Gene description for ATP5J2
Gene name ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2
Gene symbol ATP5J2
Other names/aliases ATP5JL
Species Homo sapiens
 Database cross references - ATP5J2
ExoCarta ExoCarta_9551
Vesiclepedia VP_9551
Entrez Gene 9551
HGNC 848
UniProt P56134  
 ATP5J2 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Mesenchymal stem cells 36408942    
 Gene ontology annotations for ATP5J2
Molecular Function
    proton-transporting ATP synthase activity, rotational mechanism GO:0046933 IBA
    proton-transporting ATP synthase activity, rotational mechanism GO:0046933 IDA
Biological Process
    proton motive force-driven ATP synthesis GO:0015986 NAS
    proton motive force-driven mitochondrial ATP synthesis GO:0042776 IBA
    proton motive force-driven mitochondrial ATP synthesis GO:0042776 IDA
    proton transmembrane transport GO:1902600 NAS
Subcellular Localization
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IC
    mitochondrion GO:0005739 IDA
    mitochondrial inner membrane GO:0005743 NAS
    mitochondrial inner membrane GO:0005743 TAS
    nuclear membrane GO:0031965 IDA
    proton-transporting ATP synthase complex GO:0045259 IBA
    proton-transporting ATP synthase complex GO:0045259 IDA
    proton-transporting ATP synthase complex GO:0045259 NAS
    proton-transporting ATP synthase complex, coupling factor F(o) GO:0045263 IEA
 Experiment description of studies that identified ATP5J2 in sEVs
1
Experiment ID 489
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 488
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for ATP5J2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ATG16L1 55054
Affinity Capture-MS Homo sapiens
2 DUSP19  
Affinity Capture-MS Homo sapiens
3 HYPK 25764
Affinity Capture-MS Homo sapiens
4 RIT1 6016
Negative Genetic Homo sapiens
5 UBE2H 7328
Affinity Capture-MS Homo sapiens
6 MRPS34 65993
Co-fractionation Homo sapiens
7 E2F4  
Affinity Capture-MS Homo sapiens
8 SPRTN  
Affinity Capture-MS Homo sapiens
9 RBM45  
Affinity Capture-MS Homo sapiens
10 RPLP1 6176
Two-hybrid Homo sapiens
11 UQCRQ 27089
Co-fractionation Homo sapiens
12 AMOTL1 154810
Affinity Capture-MS Homo sapiens
13 ATP5J 522
Co-fractionation Homo sapiens
14 OTUD1 220213
Affinity Capture-MS Homo sapiens
15 NR3C1 2908
Proximity Label-MS Homo sapiens
16 ZFPL1 7542
Two-hybrid Homo sapiens
17 ACOT9 23597
Co-fractionation Homo sapiens
18 MRPS28  
Affinity Capture-MS Homo sapiens
19 CHMP4C 92421
Affinity Capture-MS Homo sapiens
20 MME 4311
Affinity Capture-MS Homo sapiens
21 LPP 4026
Two-hybrid Homo sapiens
22 UFL1 23376
Affinity Capture-MS Homo sapiens
23 ATP5A1 498
Co-fractionation Homo sapiens
24 CRELD1 78987
Two-hybrid Homo sapiens
25 COX15 1355
Affinity Capture-MS Homo sapiens
26 SLC25A1 6576
Co-fractionation Homo sapiens
27 EGFR 1956
Negative Genetic Homo sapiens
28 MRPL50 54534
Affinity Capture-MS Homo sapiens
29 PARK2  
Affinity Capture-MS Homo sapiens
30 NDUFA4 4697
Affinity Capture-MS Homo sapiens
31 Ncaph  
Affinity Capture-MS Mus musculus
32 ARMC6 93436
Affinity Capture-MS Homo sapiens
33 ARL8B 55207
Two-hybrid Homo sapiens
34 TUBGCP4 27229
Affinity Capture-MS Homo sapiens
35 NDUFB9 4715
Co-fractionation Homo sapiens
36 ATP5L 10632
Affinity Capture-MS Homo sapiens
37 BLK 640
Affinity Capture-MS Homo sapiens
38 ITGB3BP  
Affinity Capture-MS Homo sapiens
39 KIAA1429 25962
Affinity Capture-MS Homo sapiens
40 PVRL2 5819
Two-hybrid Homo sapiens
41 Ppp2ca 19052
Affinity Capture-MS Mus musculus
42 CAPNS1 826
Two-hybrid Homo sapiens
43 ATP5D 513
Co-fractionation Homo sapiens
44 SLC25A20 788
Co-fractionation Homo sapiens
45 SOAT1 6646
Affinity Capture-MS Homo sapiens
46 TUBA1C 84790
Affinity Capture-MS Homo sapiens
47 MYC  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
48 RPA2 6118
Proximity Label-MS Homo sapiens
49 CNTROB  
Affinity Capture-MS Homo sapiens
50 NEDD1 121441
Affinity Capture-MS Homo sapiens
51 MGST3 4259
Co-fractionation Homo sapiens
52 MCM2 4171
Affinity Capture-MS Homo sapiens
53 FBP1 2203
Two-hybrid Homo sapiens
54 CCDC137  
Two-hybrid Homo sapiens
55 PRPF4 9128
Two-hybrid Homo sapiens
56 NDUFA6  
Two-hybrid Homo sapiens
57 KDM1A 23028
Two-hybrid Homo sapiens
58 OCIAD2 132299
Co-fractionation Homo sapiens
59 RPA4  
Proximity Label-MS Homo sapiens
60 MRPS24 64951
Affinity Capture-MS Homo sapiens
61 PML 5371
Affinity Capture-MS Homo sapiens
62 Cdca5  
Affinity Capture-MS Mus musculus
63 VDAC1 7416
Affinity Capture-MS Homo sapiens
64 VDAC3 7419
Co-fractionation Homo sapiens
65 ATXN3 4287
Affinity Capture-MS Homo sapiens
66 NAF1  
Affinity Capture-MS Homo sapiens
67 TOMM5  
Co-fractionation Homo sapiens
68 RPA3 6119
Proximity Label-MS Homo sapiens
69 Ncstn 59287
Affinity Capture-MS Mus musculus
70 VDAC2 7417
Co-fractionation Homo sapiens
71 HAP1  
Two-hybrid Homo sapiens
72 ATP5B 506
Co-fractionation Homo sapiens
73 DOCK3  
Affinity Capture-MS Homo sapiens
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