Gene description for CENPE
Gene name	centromere protein E, 312kDa
Gene symbol	CENPE
Other names/aliases	CENP-E KIF10 MCPH13 PPP1R61
Species	Homo sapiens
Database cross references - CENPE
ExoCarta	ExoCarta_1062
Vesiclepedia	VP_1062
Entrez Gene	1062
HGNC	1856
MIM	117143
UniProt	Q02224
CENPE identified in sEVs derived from the following tissue/cell type
Neuroblastoma cells	25944692
Prostate cancer cells	25844599

Gene ontology annotations for CENPE

Molecular Function     microtubule motor activity GO:0003777 IDA     microtubule motor activity GO:0003777 IMP     protein binding GO:0005515 IPI     ATP binding GO:0005524 IEA     microtubule binding GO:0008017 IBA     microtubule binding GO:0008017 IDA     kinetochore binding GO:0043515 IDA Biological Process     mitotic cell cycle GO:0000278 IBA     mitotic cell cycle GO:0000278 IMP     microtubule-based movement GO:0007018 IBA     mitotic spindle organization GO:0007052 IMP     chromosome segregation GO:0007059 IMP     mitotic chromosome movement towards spindle pole GO:0007079 IDA     mitotic metaphase chromosome alignment GO:0007080 IMP     regulation of mitotic metaphase/anaphase transition GO:0030071 IMP     positive regulation of protein kinase activity GO:0045860 IMP     cell division GO:0051301 IEA     metaphase chromosome alignment GO:0051310 IMP     attachment of mitotic spindle microtubules to kinetochore GO:0051315 IMP     kinetochore assembly GO:0051382 IDA     microtubule plus-end directed mitotic chromosome migration GO:0099606 IDA     lateral attachment of mitotic spindle microtubules to kinetochore GO:0099607 IMP Subcellular Localization     chromosome, centromeric region GO:0000775 IDA     kinetochore GO:0000776 IDA     condensed chromosome, centromeric region GO:0000779 IDA     nucleus GO:0005634 IMP     chromosome GO:0005694 IDA     kinetochore microtubule GO:0005828 IDA     cytosol GO:0005829 TAS     microtubule GO:0005874 IBA     microtubule GO:0005874 IDA     microtubule cytoskeleton GO:0015630 IDA     membrane GO:0016020 HDA     midbody GO:0030496 IDA     intracellular membrane-bounded organelle GO:0043231 IDA     intercellular bridge GO:0045171 IDA     spindle midzone GO:0051233 IDA     mitotic spindle GO:0072686 IDA     mitotic spindle midzone GO:1990023 IDA