Gene description for ATP2A3
Gene name	ATPase, Ca++ transporting, ubiquitous
Gene symbol	ATP2A3
Other names/aliases	SERCA3
Species	Homo sapiens
Database cross references - ATP2A3
ExoCarta	ExoCarta_489
Vesiclepedia	VP_489
Entrez Gene	489
HGNC	813
MIM	601929
UniProt	Q93084
ATP2A3 identified in sEVs derived from the following tissue/cell type
Platelets	25332113
Platelets	25332113
Platelets	25332113
Squamous carcinoma cells	20124223
Thymus	23844026

Gene ontology annotations for ATP2A3

Molecular Function     P-type calcium transporter activity GO:0005388 IBA     P-type calcium transporter activity GO:0005388 IDA     P-type calcium transporter activity GO:0005388 TAS     protein binding GO:0005515 IPI     ATP binding GO:0005524 IEA     cysteine-type endopeptidase activator activity involved in apoptotic process GO:0008656 IDA     calcium ion transmembrane transporter activity GO:0015085 IDA     ATP hydrolysis activity GO:0016887 IEA     calcium-dependent ATPase activity GO:0030899 IDA     transmembrane transporter binding GO:0044325 IPI     metal ion binding GO:0046872 IEA Biological Process     calcium ion transport GO:0006816 TAS     intracellular calcium ion homeostasis GO:0006874 IBA     intracellular calcium ion homeostasis GO:0006874 IMP     monoatomic ion transmembrane transport GO:0034220 TAS     intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 IDA     calcium ion transmembrane transport GO:0070588 IBA     calcium ion transmembrane transport GO:0070588 IDA     transport across blood-brain barrier GO:0150104 NAS     negative regulation of receptor binding GO:1900121 IMP     calcium ion transport from cytosol to endoplasmic reticulum GO:1903515 IDA     regulation of cardiac conduction GO:1903779 TAS Subcellular Localization     endoplasmic reticulum GO:0005783 IDA     endoplasmic reticulum membrane GO:0005789 TAS     membrane GO:0016020 IBA     sarcoplasmic reticulum GO:0016529 IDA     organelle membrane GO:0031090 IDA     platelet dense tubular network membrane GO:0031095 TAS     nuclear membrane GO:0031965 IEA     sarcoplasmic reticulum membrane GO:0033017 IEA