Gene description for Pls3
Gene name
plastin 3 (T-isoform)
Gene symbol
Pls3
Other names/aliases
AI115446 AL024105 T-fimbrin
Species
Mus musculus
Database cross references - Pls3
ExoCarta
ExoCarta_102866
Vesiclepedia
VP_102866
Entrez Gene
102866
UniProt
Q99K51
Pls3 identified in sEVs derived from the following tissue/cell type
Colon cancer cells
37309723
T-cell lymphoma cells
37309723
Gene ontology annotations for Pls3
Experiment description of studies that identified Pls3 in sEVs
1
Experiment ID
907
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
37309723
Organism
Mus musculus
Experiment description
Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors
"Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name
Proteomics
Publication year
2023
Sample
Colon cancer cells
Sample name
C26
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
2
Experiment ID
908
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
37309723
Organism
Mus musculus
Experiment description
Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors
"Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name
Proteomics
Publication year
2023
Sample
T-cell lymphoma cells
Sample name
EL4
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
Protein-protein interactions for Pls3
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
Kctd13
Affinity Capture-MS
Mus musculus
2
Stau1
Co-fractionation
Mus musculus
3
Kcna3
Affinity Capture-MS
Mus musculus
4
Eed
Affinity Capture-MS
Mus musculus
5
Usp7
Affinity Capture-MS
Mus musculus
6
Atxn2
20239
Affinity Capture-Western
Mus musculus
7
Slc25a4
11739
Cross-Linking-MS (XL-MS)
Mus musculus
8
Unk
Affinity Capture-RNA
Mus musculus
View the network
image/svg+xml
Pathways in which Pls3 is involved
No pathways found