ExoCarta: Gene summary

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Gene description for MRPL12
Gene name	mitochondrial ribosomal protein L12
Gene symbol	MRPL12
Other names/aliases	5c5-2 L12mt MRP-L31/34 MRPL7 MRPL7/L12 RPML12
Species	Homo sapiens
Database cross references - MRPL12
ExoCarta	ExoCarta_6182
Vesiclepedia	VP_6182
Entrez Gene	6182
HGNC	10378
MIM	602375
UniProt	P52815
MRPL12 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells	36408942
Bone marrow mesenchymal stem cells	36408942
Bone marrow mesenchymal stem cells	36408942
Bone marrow mesenchymal stem cells	36408942

Gene ontology annotations for MRPL12

Molecular Function
	RNA binding	GO:0003723	TAS
	mRNA binding	GO:0003729	IBA
	structural constituent of ribosome	GO:0003735	IBA
	protein binding	GO:0005515	IPI
Biological Process
	mitochondrial transcription	GO:0006390	IDA
	translation	GO:0006412	IBA
	mitochondrial translation	GO:0032543	NAS
	positive regulation of DNA-templated transcription	GO:0045893	IDA
Subcellular Localization
	mitochondrion	GO:0005739	HTP
	mitochondrion	GO:0005739	IDA
	mitochondrial inner membrane	GO:0005743	NAS
	mitochondrial inner membrane	GO:0005743	TAS
	mitochondrial matrix	GO:0005759	IDA
	mitochondrial matrix	GO:0005759	TAS
	mitochondrial large ribosomal subunit	GO:0005762	IBA
	mitochondrial large ribosomal subunit	GO:0005762	IDA
	mitochondrial large ribosomal subunit	GO:0005762	NAS

Experiment description of studies that identified MRPL12 in sEVs

Experiment ID

489

MISEV standards
✔ EM	Biophysical techniques
✔ Cd9\|Cd81\|Cd63\|Gapdh\|Sdcbp\|Lamp1\|Aqp1\|Rab5a\|Icam1\|Cd82\|Itga2b\|Tsg101\|Lamp2\|Rab35\|Flot1\|Flot2\|Cd151\|Rab5b\|Tfrc\|Uchl1	Enriched markers
✔ Canx	Negative markers
✔ NTA	Particle analysis

Identified molecule

Protein

Identification method

Mass spectrometry

PubMed ID

36408942

Organism

Rattus norvegicus

Experiment description

Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells

Authors

"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."

Journal name

Proteomics

Publication year

2023

Sample

Bone marrow mesenchymal stem cells

Sample name

BMSC - Passage 6

Isolation/purification methods

Differential centrifugation
Filtration
Ultracentrifugation

Flotation density

Molecules identified in the study

Protein

Methods used in the study

Western blotting
Mass spectometry

Experiment ID

490

MISEV standards
✔ EM	Biophysical techniques
✔ Cd9\|Cd81\|Cd63\|Gapdh\|Sdcbp\|Lamp1\|Aqp1\|Rab5a\|Icam1\|Cd82\|Itga2b\|Tsg101\|Lamp2\|Rab35\|Flot1\|Flot2\|Cd151\|Rab5b\|Tfrc\|Uchl1	Enriched markers
✔ Canx	Negative markers
✔ NTA	Particle analysis

Identified molecule

Protein

Identification method

Mass spectrometry

PubMed ID

36408942

Organism

Rattus norvegicus

Experiment description

Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells

Authors

"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."

Journal name

Proteomics

Publication year

2023

Sample

Bone marrow mesenchymal stem cells

Sample name

BMSC - Passage 7

Isolation/purification methods

Differential centrifugation
Filtration
Ultracentrifugation

Flotation density

Molecules identified in the study

Protein

Methods used in the study

Western blotting
Mass spectometry

Experiment ID

491

MISEV standards
✔ EM	Biophysical techniques
✔ Cd9\|Cd81\|Cd63\|Gapdh\|Sdcbp\|Lamp1\|Aqp1\|Rab5a\|Icam1\|Cd82\|Itga2b\|Tsg101\|Lamp2\|Rab35\|Flot1\|Flot2\|Cd151\|Rab5b\|Tfrc\|Uchl1	Enriched markers
✔ Canx	Negative markers
✔ NTA	Particle analysis

Identified molecule

Protein

Identification method

Mass spectrometry

PubMed ID

36408942

Organism

Rattus norvegicus

Experiment description

Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells

Authors

"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."

Journal name

Proteomics

Publication year

2023

Sample

Bone marrow mesenchymal stem cells

Sample name

BMSC - Passage 8

Isolation/purification methods

Differential centrifugation
Filtration
Ultracentrifugation

Flotation density

Molecules identified in the study

Protein

Methods used in the study

Western blotting
Mass spectometry

Experiment ID

492

MISEV standards
✔ EM	Biophysical techniques
✔ Cd9\|Cd81\|Cd63\|Gapdh\|Sdcbp\|Lamp1\|Aqp1\|Rab5a\|Icam1\|Cd82\|Itga2b\|Tsg101\|Lamp2\|Rab35\|Flot1\|Flot2\|Cd151\|Rab5b\|Tfrc\|Uchl1	Enriched markers
✔ Canx	Negative markers
✔ NTA	Particle analysis

Identified molecule

Protein

Identification method

Mass spectrometry

PubMed ID

36408942

Organism

Rattus norvegicus

Experiment description

Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells

Authors

"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."

Journal name

Proteomics

Publication year

2023

Sample

Bone marrow mesenchymal stem cells

Sample name

BMSC - Passage 9

Isolation/purification methods

Differential centrifugation
Filtration
Ultracentrifugation

Flotation density

Molecules identified in the study

Protein

Methods used in the study

Western blotting
Mass spectometry

Protein-protein interactions for MRPL12

Protein Interactor

ExoCarta ID

Identification method

PubMed

Species

SNRPB2

6629

Affinity Capture-MS

Homo sapiens

MINOS1-NBL1

Two-hybrid

Homo sapiens

MRPS27

23107

Affinity Capture-Western

Homo sapiens

PPP6R2

9701

Affinity Capture-MS

Homo sapiens

UBE2H

7328

Affinity Capture-MS

Homo sapiens

SLIRP

81892

Proximity Label-MS

Homo sapiens

TFB1M

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

MRPL48

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

HDAC2

3066

Affinity Capture-MS

Homo sapiens

BCKDK

10295

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

GTPBP8

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

NME6

Affinity Capture-MS

Homo sapiens

COX15

1355

Proximity Label-MS

Homo sapiens

MRPL33

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

RIT1

6016

Negative Genetic

Homo sapiens

TARDBP

23435

Affinity Capture-MS

Homo sapiens

ADRB2

Affinity Capture-MS

Homo sapiens

Ybx1

22608

Affinity Capture-MS

Mus musculus

ACTC1

Affinity Capture-MS

Homo sapiens

CD2AP

23607

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

MTG2

Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

NGRN

Proximity Label-MS

Homo sapiens

SEPT5

5413

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

CHCHD1

Proximity Label-MS

Homo sapiens

MRPL10

124995

Co-fractionation		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

MRPL27

51264

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

RPL14

9045

Co-fractionation

Homo sapiens

THOC7

80145

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

MRPL50

54534

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

HARS2

23438

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

CAND1

55832

Affinity Capture-MS

Homo sapiens

MRPL52

Affinity Capture-MS		Homo sapiens
Co-fractionation		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

MRRF

Proximity Label-MS

Homo sapiens

MRPL49

740

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

MRPL44

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

DNAJC15

Proximity Label-MS

Homo sapiens

MTRF1

Proximity Label-MS

Homo sapiens

GFM2

84340

Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

CORO1A

11151

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

CCDC90B

Proximity Label-MS

Homo sapiens

RPL26L1

51121

Affinity Capture-MS

Homo sapiens

SS18L2

Affinity Capture-MS

Homo sapiens

LRPPRC

10128

Proximity Label-MS

Homo sapiens

SEPT9

10801

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

TRUB2

Proximity Label-MS

Homo sapiens

DDX23

9416

Cross-Linking-MS (XL-MS)

Homo sapiens

MRPL22

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

RDX

5962

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

MCU

90550

Proximity Label-MS

Homo sapiens

YARS2

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

TFAM

7019

Proximity Label-MS

Homo sapiens

RBM3

5935

Co-fractionation		Homo sapiens
Affinity Capture-MS		Homo sapiens

PMPCA

23203

Proximity Label-MS

Homo sapiens

HINT2

84681

Proximity Label-MS

Homo sapiens

TRMT2B

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

PTPMT1

114971

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

MRPL23

6150

Co-fractionation		Homo sapiens
Affinity Capture-MS		Homo sapiens

H2AFV

94239

Cross-Linking-MS (XL-MS)

Homo sapiens

PRC1

9055

Affinity Capture-MS

Homo sapiens

C8orf82

Proximity Label-MS

Homo sapiens

RPL37A

6168

Cross-Linking-MS (XL-MS)

Homo sapiens

MRPL12

6182

Two-hybrid		Homo sapiens
Two-hybrid		Homo sapiens

SRRM2

23524

Affinity Capture-MS

Homo sapiens

RPS8

6202

Affinity Capture-MS

Homo sapiens

MRPL21

219927

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

EIF5B

9669

Affinity Capture-MS

Homo sapiens

OLIG1

Two-hybrid

Homo sapiens

CALM3

808

Affinity Capture-MS

Homo sapiens

MYCN

Affinity Capture-MS

Homo sapiens

MRPS26

64949

Proximity Label-MS		Homo sapiens
Co-fractionation		Homo sapiens

SURF1

Proximity Label-MS

Homo sapiens

EFCAB2

Two-hybrid

Homo sapiens

SEPT8

23176

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

EXD2

Proximity Label-MS

Homo sapiens

MRPL39

54148

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

SEPT7

989

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

CUL1

8454

Affinity Capture-MS

Homo sapiens

BTRC

8945

Affinity Capture-MS

Homo sapiens

SEPT1

1731

Two-hybrid

Homo sapiens

TACO1

Proximity Label-MS

Homo sapiens

FASTKD2

Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

KLF15

Affinity Capture-MS

Homo sapiens

THOC1

9984

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

VWA8

23078

Proximity Label-MS

Homo sapiens

MRPL47

57129

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

SOD1

6647

Affinity Capture-MS

Homo sapiens

RPL19

6143

Co-fractionation

Homo sapiens

MTERF3

Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

KIF14

9928

Affinity Capture-MS

Homo sapiens

GATB

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

TRIM59

Two-hybrid

Homo sapiens

PNPT1

87178

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

MDH2

4191

Proximity Label-MS

Homo sapiens

KLF16

Affinity Capture-MS

Homo sapiens

MRPS30

10884

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

CALM2

805

Affinity Capture-MS

Homo sapiens

MRPL13

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

UBE2N

7334

Affinity Capture-MS

Homo sapiens

MRPL57

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

100

C1orf122

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

101

MRPL32

64983

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

102

SLC25A10

1468

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

103

C6orf203

Proximity Label-MS

Homo sapiens

104

CMAS

55907

Affinity Capture-MS

Homo sapiens

105

MRPL17

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

106

RC3H2

Affinity Capture-MS

Homo sapiens

107

FASTKD5

Proximity Label-MS

Homo sapiens

108

MRPL45

84311

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

109

PARK2

Affinity Capture-MS

Homo sapiens

110

MALSU1

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

111

MRPL20

55052

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

112

MTFR1L

56181

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

113

MRPL14

64928

Affinity Capture-MS

Homo sapiens

114

POLRMT

5442

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

115

KRTAP10-1

Two-hybrid

Homo sapiens

116

PPP1R16A

84988

Two-hybrid

Homo sapiens

117

ARPP19

10776

Cross-Linking-MS (XL-MS)

Homo sapiens

118

TUFM

7284

Proximity Label-MS

Homo sapiens

119

CBX3

11335

Two-hybrid

Homo sapiens

120

HSCB

150274

Proximity Label-MS

Homo sapiens

121

WDYHV1

Two-hybrid

Homo sapiens

122

MRPL51

51258

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

123

MRPL46

Affinity Capture-MS

Homo sapiens

124

CCDC109B

55013

Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

125

HERC2

8924

Affinity Capture-MS

Homo sapiens

126

SMC3

9126

Cross-Linking-MS (XL-MS)

Homo sapiens

127

MRPL34

Affinity Capture-MS

Homo sapiens

128

TBRG4

9238

Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

129

KIAA0391

Affinity Capture-MS

Homo sapiens

130

MRPL3

Co-fractionation		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

131

FTSJ2

29960

Affinity Capture-MS

Homo sapiens

132

MTFMT

Proximity Label-MS

Homo sapiens

133

MRPL11

65003

Co-fractionation		Homo sapiens
Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

134

MTRF1L

Proximity Label-MS

Homo sapiens

135

THOC2

57187

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

136

SAT1

Two-hybrid

Homo sapiens

137

TMEM70

Proximity Label-MS

Homo sapiens

138

CYLD

Affinity Capture-MS

Homo sapiens

139

MRPL2

51069

Affinity Capture-MS

Homo sapiens

140

SEPT6

23157

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

141

RPL11

6135

Co-fractionation

Homo sapiens

142

NEURL4

Affinity Capture-MS

Homo sapiens

143

OXA1L

Affinity Capture-MS

Homo sapiens

144

DST

667

Cross-Linking-MS (XL-MS)

Homo sapiens

145

PA2G4

5036

Affinity Capture-MS

Homo sapiens

146

HNRNPD

3184

Co-fractionation

Homo sapiens

147

MRM1

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

148

YBX3

8531

Affinity Capture-MS

Homo sapiens

149

OTC

5009

Proximity Label-MS

Homo sapiens

150

MRPL40

64976

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

151

AK2

204

Co-fractionation

Homo sapiens

152

RPLP2

6181

Co-fractionation

Homo sapiens

153

MRPL54

Affinity Capture-MS

Homo sapiens

154

MRPS12

Proximity Label-MS

Homo sapiens

155

RPL23

9349

Co-fractionation

Homo sapiens

156

MTIF2

4528

Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

157

RPS2

6187

Co-fractionation

Homo sapiens

158

PITRM1

10531

Co-fractionation

Homo sapiens

159

MRPL24

Affinity Capture-MS

Homo sapiens

160

MRPL35

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

161

CLPP

8192

Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

162

MTIF3

Proximity Label-MS

Homo sapiens

163

SEPT3

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

164

MSI1

Affinity Capture-MS

Homo sapiens

165

MRPL9

65005

Co-fractionation		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

166

HIST1H1E

3008

Cross-Linking-MS (XL-MS)

Homo sapiens

167

MRPL16

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

168

EPPK1

83481

Co-fractionation

Homo sapiens

169

PRKCZ

5590

Affinity Capture-MS

Homo sapiens

170

MTG1

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

171

CUL3

8452

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

172

NR3C1

2908

Proximity Label-MS

Homo sapiens

173

RMND1

55005

Proximity Label-MS

Homo sapiens

174

PDIA3

2923

Affinity Capture-MS

Homo sapiens

175

THOC5

8563

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

176

GADD45GIP1

Co-fractionation		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

177

DHX30

22907

Proximity Label-MS

Homo sapiens

178

MORF4L1

Two-hybrid

Homo sapiens

179

PPP6R3

55291

Affinity Capture-MS

Homo sapiens

180

SEL1L

6400

Affinity Capture-MS

Homo sapiens

181

TXNDC9

10190

Two-hybrid

Homo sapiens

182

C17orf80

55028

Proximity Label-MS

Homo sapiens

183

MRPL15

29088

Co-fractionation		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

184

ECI2

10455

Affinity Capture-MS

Homo sapiens

185

MRPL1

Co-fractionation		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

186

PMPCB

9512

Proximity Label-MS

Homo sapiens

187

MAP7D1

55700

Affinity Capture-MS

Homo sapiens

188

SEPT2

4735

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

189

SOAT1

6646

Affinity Capture-MS

Homo sapiens

190

MRPL4

51073

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

191

MRPL30

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

192

RPUSD4

84881

Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

193

MYC

Affinity Capture-MS

Homo sapiens

194

FOXP2

93986

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

195

SDR39U1

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

196

MRPL37

51253

Co-fractionation		Homo sapiens
Affinity Capture-MS		Homo sapiens

197

DLST

1743

Affinity Capture-MS

Homo sapiens

198

TSFM

10102

Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

199

RPL12

6136

Co-fractionation

Homo sapiens

200

TMEM9

252839

Co-fractionation

Homo sapiens

201

ACAD9

28976

Proximity Label-MS

Homo sapiens

202

NTM

50863

Two-hybrid

Homo sapiens

203

SND1

27044

Affinity Capture-MS

Homo sapiens

204

RPL18

6141

Co-fractionation

Homo sapiens

205

DDRGK1

65992

Affinity Capture-MS

Homo sapiens

206

VDAC1

7416

Affinity Capture-MS

Homo sapiens

207

RNASET2

Co-fractionation

Homo sapiens

208

SEPT11

55752

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

209

MSN

4478

Affinity Capture-MS

Homo sapiens

210

YBX1

4904

Affinity Capture-MS

Homo sapiens

211

MRPL38

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

212

PUS1

80324

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

213

FOXP4

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

214

METTL15

Proximity Label-MS

Homo sapiens

215

MTERF2

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

216

SH3KBP1

30011

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

217

MCUR1

63933

Proximity Label-MS

Homo sapiens

218

MRPL18

29074

Affinity Capture-MS

Homo sapiens

219

RARG

Two-hybrid

Homo sapiens

220

GOLGB1

2804

Cross-Linking-MS (XL-MS)

Homo sapiens

221

NIT2

56954

Co-fractionation

Homo sapiens

222

NIPSNAP3A

Affinity Capture-MS

Homo sapiens

223

XRCC1

7515

Co-fractionation

Homo sapiens

224

DNAJC19

131118

Proximity Label-MS

Homo sapiens

225

1431

Proximity Label-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

226

MRPL42

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Co-fractionation		Homo sapiens

227

CEP290

Cross-Linking-MS (XL-MS)

Homo sapiens

228

PLEKHA4

57664

Affinity Capture-MS

Homo sapiens

229

GIGYF2

26058

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

230

METTL17

Proximity Label-MS

Homo sapiens

231

AUH

549

Proximity Label-MS

Homo sapiens

232

ILF3

3609

Co-fractionation

Homo sapiens

233

RAB11FIP5

26056

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

234

NBL1

4681

Two-hybrid

Homo sapiens

235

FBXL6

Affinity Capture-MS

Homo sapiens

236

GPI

2821

Affinity Capture-MS

Homo sapiens

237

GTPBP6

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

238

ICT1

3396

Affinity Capture-MS		Homo sapiens
Co-fractionation		Homo sapiens
Affinity Capture-Western		Homo sapiens
Affinity Capture-Western		Homo sapiens
Co-fractionation		Homo sapiens
Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

239

MRPS28

Co-fractionation

Homo sapiens

240

SUCLG2

8801

Co-fractionation

Homo sapiens

241

LONP1

9361

Proximity Label-MS

Homo sapiens

242

CENPJ

55835

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

243

PHF3

Cross-Linking-MS (XL-MS)

Homo sapiens

244

EZR

7430

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

245

MRPL53

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Cross-Linking-MS (XL-MS)		Homo sapiens
Cross-Linking-MS (XL-MS)		Homo sapiens

246

LSM14A

26065

Affinity Capture-MS

Homo sapiens

247

MRPL43

84545

Affinity Capture-MS

Homo sapiens

248

PDHA1

5160

Proximity Label-MS

Homo sapiens

249

DNAJA3

9093

Proximity Label-MS

Homo sapiens

250

SEPT10

151011

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

251

C12orf65

Proximity Label-MS

Homo sapiens

252

MORF4L2

Two-hybrid

Homo sapiens

253

OXNAD1

92106

Affinity Capture-MS

Homo sapiens

254

COX8A

Proximity Label-MS

Homo sapiens

255

SUCLA2

8803

Co-fractionation

Homo sapiens

256

OS9

10956

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

257

C21orf33

Proximity Label-MS

Homo sapiens

258

ELMO2

63916

Cross-Linking-MS (XL-MS)

Homo sapiens

259

SSBP1

6742

Proximity Label-MS

Homo sapiens

260

MTERF4

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

261

TRAP1

10131

Affinity Capture-MS

Homo sapiens

262

UFL1

23376

Affinity Capture-MS

Homo sapiens

263

FASTKD3

Proximity Label-MS

Homo sapiens

264

CEP131

22994

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

265

IDH2

3418

Affinity Capture-MS

Homo sapiens

266

PREPL

9581

Affinity Capture-MS

Homo sapiens

267

MRPL41

64975

Co-fractionation		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

268

GFM1

85476

Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

269

AARS2

Proximity Label-MS

Homo sapiens

270

ACOX1

Co-fractionation

Homo sapiens

271

H2AFZ

3015

Cross-Linking-MS (XL-MS)

Homo sapiens

272

TEFM

Proximity Label-MS

Homo sapiens

273

MRPS9

64965

Co-fractionation

Homo sapiens

274

RPL7A

6130

Co-fractionation

Homo sapiens

275

MRPL19

9801

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

276

ANXA5

308

Affinity Capture-MS

Homo sapiens

277

RPUSD3

Proximity Label-MS

Homo sapiens

278

GRSF1

2926

Proximity Label-MS

Homo sapiens

279

C1QBP

708

Affinity Capture-MS		Homo sapiens
Proximity Label-MS		Homo sapiens

280

EXOC3L2

Two-hybrid

Homo sapiens

281

KRAS

3845

Negative Genetic

Homo sapiens

282

POLR1D

51082

Two-hybrid

Homo sapiens

283

MRPL55

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

284

RC3H1

149041

Affinity Capture-MS

Homo sapiens

285

ACSF2

80221

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

286

DARS2

55157

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

287

COX6A2

Two-hybrid

Homo sapiens

288

MRPL28

10573

Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

289

MRPS18A

Affinity Capture-MS

Homo sapiens

290

DDX28

Proximity Label-MS		Homo sapiens
Affinity Capture-MS		Homo sapiens

291

UFM1

51569

Co-fractionation

Homo sapiens

292

EFEMP2

30008

Two-hybrid

Homo sapiens

View the network

Pathways in which MRPL12 is involved

Pathway	Evidence	Source
Metabolism of proteins	TAS	Reactome
Metabolism of proteins	IEA	Reactome
Mitochondrial protein degradation	TAS	Reactome
Mitochondrial translation	TAS	Reactome
Mitochondrial translation	IEA	Reactome
Mitochondrial translation elongation	TAS	Reactome
Mitochondrial translation elongation	IEA	Reactome
Mitochondrial translation initiation	IEA	Reactome
Mitochondrial translation termination	TAS	Reactome
Translation	TAS	Reactome
Translation	IEA	Reactome

Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here