Gene description for DPY19L1
Gene name dpy-19-like 1 (C. elegans)
Gene symbol DPY19L1
Other names/aliases -
Species Homo sapiens
 Database cross references - DPY19L1
ExoCarta ExoCarta_23333
Vesiclepedia VP_23333
Entrez Gene 23333
HGNC 22205
MIM 613892
UniProt Q2PZI1  
 DPY19L1 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for DPY19L1
Molecular Function
    mannosyltransferase activity GO:0000030 IBA
Biological Process
    protein glycosylation GO:0006486 IEA
Subcellular Localization
    endoplasmic reticulum membrane GO:0005789 IBA
    membrane GO:0016020 HDA
 Experiment description of studies that identified DPY19L1 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for DPY19L1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RPA2 6118
Proximity Label-MS Homo sapiens
2 LDLRAD4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 LYPD3 27076
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 IFNLR1  
Affinity Capture-MS Homo sapiens
5 CYB5B 80777
Affinity Capture-MS Homo sapiens
6 ATP13A3 79572
Affinity Capture-MS Homo sapiens
7 APLNR  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 GPR45  
Affinity Capture-MS Homo sapiens
9 TTYH1  
Affinity Capture-MS Homo sapiens
10 CANX 821
Affinity Capture-MS Homo sapiens
11 TP53 7157
Affinity Capture-MS Homo sapiens
12 GP9 2815
Affinity Capture-MS Homo sapiens
13 TNFRSF8 943
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
14 OPALIN  
Affinity Capture-MS Homo sapiens
15 CD79B 974
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 IGDCC4  
Affinity Capture-MS Homo sapiens
17 LRRC55  
Affinity Capture-MS Homo sapiens
18 CHST8 64377
Affinity Capture-MS Homo sapiens
19 SLC1A1 6505
Affinity Capture-MS Homo sapiens
20 CMKLR1 1240
Affinity Capture-MS Homo sapiens
21 CRELD1 78987
Affinity Capture-MS Homo sapiens
22 HS2ST1 9653
Affinity Capture-MS Homo sapiens
23 CHST5  
Affinity Capture-MS Homo sapiens
24 COX15 1355
Affinity Capture-MS Homo sapiens
25 CD70 970
Affinity Capture-MS Homo sapiens
26 CLEC4E  
Affinity Capture-MS Homo sapiens
27 BTN3A3 10384
Affinity Capture-MS Homo sapiens
28 SLC24A3  
Affinity Capture-MS Homo sapiens
29 ISG15 9636
Affinity Capture-MS Homo sapiens
30 SLC22A9  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
31 THBS2 7058
Affinity Capture-MS Homo sapiens
32 COQ2  
Affinity Capture-MS Homo sapiens
33 CHRNB2  
Affinity Capture-MS Homo sapiens
34 CYS1 192668
Affinity Capture-MS Homo sapiens
35 HEATR3 55027
Affinity Capture-MS Homo sapiens
36 PBXIP1 57326
Affinity Capture-MS Homo sapiens
37 SEC62 7095
Proximity Label-MS Homo sapiens
38 ATP2A1 487
Proximity Label-MS Homo sapiens
39 SEMA7A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 TCTN2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
41 LIME1 54923
Affinity Capture-MS Homo sapiens
42 RPN1 6184
Proximity Label-MS Homo sapiens
43 VIPR1  
Affinity Capture-MS Homo sapiens
44 SCNN1D  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
45 VDAC1 7416
Affinity Capture-MS Homo sapiens
46 TMEM184A  
Affinity Capture-MS Homo sapiens
47 CD3E 916
Affinity Capture-MS Homo sapiens
48 UPK1A 11045
Affinity Capture-MS Homo sapiens
49 PIGH  
Affinity Capture-MS Homo sapiens
50 RPA3 6119
Proximity Label-MS Homo sapiens
51 SCN3B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
52 ATP2A3 489
Affinity Capture-MS Homo sapiens
53 C1orf95  
Affinity Capture-MS Homo sapiens
54 C3orf52  
Affinity Capture-MS Homo sapiens
55 CDRT15  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
56 AVPR2  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which DPY19L1 is involved
No pathways found





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