapiens
215 NDUFA5 4698
Proximity Label-MS Homo sapiens
216 IMMT 10989
Proximity Label-MS Homo sapiens
217 AK4 205
Proximity Label-MS Homo sapiens
218 CLPP 8192
Proximity Label-MS Homo sapiens
219 DDX50 79009
Proximity Label-MS Homo sapiens
220 CS 1431
Proximity Label-MS Homo sapiens
221 GLS 2744
Proximity Label-MS Homo sapiens
222 C17orf80 55028
Proximity Label-MS Homo sapiens
223 MRPS7 51081
Proximity Label-MS Homo sapiens
224 TSFM 10102
Proximity Label-MS Homo sapiens
225 AUH 549
Co-crystal Structure Homo sapiens
Co-crystal Structure Homo sapiens
226 NDUFAF2  
Proximity Label-MS Homo sapiens
227 IDH3B 3420
Proximity Label-MS Homo sapiens
228 MRPS9 64965
Proximity Label-MS Homo sapiens
229 ALDH4A1 8659
Proximity Label-MS Homo sapiens
230 POLG  
Proximity Label-MS Homo sapiens
231 ATP5J 522
Proximity Label-MS Homo sapiens
232 MRPS2 51116
Proximity Label-MS Homo sapiens
233 COQ5  
Proximity Label-MS Homo sapiens
234 UQCC1 55245
Proximity Label-MS Homo sapiens
235 GTPBP6  
Proximity Label-MS Homo sapiens
236 ICT1 3396
Proximity Label-MS Homo sapiens
237 MRPS28  
Proximity Label-MS Homo sapiens
238 LARS2 23395
Proximity Label-MS Homo sapiens
239 HADH 3033
Proximity Label-MS Homo sapiens
240 MRPL53  
Proximity Label-MS Homo sapiens
241 BCKDHA 593
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
242 COX5A 9377
Proximity Label-MS Homo sapiens
243 PUS1 80324
Proximity Label-MS Homo sapiens
244 NDUFA12 55967
Proximity Label-MS Homo sapiens
245 PDHB 5162
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
246 PLOD1 5351
Proximity Label-MS Homo sapiens
247 MRPS10 55173
Proximity Label-MS Homo sapiens
248 NSA2  
Proximity Label-MS Homo sapiens
249 NUDT19 390916
Proximity Label-MS Homo sapiens
250 SHMT2 6472
Proximity Label-MS Homo sapiens
251 MRPS18C  
Proximity Label-MS Homo sapiens
252 RPS15A 6210
Proximity Label-MS Homo sapiens
253 GATC  
Proximity Label-MS Homo sapiens
254 PPA2 27068
Proximity Label-MS Homo sapiens
255 TRAP1 10131
Proximity Label-MS Homo sapiens
256 ME2 4200
Proximity Label-MS Homo sapiens
257 GUF1  
Proximity Label-MS Homo sapiens
258 NIPSNAP1 8508
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
259 LONP1 9361
Proximity Label-MS Homo sapiens
260 MRPS18B 28973
Proximity Label-MS Homo sapiens
261 GFM1 85476
Proximity Label-MS Homo sapiens
262 ALYREF 10189
Proximity Label-MS Homo sapiens
263 AARS2  
Proximity Label-MS Homo sapiens
264 MRPL13  
Proximity Label-MS Homo sapiens
265 TEFM  
Proximity Label-MS Homo sapiens
266 ACOT1 641371
Proximity Label-MS Homo sapiens
267 SDHA 6389
Proximity Label-MS Homo sapiens
268 MRPL46  
Proximity Label-MS Homo sapiens
269 FECH 2235
Proximity Label-MS Homo sapiens
270 THNSL1 79896
Proximity Label-MS Homo sapiens
271 MRPS16  
Proximity Label-MS Homo sapiens
272 GRSF1 2926
Proximity Label-MS Homo sapiens
273 NDUFAF4 29078
Proximity Label-MS Homo sapiens
274 QRSL1  
Proximity Label-MS Homo sapiens
275 NDUFS6  
Proximity Label-MS Homo sapiens
276 MRPL55  
Proximity Label-MS Homo sapiens
277 MRPS31  
Proximity Label-MS Homo sapiens
278 NDUFV2 4729
Proximity Label-MS Homo sapiens
279 MRPS22 56945
Proximity Label-MS Homo sapiens
280 SSRP1 6749
Proximity Label-MS Homo sapiens
281 FLAD1 80308
Proximity Label-MS Homo sapiens
282 MRPL28 10573
Proximity Label-MS Homo sapiens
283 TFAM 7019
Proximity Label-MS Homo sapiens
284 LUC7L 55692
Proximity Label-MS Homo sapiens
285 MRPS18A  
Proximity Label-MS Homo sapiens
286 MRPL43 84545
Proximity Label-MS Homo sapiens
287 DDX28  
Proximity Label-MS Homo sapiens
288 TIMM44 10469
Proximity Label-MS Homo sapiens
289 ECSIT 51295
Proximity Label-MS Homo sapiens
290 DARS2 55157
Proximity Label-MS Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here