Gene description for TTC27
Gene name tetratricopeptide repeat domain 27
Gene symbol TTC27
Other names/aliases -
Species Homo sapiens
 Database cross references - TTC27
ExoCarta ExoCarta_55622
Vesiclepedia VP_55622
Entrez Gene 55622
HGNC 25986
UniProt Q6P3X3  
 TTC27 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Mesenchymal stem cells 36408942    
Thymus 23844026    
 Gene ontology annotations for TTC27
Molecular Function
    protein binding GO:0005515 IPI
 Experiment description of studies that identified TTC27 in sEVs
1
Experiment ID 489
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 488
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 217
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for TTC27
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TXLNA 200081
Co-fractionation Homo sapiens
2 UPK2 7379
Affinity Capture-MS Homo sapiens
3 DHX15 1665
Co-fractionation Homo sapiens
4 UFD1L 7353
Co-fractionation Homo sapiens
5 RIT1 6016
Negative Genetic Homo sapiens
6 EAPP  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 KLK15  
Affinity Capture-MS Homo sapiens
8 FAF2 23197
Affinity Capture-MS Homo sapiens
9 CCT3 7203
Affinity Capture-MS Homo sapiens
10 CSTF1 1477
Co-fractionation Homo sapiens
11 CCT5 22948
Affinity Capture-MS Homo sapiens
12 Prpf8 192159
Affinity Capture-MS Mus musculus
13 VIPR1  
Affinity Capture-MS Homo sapiens
14 GFPT1 2673
Co-fractionation Homo sapiens
15 KLK5 25818
Affinity Capture-MS Homo sapiens
16 TTC27 55622
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 ECD  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 ASNS 440
Co-fractionation Homo sapiens
19 PHLDA3 23612
Affinity Capture-MS Homo sapiens
20 CCT6A 908
Affinity Capture-MS Homo sapiens
21 CSNK1A1 1452
Affinity Capture-MS Homo sapiens
22 ZNHIT2 741
Affinity Capture-MS Homo sapiens
23 TRIM66  
Affinity Capture-MS Homo sapiens
24 OPALIN  
Affinity Capture-MS Homo sapiens
25 CD2AP 23607
Co-fractionation Homo sapiens
26 EFTUD2 9343
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 MGARP  
Affinity Capture-MS Homo sapiens
28 MAPK3 5595
Co-fractionation Homo sapiens
29 CUL3 8452
Affinity Capture-MS Homo sapiens
30 PRPF8 10594
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
31 CCT4 10575
Affinity Capture-MS Homo sapiens
32 EGFR 1956
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
33 CTDP1 9150
Affinity Capture-MS Homo sapiens
34 RUVBL2 10856
Affinity Capture-MS Homo sapiens
35 AAR2 25980
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
36 FBXO6 26270
Affinity Capture-MS Homo sapiens
37 TSSC4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
38 MFSD4  
Affinity Capture-MS Homo sapiens
39 ASXL1  
Affinity Capture-MS Homo sapiens
40 NCDN 23154
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
41 FBXL12 54850
Affinity Capture-MS Homo sapiens
42 CCT7 10574
Affinity Capture-MS Homo sapiens
43 ILVBL 10994
Affinity Capture-MS Homo sapiens
44 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
45 VSIG4  
Affinity Capture-MS Homo sapiens
46 GZMH  
Affinity Capture-MS Homo sapiens
47 KIAA1429 25962
Affinity Capture-MS Homo sapiens
48 SNRNP200 23020
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
49 DTNBP1  
Affinity Capture-MS Homo sapiens
50 PTP4A3  
Affinity Capture-MS Homo sapiens
51 MYC  
Affinity Capture-MS Homo sapiens
52 RPA2 6118
Proximity Label-MS Homo sapiens
53 NTRK1 4914
Affinity Capture-MS Homo sapiens
54 PPP2R5D 5528
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
55 HLA-B 3106
Affinity Capture-MS Homo sapiens
56 GPR182  
Affinity Capture-MS Homo sapiens
57 CCT2 10576
Affinity Capture-MS Homo sapiens
58 TMEM9 252839
Affinity Capture-MS Homo sapiens
59 SKIV2L2 23517
Co-fractionation Homo sapiens
60 NMD3 51068
Co-fractionation Homo sapiens
61 DHFRL1  
Affinity Capture-MS Homo sapiens
62 KRAS 3845
Synthetic Growth Defect Homo sapiens
Negative Genetic Homo sapiens
63 SCD 6319
Affinity Capture-MS Homo sapiens
64 C9orf72  
Affinity Capture-MS Homo sapiens
65 DDRGK1 65992
Affinity Capture-MS Homo sapiens
66 CSTF2 1478
Co-fractionation Homo sapiens
67 P2RY8  
Affinity Capture-MS Homo sapiens
68 RPA3 6119
Proximity Label-MS Homo sapiens
69 C10orf76  
Co-fractionation Homo sapiens
70 TCP1 6950
Affinity Capture-MS Homo sapiens
71 DNAJC12  
Affinity Capture-MS Homo sapiens
72 S1PR4  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which TTC27 is involved
No pathways found





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