Gene description for PAK6
Gene name	p21 protein (Cdc42/Rac)-activated kinase 6
Gene symbol	PAK6
Other names/aliases	PAK5
Species	Homo sapiens
Database cross references - PAK6
ExoCarta	ExoCarta_56924
Vesiclepedia	VP_56924
Entrez Gene	56924
HGNC	16061
MIM	608110
UniProt	Q9NQU5
PAK6 identified in sEVs derived from the following tissue/cell type
Colorectal cancer cells	23161513
Colorectal cancer cells	23161513
Colorectal cancer cells	23161513
Hepatocytes	26054723

Gene ontology annotations for PAK6

Molecular Function     protein serine/threonine kinase activity GO:0004674 IBA     3-phosphoinositide-dependent protein kinase activity GO:0004676 IEA     DNA-dependent protein kinase activity GO:0004677 IEA     AMP-activated protein kinase activity GO:0004679 IEA     eukaryotic translation initiation factor 2alpha kinase activity GO:0004694 IEA     ribosomal protein S6 kinase activity GO:0004711 IEA     protein binding GO:0005515 IPI     ATP binding GO:0005524 IEA     histone H3S10 kinase activity GO:0035175 IEA     histone H3T11 kinase activity GO:0035402 IEA     histone H3T6 kinase activity GO:0035403 IEA     histone H2AXS139 kinase activity GO:0035979 IEA     histone H3S28 kinase activity GO:0044022 IEA     histone H4S1 kinase activity GO:0044023 IEA     histone H2AS1 kinase activity GO:0044024 IEA     histone H2BS14 kinase activity GO:0044025 IEA     cadherin binding GO:0045296 HDA     histone H3T3 kinase activity GO:0072354 IEA     histone H2AS121 kinase activity GO:0072371 IEA     Rho-dependent protein serine/threonine kinase activity GO:0072518 IEA     protein serine kinase activity GO:0106310 IEA     histone H2BS36 kinase activity GO:0140823 IEA     histone H3S57 kinase activity GO:0140855 IEA     histone H3T45 kinase activity GO:0140857 IEA     histone H2AT120 kinase activity GO:1990244 IEA Biological Process     chromatin remodeling GO:0006338 IEA     regulation of DNA-templated transcription GO:0006355 TAS     apoptotic process GO:0006915 TAS     cytoskeleton organization GO:0007010 TAS     learning GO:0007612 IEA     memory GO:0007613 IEA     locomotory behavior GO:0007626 IEA     cellular response to starvation GO:0009267 IBA     intracellular signal transduction GO:0035556 IBA     regulation of MAPK cascade GO:0043408 IBA     neuron projection arborization GO:0140058 IEA     neuron projection extension GO:1990138 IEA Subcellular Localization     fibrillar center GO:0001650 IDA     nucleoplasm GO:0005654 IDA     cytoplasm GO:0005737 IBA     cytosol GO:0005829 TAS     postsynaptic density GO:0014069 IEA     cell junction GO:0030054 IDA