Gene description for AGR3
Gene name anterior gradient 3
Gene symbol AGR3
Other names/aliases AG-3
AG3
BCMP11
HAG3
PDIA18
hAG-3
Species Homo sapiens
 Database cross references - AGR3
ExoCarta ExoCarta_155465
Vesiclepedia VP_155465
Entrez Gene 155465
HGNC 24167
MIM 609482
UniProt Q8TD06  
 AGR3 identified in sEVs derived from the following tissue/cell type
Colorectal cancer cells 17956143    
 Gene ontology annotations for AGR3
Molecular Function
    dystroglycan binding GO:0002162 IBA
    dystroglycan binding GO:0002162 IDA
    protein binding GO:0005515 IPI
Subcellular Localization
    endoplasmic reticulum GO:0005783 IBA
    endoplasmic reticulum GO:0005783 IDA
    intracellular membrane-bounded organelle GO:0043231 IDA
 Experiment description of studies that identified AGR3 in sEVs
1
Experiment ID 20
MISEV standards
EM
Biophysical techniques
HSP90|CD63|CD81|LAMP1
Enriched markers
GOLGA2|cytochrome c
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17956143    
Organism Homo sapiens
Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer cells.
Authors "Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS"
Journal name JPR
Publication year 2007
Sample Colorectal cancer cells
Sample name HT29
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Diafiltration
Flotation density 1.16 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for AGR3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 LYPD3 27076
Two-hybrid Homo sapiens
2 KRTAP11-1  
Two-hybrid Homo sapiens
3 LSM1 27257
Two-hybrid Homo sapiens
4 ERLIN1 10613
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
5 DAG1 1605
Two-hybrid Homo sapiens
6 UBQLN2 29978
Two-hybrid Homo sapiens
7 NUP62 23636
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
8 SPINT1 6692
Two-hybrid Homo sapiens
9 TMEM14B  
Two-hybrid Homo sapiens
10 NRM 11270
Two-hybrid Homo sapiens
11 MMGT1 93380
Two-hybrid Homo sapiens
12 SGTB  
Two-hybrid Homo sapiens
13 CNNM3 26505
Two-hybrid Homo sapiens
14 EDA2R  
Two-hybrid Homo sapiens
15 BAG1 573
Affinity Capture-MS Homo sapiens
16 WDYHV1  
Two-hybrid Homo sapiens
17 ASB10  
Two-hybrid Homo sapiens
18 TIMMDC1  
Two-hybrid Homo sapiens
19 SERBP1 26135
Affinity Capture-MS Homo sapiens
20 PDZK1IP1 10158
Two-hybrid Homo sapiens
21 LIME1 54923
Two-hybrid Homo sapiens
22 SGTA 6449
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
23 PRAF2 11230
Two-hybrid Homo sapiens
24 UBQLN1 29979
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
25 CD46 4179
Two-hybrid Homo sapiens
26 CATSPER1  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which AGR3 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here