Gene description for SRP14
Gene name signal recognition particle 14kDa (homologous Alu RNA binding protein)
Gene symbol SRP14
Other names/aliases ALURBP
Species Homo sapiens
 Database cross references - SRP14
ExoCarta ExoCarta_6727
Vesiclepedia VP_6727
Entrez Gene 6727
HGNC 11299
MIM 600708
UniProt P37108  
 SRP14 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 35918900    
Breast cancer cells 35918900    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Prostate cancer cells 25844599    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
Squamous carcinoma cells 20124223    
T lymphocytes 34108659    
Thymus 23844026    
 Gene ontology annotations for SRP14
Molecular Function
    RNA binding GO:0003723 HDA
    protein binding GO:0005515 IPI
    7S RNA binding GO:0008312 IEA
    endoplasmic reticulum signal peptide binding GO:0030942 IEA
Biological Process
    cotranslational protein targeting to membrane GO:0006613 TAS
    SRP-dependent cotranslational protein targeting to membrane GO:0006614 IEA
    protein targeting to ER GO:0045047 IBA
    protein targeting to ER GO:0045047 IMP
Subcellular Localization
    extracellular region GO:0005576 TAS
    nucleus GO:0005634 IDA
    cytoplasm GO:0005737 TAS
    signal recognition particle, endoplasmic reticulum targeting GO:0005786 IBA
    signal recognition particle, endoplasmic reticulum targeting GO:0005786 IDA
    cytosol GO:0005829 TAS
    secretory granule lumen GO:0034774 TAS
    ficolin-1-rich granule lumen GO:1904813 TAS
 Experiment description of studies that identified SRP14 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 1333
MISEV standards
Biophysical techniques
✔
CD81|EPCAM|CD9
Enriched markers
✘ Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35918900    
Organism Homo sapiens
Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
Authors "Bauzá-Martinez J, Armony G, Pronker MF, Wu W. "
Journal name J Extracell Vesicles
Publication year 2022
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectometry
Western blotting
10
Experiment ID 1335
MISEV standards
Biophysical techniques
✔
EPCAM|CD9
Enriched markers
✘ Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35918900    
Organism Homo sapiens
Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
Authors "Bauzá-Martinez J, Armony G, Pronker MF, Wu W. "
Journal name J Extracell Vesicles
Publication year 2022
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectometry
11
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
12
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
13
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
17
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
18
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
19
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
20
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
21
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
22
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
23
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
26
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
29
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
30
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
32
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
33
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
34
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
35
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
36
Experiment ID 274
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel resistant
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Flow cytometry
Western blotting
37
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
38
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
39
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
40
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
41
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SRP14
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CBS 875
Co-fractionation Homo sapiens
2 UBE2H 7328
Affinity Capture-MS Homo sapiens
3 CDC14B 8555
Affinity Capture-MS Homo sapiens
4 TLE1 7088
Affinity Capture-MS Homo sapiens
5 RIT1 6016
Negative Genetic Homo sapiens
6 RPSAP58 388524
Affinity Capture-MS Homo sapiens
7 MRPS25 64432
Affinity Capture-MS Homo sapiens
8 SENP3 26168
Affinity Capture-MS Homo sapiens
9 RPL26L1 51121
Affinity Capture-MS Homo sapiens
10 NPLOC4 55666
Co-fractionation Homo sapiens
11 NOLC1 9221
Co-fractionation Homo sapiens
12 MRPS22 56945
Affinity Capture-MS Homo sapiens
13 AATF  
Affinity Capture-MS Homo sapiens
14 DNAJC8 22826
Proximity Label-MS Homo sapiens
15 DDX24 57062
Affinity Capture-MS Homo sapiens
16 PTMA 5757
Affinity Capture-MS Homo sapiens
17 USP13  
Affinity Capture-MS Homo sapiens
18 KIAA0020 9933
Affinity Capture-MS Homo sapiens
19 PKM 5315
Co-fractionation Homo sapiens
20 MRPS27 23107
Affinity Capture-MS Homo sapiens
21 TOP3B 8940
Affinity Capture-MS Homo sapiens
22 BTF3 689
Affinity Capture-MS Homo sapiens
23 AKAP11 11215
Affinity Capture-MS Homo sapiens
24 DNAJA4 55466
Proximity Label-MS Homo sapiens
25 DNAJB2 3300
Proximity Label-MS Homo sapiens
26 L3HYPDH 112849
Affinity Capture-MS Homo sapiens
27 SOX2  
Affinity Capture-MS Homo sapiens
28 NOP56 10528
Affinity Capture-MS Homo sapiens
29 RPL10 6134
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
30 KIF20A 10112
Affinity Capture-MS Homo sapiens
31 PPAN-P2RY11  
Affinity Capture-MS Homo sapiens
32 RPL14 9045
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
33 LAMP2 3920
Co-fractionation Homo sapiens
34 CALM1 801
Reconstituted Complex Homo sapiens
35 CAND1 55832
Affinity Capture-MS Homo sapiens
36 RSBN1  
Affinity Capture-MS Homo sapiens
37 MAK16  
Affinity Capture-MS Homo sapiens
38 LTN1 26046
Affinity Capture-MS Homo sapiens
39 SNRPD2 6633
Co-fractionation Homo sapiens
40 MPHOSPH10 10199
Affinity Capture-MS Homo sapiens
41 RPS3 6188
Affinity Capture-MS Homo sapiens
42 USP36  
Affinity Capture-MS Homo sapiens
43 ZNF70  
Affinity Capture-MS Homo sapiens
44 Rrp1b 72462
Affinity Capture-MS Mus musculus
45 WTAP 9589
Affinity Capture-MS Homo sapiens
46 GYG1 2992
Affinity Capture-MS Homo sapiens
47 HIST1H2BD 3017
Affinity Capture-MS Homo sapiens
48 IGF2BP3 10643
Affinity Capture-MS Homo sapiens
49 MRPS10 55173
Affinity Capture-MS Homo sapiens
50 B3GNT2 10678
Affinity Capture-MS Homo sapiens
51 MCM2 4171
Affinity Capture-MS Homo sapiens
52 PABPC4L 132430
Affinity Capture-MS Homo sapiens
53 KLC2 64837
Affinity Capture-MS Homo sapiens
54 WDR74 54663
Affinity Capture-MS Homo sapiens
55 HERC5 51191
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
56 CCDC137  
Affinity Capture-MS Homo sapiens
57 RRP12 23223
Affinity Capture-MS Homo sapiens
58 TERF2IP 54386
Affinity Capture-MS Homo sapiens
59 COPS5 10987
Affinity Capture-MS Homo sapiens
60 FBXW7  
Affinity Capture-MS Homo sapiens
61 PRC1 9055
Affinity Capture-MS Homo sapiens
62 MRPS24 64951
Affinity Capture-MS Homo sapiens
63 SRRM2 23524
Co-fractionation Homo sapiens
64 POU5F1  
Affinity Capture-MS Homo sapiens
65 BRPF3  
Affinity Capture-MS Homo sapiens
66 DNAJC21  
Affinity Capture-MS Homo sapiens
67 WASH1 100287171
Affinity Capture-MS Homo sapiens
68 DNAJB1 3337
Proximity Label-MS Homo sapiens
69 RPLP2 6181
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
70 NSUN4  
Affinity Capture-MS Homo sapiens
71 RPF2 84154
Affinity Capture-MS Homo sapiens
72 TTF1  
Affinity Capture-MS Homo sapiens
73 PAK1IP1  
Affinity Capture-MS Homo sapiens
74 PRKRA 8575
Affinity Capture-MS Homo sapiens
75 DDA1  
Affinity Capture-MS Homo sapiens
76 EED  
Affinity Capture-MS Homo sapiens
77 SRP68 6730
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
78 ANP32A 8125
Co-fractionation Homo sapiens
79 P3H1 64175
Co-fractionation Homo sapiens
80 ATG16L1 55054
Affinity Capture-MS Homo sapiens
81 EIF3B 8662
Co-fractionation Homo sapiens
82 NOC3L 64318
Affinity Capture-MS Homo sapiens
83 MRPS7 51081
Affinity Capture-MS Homo sapiens
84 METTL18  
Affinity Capture-MS Homo sapiens
85 Eif3a 13669
Affinity Capture-MS Mus musculus
86 CUL1 8454
Affinity Capture-MS Homo sapiens
87 MYCN  
Affinity Capture-MS Homo sapiens
88 SAE1 10055
Co-fractionation Homo sapiens
89 RPL19 6143
Co-fractionation Homo sapiens
90 TMEM87A 25963
Affinity Capture-MS Homo sapiens
91 KIF14 9928
Affinity Capture-MS Homo sapiens
92 GAR1 54433
Co-fractionation Homo sapiens
93 FOXP1 27086
Protein-RNA Homo sapiens
94 LIN28A  
Affinity Capture-MS Homo sapiens
95 CASK 8573
Affinity Capture-MS Homo sapiens
96 RPS4Y2 140032
Affinity Capture-MS Homo sapiens
97 MRPS35 60488
Affinity Capture-MS Homo sapiens
98 TRIM41 90933
Affinity Capture-MS Homo sapiens
99 SRP9 6726
Co-crystal Structure Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
100 DPP8 54878
Co-fractionation Homo sapiens
101 ZBTB48  
Affinity Capture-MS Homo sapiens
102 P4HA1 5033
Co-fractionation Homo sapiens
103 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
104 DDX21 9188
Affinity Capture-MS Homo sapiens
105 C18orf25 147339
Affinity Capture-MS Homo sapiens
106 MRPS26 64949
Affinity Capture-MS Homo sapiens
107 DIMT1 27292
Affinity Capture-MS Homo sapiens
108 RBM28 55131
Affinity Capture-MS Homo sapiens
109 PPP6R2 9701
Affinity Capture-MS Homo sapiens
110 RBM19 9904
Affinity Capture-MS Homo sapiens
111 PTCD3 55037
Affinity Capture-MS Homo sapiens
112 TRA2A 29896
Affinity Capture-MS Homo sapiens
113 BLM 641
Affinity Capture-MS Homo sapiens
114 MRPS11  
Affinity Capture-MS Homo sapiens
115 STAU1 6780
Affinity Capture-MS Homo sapiens
116 ACIN1 22985
Co-fractionation Homo sapiens
117 DRICH1  
Affinity Capture-MS Homo sapiens
118 ZNF22  
Affinity Capture-MS Homo sapiens
119 VRK1 7443
Affinity Capture-MS Homo sapiens
120 RPL5 6125
Affinity Capture-MS Homo sapiens
121 PDLIM5 10611
Co-fractionation Homo sapiens
122 DDX10  
Affinity Capture-MS Homo sapiens
123 SNRPD1 6632
Co-fractionation Homo sapiens
124 RPS25 6230
Affinity Capture-MS Homo sapiens
125 RPA2 6118
Proximity Label-MS Homo sapiens
126 DDX5 1655
Co-fractionation Homo sapiens
127 MRPS5 64969
Affinity Capture-MS Homo sapiens
128 VPRBP 9730
Affinity Capture-MS Homo sapiens
129 RAD18  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
130 HUWE1 10075
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
131 RAB3GAP1 22930
Affinity Capture-MS Homo sapiens
132 LYAR 55646
Affinity Capture-MS Homo sapiens
133 COPS3 8533
Affinity Capture-MS Homo sapiens
134 ANAPC4 29945
Affinity Capture-MS Homo sapiens
135 ITGB1BP2  
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
136 GPC1 2817
Affinity Capture-MS Homo sapiens
137 SPANXN2  
Two-hybrid Homo sapiens
138 RRP1B 23076
Affinity Capture-MS Homo sapiens
139 CSPG5 10675
Affinity Capture-MS Homo sapiens
140 PPM1G 5496
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
141 CEBPA  
Protein-peptide Homo sapiens
142 GTPBP4 23560
Affinity Capture-MS Homo sapiens
143 CYLD  
Affinity Capture-MS Homo sapiens
144 PURB 5814
Affinity Capture-MS Homo sapiens
145 IPO9 55705
Co-fractionation Homo sapiens
146 RPF1  
Affinity Capture-MS Homo sapiens
147 RPLP0 6175
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
148 CENPI  
Affinity Capture-MS Homo sapiens
149 ANLN 54443
Affinity Capture-MS Homo sapiens
150 RRP8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
151 SEC63 11231
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
152 DNAJB14  
Proximity Label-MS Homo sapiens
153 MRPS34 65993
Affinity Capture-MS Homo sapiens
154 CYB5B 80777
Co-fractionation Homo sapiens
155 BMS1  
Affinity Capture-MS Homo sapiens
156 GPC4 2239
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
157 PRPF4B 8899
Affinity Capture-MS Homo sapiens
158 HIST1H3A 8350
Cross-Linking-MS (XL-MS) Homo sapiens
159 FANCD2  
Affinity Capture-MS Homo sapiens
160 ABT1 29777
Affinity Capture-MS Homo sapiens
161 KBTBD6  
Affinity Capture-MS Homo sapiens
162 DAP3 7818
Affinity Capture-MS Homo sapiens
163 RPS2 6187
Affinity Capture-MS Homo sapiens
164 PTPN6 5777
Affinity Capture-MS Homo sapiens
165 PCDH1 5097
Affinity Capture-MS Homo sapiens
166 RC3H2  
Affinity Capture-MS Homo sapiens
167 GLE1 2733
Affinity Capture-MS Homo sapiens
168 RPL35 11224
Affinity Capture-MS Homo sapiens
169 ZNF622 90441
Affinity Capture-MS Homo sapiens
170 CALCOCO1 57658
Affinity Capture-MS Homo sapiens
171 MRPS14  
Affinity Capture-MS Homo sapiens
172 CDC16 8881
Affinity Capture-MS Homo sapiens
173 WHSC1 7468
Affinity Capture-MS Homo sapiens
174 CUL3 8452
Affinity Capture-MS Homo sapiens
175 REXO4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
176 MECP2 4204
Affinity Capture-MS Homo sapiens
177 RPL3 6122
Affinity Capture-MS Homo sapiens
178 DNAJC17  
Proximity Label-MS Homo sapiens
179 FGA 2243
Affinity Capture-MS Homo sapiens
180 PAPD5 64282
Affinity Capture-MS Homo sapiens
181 FAM111A 63901
Affinity Capture-MS Homo sapiens
182 NOM1  
Affinity Capture-MS Homo sapiens
183 NACC1 112939
Affinity Capture-MS Homo sapiens
184 DHX37  
Affinity Capture-MS Homo sapiens
185 LARS 51520
Co-fractionation Homo sapiens
186 FN1 2335
Affinity Capture-MS Homo sapiens
187 CLSPN  
Affinity Capture-MS Homo sapiens
188 ZCCHC7  
Affinity Capture-MS Homo sapiens
189 BUD13  
Affinity Capture-MS Homo sapiens
190 ZNF512  
Affinity Capture-MS Homo sapiens
191 EBNA1BP2 10969
Affinity Capture-MS Homo sapiens
192 PRKACA 5566
Proximity Label-MS Homo sapiens
193 DCAF6 55827
Affinity Capture-MS Homo sapiens
194 DDX42 11325
Affinity Capture-MS Homo sapiens
195 IL7R  
Protein-RNA Homo sapiens
196 DKC1 1736
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
197 PRPF19 27339
Co-fractionation Homo sapiens
198 MYC  
Affinity Capture-MS Homo sapiens
199 RPA3 6119
Proximity Label-MS Homo sapiens
200 CEBPZ  
Affinity Capture-MS Homo sapiens
201 PHF6  
Affinity Capture-MS Homo sapiens
202 EGFR 1956
Negative Genetic Homo sapiens
203 NHP2L1 4809
Co-fractionation Homo sapiens
204 PLIN3 10226
Co-fractionation Homo sapiens
205 RPL22 6146
Affinity Capture-MS Homo sapiens
206 HP1BP3 50809
Affinity Capture-MS Homo sapiens
207 CGN  
Co-fractionation Homo sapiens
208 RPLP1 6176
Affinity Capture-MS Homo sapiens
209 DDRGK1 65992
Affinity Capture-MS Homo sapiens
210 BMI1  
Affinity Capture-MS Homo sapiens
211 ZC3HAV1 56829
Affinity Capture-MS Homo sapiens
212 SEPT7 989
Co-fractionation Homo sapiens
213 ZFP62  
Affinity Capture-MS Homo sapiens
214 HIST1H1T 3010
Affinity Capture-MS Homo sapiens
215 RPS15A 6210
Affinity Capture-MS Homo sapiens
216 EEF2K  
Affinity Capture-MS Homo sapiens
217 CLCN2  
Affinity Capture-MS Homo sapiens
218 FTSJ3 117246
Affinity Capture-MS Homo sapiens
219 EIF3M 10480
Affinity Capture-MS Homo sapiens
220 MDM2  
Affinity Capture-MS Homo sapiens
221 PRKDC 5591
Co-fractionation Homo sapiens
222 NGDN  
Affinity Capture-MS Homo sapiens
223 SZRD1 26099
Co-fractionation Homo sapiens
224 NIP7 51388
Affinity Capture-MS Homo sapiens
225 ZNF668  
Affinity Capture-MS Homo sapiens
226 SURF6  
Affinity Capture-MS Homo sapiens
227 EIF3F 8665
Affinity Capture-MS Homo sapiens
228 ASB3 51130
Affinity Capture-MS Homo sapiens
229 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
230 TERF2  
Affinity Capture-MS Homo sapiens
231 SIRT6  
Affinity Capture-MS Homo sapiens
232 WDR4 10785
Co-fractionation Homo sapiens
233 BKRF1  
Affinity Capture-MS
234 NSA2  
Affinity Capture-MS Homo sapiens
235 STK11IP 114790
Affinity Capture-MS Homo sapiens
236 DNAJC19 131118
Proximity Label-MS Homo sapiens
237 RRS1 23212
Affinity Capture-MS Homo sapiens
238 HMGB1 3146
Co-fractionation Homo sapiens
239 RPL6 6128
Co-fractionation Homo sapiens
240 FOLR1 2348
Affinity Capture-MS Homo sapiens
241 PRDM15  
Affinity Capture-MS Homo sapiens
242 PDCD2L 84306
Affinity Capture-MS Homo sapiens
243 ZNF746  
Affinity Capture-MS Homo sapiens
244 EXOSC9 5393
Co-fractionation Homo sapiens
245 MRPS18C  
Affinity Capture-MS Homo sapiens
246 RPS8 6202
Affinity Capture-MS Homo sapiens
247 MRPS31  
Affinity Capture-MS Homo sapiens
248 MEN1 4221
Affinity Capture-MS Homo sapiens
249 BOP1 23246
Affinity Capture-MS Homo sapiens
250 SRP19 6728
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
251 RPS4X 6191
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
252 SQSTM1 8878
Proximity Label-MS Homo sapiens
253 ANAPC1 64682
Affinity Capture-MS Homo sapiens
254 SRP72 6731
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
255 SRP54 6729
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
256 NISCH 11188
Affinity Capture-MS Homo sapiens
257 G3BP2 9908
Affinity Capture-MS Homo sapiens
258 EIF4A3 9775
Co-fractionation Homo sapiens
259 GNL1 2794
Affinity Capture-MS Homo sapiens
260 CENPU  
Affinity Capture-MS Homo sapiens
261 NIFK 84365
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
262 MRPS21  
Affinity Capture-MS Homo sapiens
263 PSMA1 5682
Co-fractionation Homo sapiens
264 ESR1  
Affinity Capture-MS Homo sapiens
265 ANAPC2 29882
Affinity Capture-MS Homo sapiens
266 UFL1 23376
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
267 ZNF317 57693
Affinity Capture-MS Homo sapiens
268 H2AFV 94239
Co-fractionation Homo sapiens
269 NOC2L 26155
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
270 MRPS18B 28973
Affinity Capture-MS Homo sapiens
271 GNL2 29889
Affinity Capture-MS Homo sapiens
272 NCL 4691
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
273 RPS23 6228
Affinity Capture-MS Homo sapiens
274 C16orf72 29035
Affinity Capture-MS Homo sapiens
275 MRPS33  
Affinity Capture-MS Homo sapiens
276 EAF1  
Two-hybrid Homo sapiens
277 UBA2 10054
Co-fractionation Homo sapiens
278 Rrbp1  
Affinity Capture-MS Mus musculus
279 STAU2 27067
Affinity Capture-MS Homo sapiens
280 GLYR1 84656
Affinity Capture-MS Homo sapiens
281 RBM15 64783
Affinity Capture-MS Homo sapiens
282 MIB2 142678
Affinity Capture-MS Homo sapiens
283 KRAS 3845
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
284 ARIH1 25820
Affinity Capture-MS Homo sapiens
285 CHMP4B 128866
Affinity Capture-MS Homo sapiens
286 DDX31  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
287 RPL36AL 6166
Affinity Capture-MS Homo sapiens
288 NVL  
Affinity Capture-MS Homo sapiens
289 SNRPA1 6627
Co-fractionation Homo sapiens
290 TEX10 54881
Affinity Capture-MS Homo sapiens
291 REPIN1  
Affinity Capture-MS Homo sapiens
292 DDX56  
Affinity Capture-MS Homo sapiens
293 MRPS9 64965
Affinity Capture-MS Homo sapiens
294 CDC5L 988
Co-fractionation Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here