Gene description for Rps17
Gene name ribosomal protein S17
Gene symbol Rps17
Other names/aliases -
Species Mus musculus
 Database cross references - Rps17
ExoCarta ExoCarta_20068
Vesiclepedia VP_20068
Entrez Gene 20068
UniProt P63276  
 Rps17 identified in sEVs derived from the following tissue/cell type
Colon cancer cells 37309723    
Mast cells 17486113    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Rps17
Molecular Function
    structural constituent of ribosome GO:0003735 IDA
    structural constituent of ribosome GO:0003735 ISO
Biological Process
    cytoplasmic translation GO:0002181 NAS
    rRNA processing GO:0006364 ISO
    translation GO:0006412 ISO
    erythrocyte homeostasis GO:0034101 ISO
    ribosomal small subunit biogenesis GO:0042274 ISO
    ribosomal small subunit biogenesis GO:0042274 ISS
Subcellular Localization
    nucleolus GO:0005730 IEA
    cytoplasm GO:0005737 NAS
    cytosol GO:0005829 TAS
    ribosome GO:0005840 NAS
    cytosolic ribosome GO:0022626 ISO
    cytosolic small ribosomal subunit GO:0022627 IDA
    cytosolic small ribosomal subunit GO:0022627 ISO
    cytosolic small ribosomal subunit GO:0022627 NAS
    small-subunit processome GO:0032040 ISO
    small-subunit processome GO:0032040 ISS
    synapse GO:0045202 EXP
    synapse GO:0045202 IDA
    postsynapse GO:0098794 NAS
 Experiment description of studies that identified Rps17 in sEVs
1
Experiment ID 907
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 15
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
3
Experiment ID 15
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
4
Experiment ID 908
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Rps17
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Rps27a 78294
Co-fractionation Mus musculus
2 Rps3 27050
Co-fractionation Mus musculus
3 Rpl11 67025
Co-fractionation Mus musculus
4 Rpl24 68193
Co-fractionation Mus musculus
5 Rps10 67097
Co-fractionation Mus musculus
6 Eif5a 276770
Co-fractionation Mus musculus
7 Cnbp 12785
Co-fractionation Mus musculus
8 Rplp2 67186
Co-fractionation Mus musculus
9 Gnb2l1 14694
Co-fractionation Mus musculus
10 Rps4x 20102
Co-fractionation Mus musculus
11 Rpl14 67115
Co-fractionation Mus musculus
12 Rps2 16898
Co-fractionation Mus musculus
13 Pkm 18746
Co-fractionation Mus musculus
14 Rpl7a 27176
Co-fractionation Mus musculus
15 Rpl3 27367
Co-fractionation Mus musculus
16 Rpl32 19951
Co-fractionation Mus musculus
17 Rpl6 19988
Co-fractionation Mus musculus
18 Kctd13  
Affinity Capture-MS Mus musculus
19 Rps19 20085
Co-fractionation Mus musculus
20 Tfe3  
Affinity Capture-MS Mus musculus
21 Vcp 269523
Co-fractionation Mus musculus
22 Tpt1 22070
Co-fractionation Mus musculus
23 Rps11 27207
Co-fractionation Mus musculus
24 Rpl18a 76808
Co-fractionation Mus musculus
25 Rps5 20103
Co-fractionation Mus musculus
26 Rps7 20115
Co-fractionation Mus musculus
27 Rpl22 19934
Co-fractionation Mus musculus
28 Fzr1  
Affinity Capture-MS Mus musculus
29 Tardbp 230908
Co-fractionation Mus musculus
30 Eef2 13629
Co-fractionation Mus musculus
31 Rpl7 19989
Co-fractionation Mus musculus
32 Eef1a1 13627
Co-fractionation Mus musculus
33 Rps21 66481
Co-fractionation Mus musculus
34 Rps15a 267019
Co-fractionation Mus musculus
35 Actg1 11465
Co-fractionation Mus musculus
36 Rps15 20054
Co-fractionation Mus musculus
37 Rpl18 19899
Co-fractionation Mus musculus
38 Rps3a1 20091
Co-fractionation Mus musculus
39 Nudc 18221
Co-fractionation Mus musculus
40 Rpl26 19941
Co-fractionation Mus musculus
41 Fancd2  
Affinity Capture-MS Mus musculus
42 Rplp0 11837
Co-fractionation Mus musculus
43 Rpl23a 268449
Co-fractionation Mus musculus
44 Pgk1 18655
Co-fractionation Mus musculus
45 Rpl35 66489
Co-fractionation Mus musculus
46 Rpsa 16785
Co-fractionation Mus musculus
47 Eef1b2 55949
Co-fractionation Mus musculus
48 Tpi1 21991
Co-fractionation Mus musculus
49 Rpl5 100503670
Co-fractionation Mus musculus
50 Rpl13 270106
Co-fractionation Mus musculus
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here