Gene description for NCBP1
Gene name nuclear cap binding protein subunit 1, 80kDa
Gene symbol NCBP1
Other names/aliases CBP80
NCBP
Sto1
Species Homo sapiens
 Database cross references - NCBP1
ExoCarta ExoCarta_4686
Vesiclepedia VP_4686
Entrez Gene 4686
HGNC 7658
MIM 600469
UniProt Q09161  
 NCBP1 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 34887515    
Endothelial cells 26027894    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Mesenchymal stem cells 36408942    
Squamous carcinoma cells 20124223    
Thymus 23844026    
 Gene ontology annotations for NCBP1
Molecular Function
    RNA cap binding GO:0000339 IBA
    RNA 7-methylguanosine cap binding GO:0000340 IMP
    RNA binding GO:0003723 HDA
    mRNA binding GO:0003729 IBA
    protein binding GO:0005515 IPI
    molecular adaptor activity GO:0060090 EXP
Biological Process
    nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 IBA
    nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 IDA
    nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 IMP
    nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 NAS
    spliceosomal complex assembly GO:0000245 IMP
    alternative mRNA splicing, via spliceosome GO:0000380 NAS
    mRNA splicing, via spliceosome GO:0000398 NAS
    cap-dependent translational initiation GO:0002191 NAS
    7-methylguanosine mRNA capping GO:0006370 IDA
    RNA catabolic process GO:0006401 IMP
    mRNA export from nucleus GO:0006406 IBA
    mRNA export from nucleus GO:0006406 IMP
    mRNA export from nucleus GO:0006406 IPI
    snRNA export from nucleus GO:0006408 IMP
    snRNA export from nucleus GO:0006408 NAS
    regulation of translational initiation GO:0006446 IDA
    histone mRNA metabolic process GO:0008334 IMP
    RNA splicing GO:0008380 TAS
    mRNA metabolic process GO:0016071 IMP
    positive regulation of cell growth GO:0030307 IMP
    primary miRNA processing GO:0031053 NAS
    mRNA 3'-end processing GO:0031124 NAS
    positive regulation of mRNA 3'-end processing GO:0031442 IMP
    positive regulation of transcription elongation by RNA polymerase II GO:0032968 NAS
    regulatory ncRNA-mediated post-transcriptional gene silencing GO:0035194 NAS
    miRNA-mediated post-transcriptional gene silencing GO:0035195 NAS
    mRNA transcription by RNA polymerase II GO:0042789 IDA
    mRNA transcription by RNA polymerase II GO:0042789 NAS
    positive regulation of mRNA splicing, via spliceosome GO:0048026 IMP
    regulation of mRNA processing GO:0050684 IBA
    defense response to virus GO:0051607 IMP
    positive regulation of RNA binding GO:1905216 IMP
Subcellular Localization
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IDA
    nucleoplasm GO:0005654 TAS
    cytoplasm GO:0005737 IDA
    cytoplasm GO:0005737 NAS
    mitochondrion GO:0005739 IDA
    cytosol GO:0005829 IDA
    cytosol GO:0005829 TAS
    nuclear cap binding complex GO:0005846 IBA
    nuclear cap binding complex GO:0005846 IDA
    nuclear cap binding complex GO:0005846 IPI
    RNA cap binding complex GO:0034518 IMP
    RNA cap binding complex GO:0034518 TAS
    ribonucleoprotein complex GO:1990904 IDA
 Experiment description of studies that identified NCBP1 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
8
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
11
Experiment ID 226
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD9|FLOT1
Enriched markers
✔
LMNA|H2AFX|ATP5A1|TOMM20
Negative markers
✘ Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description "Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting"
Authors "Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar"
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
12
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
15
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
16
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
17
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for NCBP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 MVP 9961
Co-fractionation Homo sapiens
2 HNRNPH1 3187
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
3 KPNA6 23633
Affinity Capture-MS Homo sapiens
4 RIT1 6016
Negative Genetic Homo sapiens
5 CPSF6 11052
Affinity Capture-MS Homo sapiens
6 UBE2H 7328
Affinity Capture-MS Homo sapiens
7 HNRNPC 3183
Affinity Capture-MS Homo sapiens
8 Tmed2 56334
Affinity Capture-MS Mus musculus
9 Myh3  
Affinity Capture-MS Mus musculus
10 KIF23 9493
Affinity Capture-MS Homo sapiens
11 SERPINE2 5270
Co-fractionation Homo sapiens
12 POLDIP3 84271
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
13 KPNA3 3839
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
14 UBL4A 8266
Affinity Capture-MS Homo sapiens
15 Smc1a  
Affinity Capture-MS Mus musculus
16 GART 2618
Affinity Capture-MS Homo sapiens
17 ZNF346  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 KPNA1 3836
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 TRRAP 8295
Affinity Capture-MS Homo sapiens
20 MTOR 2475
Affinity Capture-Western Homo sapiens
21 TARDBP 23435
Affinity Capture-MS Homo sapiens
22 YWHAE 7531
Affinity Capture-MS Homo sapiens
23 HIST1H2BG 8339
Proximity Label-MS Homo sapiens
24 THOC2 57187
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
25 GNS 2799
Co-fractionation Homo sapiens
26 WDR76  
Affinity Capture-MS Homo sapiens
27 KIF20A 10112
Affinity Capture-MS Homo sapiens
28 RNMT 8731
Co-fractionation Homo sapiens
29 HNRNPCL1 343069
Affinity Capture-MS Homo sapiens
30 CAND1 55832
Affinity Capture-MS Homo sapiens
31 HNRNPR 10236
Co-fractionation Homo sapiens
32 PTPN1 5770
Co-fractionation Homo sapiens
33 SENP3 26168
Affinity Capture-MS Homo sapiens
34 EIF4E2  
Co-fractionation Homo sapiens
35 SNRPD2 6633
Affinity Capture-MS Homo sapiens
36 HSPA5 3309
Co-fractionation Homo sapiens
37 HSF2  
Affinity Capture-MS Homo sapiens
38 CUL4B 8450
Affinity Capture-RNA Homo sapiens
39 LRPPRC 10128
Co-fractionation Homo sapiens
40 RPS9 6203
Co-fractionation Homo sapiens
41 CAPZB 832
Co-fractionation Homo sapiens
42 TROVE2 6738
Co-fractionation Homo sapiens
43 SNRNP70 6625
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
44 NCBP1 4686
Affinity Capture-RNA Homo sapiens
Affinity Capture-RNA Homo sapiens
45 FERMT3 83706
Affinity Capture-MS Homo sapiens
46 PRC1 9055
Affinity Capture-MS Homo sapiens
47 SSRP1 6749
Affinity Capture-MS Homo sapiens
48 GFPT1 2673
Co-fractionation Homo sapiens
49 SF3B1 23451
Affinity Capture-MS Homo sapiens
50 THOC6 79228
Affinity Capture-MS Homo sapiens
51 BRAT1 221927
Affinity Capture-MS Homo sapiens
52 SPAG9 9043
Co-fractionation Homo sapiens
53 EIF3B 8662
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
54 COPS5 10987
Affinity Capture-MS Homo sapiens
55 Cep85l  
Affinity Capture-MS Mus musculus
56 ERC1 23085
Co-fractionation Homo sapiens
57 SNRPC 6631
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
58 PSMB6 5694
Co-fractionation Homo sapiens
59 OBSL1 23363
Affinity Capture-MS Homo sapiens
60 BOD1L1 259282
Affinity Capture-MS Homo sapiens
61 GSPT1 2935
Co-fractionation Homo sapiens
62 RSRC1  
Affinity Capture-MS Homo sapiens
63 PGD 5226
Co-fractionation Homo sapiens
64 EED  
Affinity Capture-MS Homo sapiens
65 NUPL2 11097
Affinity Capture-MS Homo sapiens
66 ATG16L1 55054
Affinity Capture-MS Homo sapiens
67 MPP1 4354
Affinity Capture-MS Homo sapiens
68 NAP1L4 4676
Co-fractionation Homo sapiens
69 MECP2 4204
Affinity Capture-MS Homo sapiens
70 CUL1 8454
Affinity Capture-MS Homo sapiens
71 MYCN  
Affinity Capture-MS Homo sapiens
72 RBM42  
Affinity Capture-MS Homo sapiens
73 Klc3  
Affinity Capture-MS Mus musculus
74 THOC1 9984
Affinity Capture-MS Homo sapiens
75 RBM8A 9939
Affinity Capture-MS Homo sapiens
76 HSPA8 3312
Co-fractionation Homo sapiens
77 LIN28A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
78 UNK  
Affinity Capture-RNA Homo sapiens
79 GARS 2617
Co-fractionation Homo sapiens
80 E2F4  
Affinity Capture-MS Homo sapiens
81 ZDHHC17 23390
Two-hybrid Homo sapiens
82 SF3A2 8175
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
83 POLD1 5424
Affinity Capture-MS Homo sapiens
84 FOXA1  
Affinity Capture-MS Homo sapiens
85 EIF4G1 1981
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
86 DDX21 9188
Affinity Capture-MS Homo sapiens
87 LIN28B  
Affinity Capture-MS Homo sapiens
88 BNIP1 662
Two-hybrid Homo sapiens
89 RBM47 54502
Affinity Capture-MS Homo sapiens
90 RB1CC1 9821
Affinity Capture-MS Homo sapiens
91 PARK2  
Affinity Capture-MS Homo sapiens
92 RBM6 10180
Affinity Capture-MS Homo sapiens
93 PHAX  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
94 SUPT5H 6829
Affinity Capture-MS Homo sapiens
95 SNRPA 6626
Affinity Capture-MS Homo sapiens
96 C17orf85  
Two-hybrid Homo sapiens
Affinity Capture-RNA Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-RNA Homo sapiens
97 RBM7  
Affinity Capture-MS Homo sapiens
98 Smc3 13006
Affinity Capture-MS Mus musculus
99 SRRT 51593
Affinity Capture-MS Homo sapiens
100 KPNA4 3840
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
101 RPS6KB1 6198
Affinity Capture-Western Homo sapiens
102 CCNB1 891
Affinity Capture-MS Homo sapiens
103 PABPC1 26986
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
104 NELFE 7936
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
105 RPA2 6118
Co-fractionation Homo sapiens
106 BARD1 580
Affinity Capture-MS Homo sapiens
107 ACTN4 81
Co-fractionation Homo sapiens
108 NTRK1 4914
Affinity Capture-MS Homo sapiens
109 U2AF2 11338
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
110 RAD18  
Affinity Capture-MS Homo sapiens
111 ZSCAN26  
Affinity Capture-MS Homo sapiens
112 NELFB 25920
Affinity Capture-MS Homo sapiens
113 NCL 4691
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
114 ARRDC3 57561
Affinity Capture-MS Homo sapiens
115 KPNB1 3837
Affinity Capture-MS Homo sapiens
116 LETMD1  
Affinity Capture-MS Homo sapiens
117 LYAR 55646
Affinity Capture-MS Homo sapiens
118 PML 5371
Affinity Capture-MS Homo sapiens
119 DHX9 1660
Affinity Capture-MS Homo sapiens
120 HECTD1 25831
Affinity Capture-MS Homo sapiens
121 APOL2 23780
Affinity Capture-MS Homo sapiens
122 RPLP0 6175
Co-fractionation Homo sapiens
123 DDX39B 7919
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
124 PPM1G 5496
Co-fractionation Homo sapiens
125 Ncbp2  
Affinity Capture-MS Mus musculus
126 RAN 5901
Affinity Capture-MS Homo sapiens
127 POLR2B 5431
Affinity Capture-MS Homo sapiens
128 ELAVL2 1993
Affinity Capture-MS Homo sapiens
129 PAIP2B  
Affinity Capture-MS Homo sapiens
130 TJP1 7082
Cross-Linking-MS (XL-MS) Homo sapiens
131 RNF40 9810
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
132 VAT1 10493
Co-fractionation Homo sapiens
133 RBM39 9584
Affinity Capture-MS Homo sapiens
134 SYNCRIP 10492
Co-fractionation Homo sapiens
135 IPO5 3843
Co-fractionation Homo sapiens
136 PRPF4B 8899
Affinity Capture-MS Homo sapiens
137 C11orf57  
Affinity Capture-MS Homo sapiens
138 NFIC 4782
Affinity Capture-MS Homo sapiens
139 XPO1 7514
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
140 RC3H2  
Affinity Capture-MS Homo sapiens
141 ECT2 1894
Affinity Capture-MS Homo sapiens
142 Dennd6a  
Affinity Capture-MS Mus musculus
143 SIRT7  
Affinity Capture-MS Homo sapiens
144 NELFCD 51497
Affinity Capture-MS Homo sapiens
145 SNRPB 6628
Affinity Capture-MS Homo sapiens
146 PTPRA 5786
Affinity Capture-MS Homo sapiens
147 CERK 64781
Affinity Capture-MS Homo sapiens
148 AP1M1 8907
Affinity Capture-MS Homo sapiens
149 CUL3 8452
Affinity Capture-MS Homo sapiens
150 BNIP2  
Two-hybrid Homo sapiens
151 GEMIN2 8487
Affinity Capture-MS Homo sapiens
152 HSD17B10 3028
Affinity Capture-MS Homo sapiens
153 THOC5 8563
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
154 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
155 FUS 2521
Affinity Capture-MS Homo sapiens
156 RBM27  
Co-fractionation Homo sapiens
157 EPRS 2058
Co-fractionation Homo sapiens
158 MYC  
Affinity Capture-MS Homo sapiens
159 SUZ12  
Affinity Capture-MS Homo sapiens
160 FN1 2335
Affinity Capture-MS Homo sapiens
161 NCBP2 22916
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-RNA Homo sapiens
Affinity Capture-MS Homo sapiens
Co-crystal Structure Homo sapiens
Co-crystal Structure Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-RNA Homo sapiens
Affinity Capture-Western Homo sapiens
162 SF3A1 10291
Affinity Capture-MS Homo sapiens
163 PRMT5 10419
Co-fractionation Homo sapiens
164 PCBP1 5093
Affinity Capture-MS Homo sapiens
165 TADA2A  
Affinity Capture-MS Homo sapiens
166 EIF4E 1977
Co-fractionation Homo sapiens
167 PSPC1 55269
Affinity Capture-MS Homo sapiens
168 Uso1 56041
Affinity Capture-MS Mus musculus
169 Tpx2  
Affinity Capture-MS Mus musculus
170 ZC3H18  
Affinity Capture-MS Homo sapiens
171 RPRD2  
Affinity Capture-MS Homo sapiens
172 DAZL  
Affinity Capture-MS Homo sapiens
173 STKLD1  
Co-fractionation Homo sapiens
174 TOP1 7150
Affinity Capture-MS Homo sapiens
175 HSPA1A 3303
Co-fractionation Homo sapiens
176 NFKB1 4790
Co-fractionation Homo sapiens
177 SKIV2L2 23517
Affinity Capture-MS Homo sapiens
178 UPF3B 65109
Affinity Capture-Western Homo sapiens
179 DDRGK1 65992
Affinity Capture-MS Homo sapiens
180 RNF2  
Affinity Capture-MS Homo sapiens
181 BMI1  
Affinity Capture-MS Homo sapiens
182 BNIP3 664
Two-hybrid Homo sapiens
183 CSDE1 7812
Co-fractionation Homo sapiens
184 SNRPF 6636
Affinity Capture-MS Homo sapiens
185 HSPA9 3313
Co-fractionation Homo sapiens
186 PUS1 80324
Co-fractionation Homo sapiens
187 GCN1L1 10985
Affinity Capture-MS Homo sapiens
188 C9orf72  
Affinity Capture-MS Homo sapiens
189 NAA10 8260
Co-fractionation Homo sapiens
190 HUWE1 10075
Affinity Capture-MS Homo sapiens
191 PPP2R1B 5519
Affinity Capture-MS Homo sapiens
192 PAIP1 10605
Affinity Capture-MS Homo sapiens
193 GRK5 2869
Affinity Capture-MS Homo sapiens
194 SNCA 6622
Affinity Capture-MS Homo sapiens
195 PRMT3 10196
Co-fractionation Homo sapiens
196 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
197 Tubg1 103733
Affinity Capture-MS Mus musculus
198 TTC1 7265
Co-fractionation Homo sapiens
199 DDX20 11218
Affinity Capture-MS Homo sapiens
200 IMPDH2 3615
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
201 Sod1 20655
Affinity Capture-MS Mus musculus
202 SEC23IP 11196
Co-fractionation Homo sapiens
203 STX3 6809
Cross-Linking-MS (XL-MS) Homo sapiens
204 THOC3  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
205 APOBEC3D  
Affinity Capture-MS Homo sapiens
206 SNRPA1 6627
Affinity Capture-MS Homo sapiens
207 DDX3X 1654
Affinity Capture-Western Homo sapiens
208 SRSF9 8683
Affinity Capture-MS Homo sapiens
209 CUL5 8065
Affinity Capture-MS Homo sapiens
210 PDHA1 5160
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
211 SMURF1 57154
Affinity Capture-MS Homo sapiens
212 SMAD4  
Affinity Capture-RNA Homo sapiens
213 NELFA  
Affinity Capture-MS Homo sapiens
214 SNX2 6643
Co-fractionation Homo sapiens
215 RNF20 56254
Two-hybrid Homo sapiens
216 EIF4A3 9775
Co-fractionation Homo sapiens
217 KPNA2 3838
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
218 PPRC1  
Affinity Capture-MS Homo sapiens
219 PSMA1 5682
Co-fractionation Homo sapiens
220 DYNC1H1 1778
Co-fractionation Homo sapiens
221 UFL1 23376
Affinity Capture-MS Homo sapiens
222 SNIP1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
223 PSTPIP1 9051
Two-hybrid Homo sapiens
224 GAPDH 2597
Co-fractionation Homo sapiens
225 ALYREF 10189
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
226 HNRNPL 3191
Co-fractionation Homo sapiens
227 GSPT2 23708
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
228 UPF1 5976
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
229 MYPOP  
Cross-Linking-MS (XL-MS) Homo sapiens
230 CIT 11113
Affinity Capture-MS Homo sapiens
231 CTIF  
Co-fractionation Homo sapiens
232 HNRNPF 3185
Reconstituted Complex Homo sapiens
233 SERBP1 26135
Affinity Capture-MS Homo sapiens
234 SNW1 22938
Affinity Capture-MS Homo sapiens
235 KRAS 3845
Negative Genetic Homo sapiens
236 SLBP  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
237 RC3H1 149041
Affinity Capture-MS Homo sapiens
238 IVNS1ABP  
Affinity Capture-MS Homo sapiens
239 RPS3 6188
Co-fractionation Homo sapiens
240 RPA3 6119
Proximity Label-MS Homo sapiens
241 LUC7L 55692
Affinity Capture-MS Homo sapiens
242 EP300 2033
Affinity Capture-MS Homo sapiens
243 HNRNPA2B1 3181
Co-fractionation Homo sapiens
244 DYNC1LI2 1783
Co-fractionation Homo sapiens
View the network image/svg+xml
 Pathways in which NCBP1 is involved
PathwayEvidenceSource
Abortive elongation of HIV-1 transcript in the absence of Tat IEA Reactome
Axon guidance IEA Reactome
Developmental Biology IEA Reactome
Disease IEA Reactome
Diseases of signal transduction by growth factor receptors and second messengers IEA Reactome
FGFR2 alternative splicing TAS Reactome
FGFR2 mutant receptor activation IEA Reactome
Formation of HIV elongation complex in the absence of HIV Tat IEA Reactome
Formation of HIV-1 elongation complex containing HIV-1 Tat IEA Reactome
Formation of RNA Pol II elongation complex TAS Reactome
Formation of the Early Elongation Complex TAS Reactome
Formation of the HIV-1 Early Elongation Complex IEA Reactome
Gene expression (Transcription) TAS Reactome
HIV Infection IEA Reactome
HIV Life Cycle IEA Reactome
HIV Transcription Elongation IEA Reactome
Infectious disease IEA Reactome
Late Phase of HIV Life Cycle IEA Reactome
Metabolism of non-coding RNA TAS Reactome
Metabolism of RNA TAS Reactome
mRNA 3'-end processing TAS Reactome
mRNA Capping TAS Reactome
mRNA Splicing TAS Reactome
mRNA Splicing - Major Pathway TAS Reactome
mRNA Splicing - Minor Pathway TAS Reactome
Nervous system development IEA Reactome
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) TAS Reactome
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) TAS Reactome
Nonsense-Mediated Decay (NMD) TAS Reactome
Processing of Capped Intron-Containing Pre-mRNA TAS Reactome
Processing of Capped Intronless Pre-mRNA TAS Reactome
Processing of Intronless Pre-mRNAs TAS Reactome
Regulation of expression of SLITs and ROBOs IEA Reactome
RNA Polymerase II Pre-transcription Events TAS Reactome
RNA polymerase II transcribes snRNA genes TAS Reactome
RNA Polymerase II Transcription TAS Reactome
RNA Polymerase II Transcription Elongation TAS Reactome
RNA Polymerase II Transcription Termination TAS Reactome
Signal Transduction TAS Reactome
Signaling by FGFR TAS Reactome
Signaling by FGFR in disease IEA Reactome
Signaling by FGFR2 TAS Reactome
Signaling by FGFR2 IIIa TM IEA Reactome
Signaling by FGFR2 in disease IEA Reactome
Signaling by Receptor Tyrosine Kinases TAS Reactome
Signaling by ROBO receptors IEA Reactome
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs TAS Reactome
SLBP independent Processing of Histone Pre-mRNAs TAS Reactome
snRNP Assembly TAS Reactome
Tat-mediated elongation of the HIV-1 transcript IEA Reactome
Transcription of the HIV genome IEA Reactome
Transport of Mature mRNA derived from an Intron-Containing Transcript TAS Reactome
Transport of Mature mRNA Derived from an Intronless Transcript TAS Reactome
Transport of Mature mRNAs Derived from Intronless Transcripts TAS Reactome
Transport of Mature Transcript to Cytoplasm TAS Reactome
Transport of the SLBP Dependant Mature mRNA TAS Reactome
Transport of the SLBP independent Mature mRNA TAS Reactome
Viral Infection Pathways IEA Reactome





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