Gene description for CDH1
Gene name	cadherin 1, type 1, E-cadherin (epithelial)
Gene symbol	CDH1
Other names/aliases	Arc-1 CD324 CDHE ECAD LCAM UVO
Species	Homo sapiens
Database cross references - CDH1
ExoCarta	ExoCarta_999
Vesiclepedia	VP_999
Entrez Gene	999
HGNC	1748
MIM	192090
UniProt	P12830
CDH1 identified in sEVs derived from the following tissue/cell type
Colorectal cancer cells	17956143
Colorectal cancer cells	23161513
Colorectal cancer cells	23161513
Colorectal cancer cells	23161513
Colorectal cancer cells	25890246
Colorectal cancer cells	25890246
Keratinocytes	19530224
Keratinocytes	19530224
Ovarian cancer cells	23333927
Ovarian cancer cells	23333927
Prostate cancer cells	25844599

Gene ontology annotations for CDH1

Molecular Function     calcium ion binding GO:0005509 IEA     protein binding GO:0005515 IPI     beta-catenin binding GO:0008013 IBA     beta-catenin binding GO:0008013 IDA     beta-catenin binding GO:0008013 IPI     ankyrin binding GO:0030506 IPI     GTPase activating protein binding GO:0032794 IPI     identical protein binding GO:0042802 IPI     gamma-catenin binding GO:0045295 IPI     cadherin binding GO:0045296 HDA     cadherin binding GO:0045296 IBA     cell adhesion molecule binding GO:0050839 IPI     cell adhesion molecule binding GO:0050839 NAS     protein tyrosine kinase binding GO:1990782 IEA Biological Process     cell morphogenesis GO:0000902 IBA     cell-cell junction assembly GO:0007043 IBA     homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 NAS     synapse assembly GO:0007416 IBA     response to xenobiotic stimulus GO:0009410 IEA     response to toxic substance GO:0009636 IEA     regulation of gene expression GO:0010468 IMP     calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules GO:0016339 IBA     cell migration GO:0016477 IBA     pituitary gland development GO:0021983 IEA     negative regulation of cell-cell adhesion GO:0022408 IMP     negative regulation of cell migration GO:0030336 IMP     negative regulation of axon extension GO:0030517 IEA     neuron projection development GO:0031175 IEA     adherens junction organization GO:0034332 IBA     adherens junction organization GO:0034332 IMP     positive regulation of protein import into nucleus GO:0042307 IDA     cell-cell adhesion mediated by cadherin GO:0044331 IBA     cell-cell adhesion mediated by cadherin GO:0044331 IDA     positive regulation of DNA-templated transcription GO:0045893 IDA     cellular response to lithium ion GO:0071285 IDA     response to heparin GO:0071503 IEA     cellular response to indole-3-methanol GO:0071681 IDA     protein localization to plasma membrane GO:0072659 IDA     protein localization to plasma membrane GO:0072659 IMP     cell-cell adhesion GO:0098609 IDA     regulation of protein catabolic process at postsynapse, modulating synaptic transmission GO:0099576 IEA     response to Gram-positive bacterium GO:0140459 IEA Subcellular Localization     extracellular region GO:0005576 TAS     cytoplasm GO:0005737 IBA     cytoplasm GO:0005737 IDA     endosome GO:0005768 IEA     trans-Golgi network GO:0005802 IMP     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 TAS     adherens junction GO:0005912 IBA     adherens junction GO:0005912 IDA     cytoplasmic side of plasma membrane GO:0009898 IDA     actin cytoskeleton GO:0015629 IDA     membrane GO:0016020 IDA     lateral plasma membrane GO:0016328 IDA     catenin complex GO:0016342 IBA     catenin complex GO:0016342 IDA     flotillin complex GO:0016600 IBA     flotillin complex GO:0016600 IDA     lamellipodium GO:0030027 IDA     cell junction GO:0030054 IDA     cell junction GO:0030054 TAS     desmosome GO:0030057 IEA     cortical actin cytoskeleton GO:0030864 IDA     apical junction complex GO:0043296 IBA     apical junction complex GO:0043296 IDA     perinuclear region of cytoplasm GO:0048471 IDA     extracellular exosome GO:0070062 HDA     postsynapse GO:0098794 IEA     glutamatergic synapse GO:0098978 IEA