Gene description for Maob
Gene name monoamine oxidase B
Gene symbol Maob
Other names/aliases 6330414K01Rik
MAO-B
Species Mus musculus
 Database cross references - Maob
ExoCarta ExoCarta_109731
Entrez Gene 109731
UniProt Q8BW75  
 Maob identified in exosomes derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Maob
Molecular Function
    protein homodimerization activity GO:0042803 ISO
    flavin adenine dinucleotide binding GO:0050660 ISO
    oxidoreductase activity GO:0016491 IEA
    primary amine oxidase activity GO:0008131 ISO
Biological Process
    negative regulation of serotonin secretion GO:0014063 ISO
    positive regulation of dopamine metabolic process GO:0045964 ISO
    oxidation-reduction process GO:0055114 ISO
    neurotransmitter catabolic process GO:0042135 ISO
Subcellular Localization
    mitochondrial outer membrane GO:0005741 ISO
    membrane GO:0016020 IEA
    integral component of membrane GO:0016021 IEA
    mitochondrion GO:0005739 ISO
    extracellular exosome GO:0070062 ISO
    mitochondrial inner membrane GO:0005743 IDA
 Experiment description of studies that identified Maob in exosomes
1
Experiment ID 188
ISEV standards
EM
EV Biophysical techniques
GAPDH|UCHL1|HSP90
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Maob
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Maob is involved
PathwayEvidenceSource
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB IEA Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here