Experiment description of studies that identified PCDH1 in sEVs

1 Experiment ID 1203 MISEV standards ✔ Biophysical techniques ✔ Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 34887515     Organism Homo sapiens Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ." Journal name Nat Cell Biol Publication year 2021 Sample Colorectal cancer cells Sample name DiFi Isolation/purification methods Differential centrifugation Filtration Centrifugal ultrafiltration Ultracentrifugation OptiPrep density gradient centrifugation Flotation density - Molecules identified in the study Protein miRNA Methods used in the study Western blotting Mass spectrometry RNA sequencing

2 Experiment ID 224 MISEV standards ✔ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25944692     Organism Homo sapiens Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S" Journal name Oncotarget Publication year 2015 Sample Neuroblastoma cells Sample name SH-SY5Y Isolation/purification methods Differential centrifugation Ultracentrifugation OptiPrep density gradient Flotation density 1.10 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting

Protein-protein interactions for PCDH1

Protein Interactor ExoCarta ID Identification method PubMed Species 1 LY86   Affinity Capture-MS Homo sapiens 2 KIR3DL1   Affinity Capture-MS Homo sapiens 3 UPK2 7379 Affinity Capture-MS Homo sapiens 4 SSFA2 6744 Affinity Capture-MS Homo sapiens 5 GPM6A 2823 Affinity Capture-MS Homo sapiens 6 PCDHGA4   Affinity Capture-MS Homo sapiens 7 RAET1E   Affinity Capture-MS Homo sapiens 8 FCGR1A   Affinity Capture-MS Homo sapiens 9 CD200R1 131450 Affinity Capture-MS Homo sapiens 10 IL13RA2 3598 Affinity Capture-MS Homo sapiens 11 GTF3C3 9330 Affinity Capture-MS Homo sapiens 12 ZNFX1 57169 Affinity Capture-MS Homo sapiens 13 LILRB4   Affinity Capture-MS Homo sapiens 14 PCDHB7   Affinity Capture-MS Homo sapiens 15 MCAM 4162 Proximity Label-MS Homo sapiens 16 PCDH20   Affinity Capture-MS Homo sapiens 17 LPPR2   Affinity Capture-MS Homo sapiens 18 ICAM2 3384 Affinity Capture-MS Homo sapiens 19 MICA 100507436 Affinity Capture-MS Homo sapiens 20 FCGRT 2217 Affinity Capture-MS Homo sapiens 21 CDH8   Affinity Capture-MS Homo sapiens 22 CD4 920 Affinity Capture-MS Homo sapiens 23 ALB 213 Affinity Capture-MS Homo sapiens 24 ST8SIA2   Affinity Capture-MS Homo sapiens 25 RYK 6259 Affinity Capture-MS Homo sapiens 26 PRG2   Affinity Capture-MS Homo sapiens 27 SPSB4   Affinity Capture-MS Homo sapiens 28 IFNE   Affinity Capture-MS Homo sapiens 29 CLEC4A   Affinity Capture-MS Homo sapiens 30 CWF19L2   Affinity Capture-MS Homo sapiens 31 CEACAM21   Affinity Capture-MS Homo sapiens 32 SPSB2   Affinity Capture-MS Homo sapiens 33 LRRN4CL 221091 Affinity Capture-MS Homo sapiens 34 IL20   Affinity Capture-MS Homo sapiens 35 SPACA1 81833 Affinity Capture-MS Homo sapiens 36 IL1R2   Affinity Capture-MS Homo sapiens 37 PDCD1LG2 80380 Affinity Capture-MS Homo sapiens 38 VSIG4   Affinity Capture-MS Homo sapiens 39 CD48 962 Affinity Capture-MS Homo sapiens 40 ITGA5 3678 Affinity Capture-MS Homo sapiens 41 CDH1 999 Proximity Label-MS Homo sapiens 42 CORT   Affinity Capture-MS Homo sapiens 43 SDF2L1 23753 Affinity Capture-MS Homo sapiens 44 CRLF1 9244 Affinity Capture-MS Homo sapiens 45 ARL4D   Affinity Capture-MS Homo sapiens 46 DBI 1622 Affinity Capture-MS Homo sapiens 47 CD160   Affinity Capture-MS Homo sapiens 48 NXPH2   Affinity Capture-MS Homo sapiens 49 SMAD3 4088 Two-hybrid Homo sapiens 50 SGCA   Affinity Capture-MS Homo sapiens 51 FLRT1   Affinity Capture-MS Homo sapiens 52 VKORC1 79001 Two-hybrid Homo sapiens 53 TRIB1 10221 Affinity Capture-MS Homo sapiens 54 PVR 5817 Affinity Capture-MS Homo sapiens 55 NXPH3   Affinity Capture-MS Homo sapiens 56 CD70 970 Affinity Capture-MS Homo sapiens 57 CBLN4   Affinity Capture-MS Homo sapiens 58 GPX7 2882 Affinity Capture-MS Homo sapiens 59 ABCA2 20 Affinity Capture-MS Homo sapiens 60 NXPH1   Affinity Capture-MS Homo sapiens 61 SRP14 6727 Affinity Capture-MS Homo sapiens 62 PCDHA11   Affinity Capture-MS Homo sapiens 63 ICOS   Affinity Capture-MS Homo sapiens 64 CDH12   Affinity Capture-MS Homo sapiens 65 PRSS22 64063 Affinity Capture-MS Homo sapiens 66 TMPRSS11A   Affinity Capture-MS Homo sapiens 67 DKKL1   Affinity Capture-MS Homo sapiens View the network

Pathways in which PCDH1 is involved

No pathways found