Gene description for Ap1g1
Gene name adaptor protein complex AP-1, gamma 1 subunit
Gene symbol Ap1g1
Other names/aliases AA409002
AU041323
AW551707
Adtg
D8Ertd374e
Species Mus musculus
 Database cross references - Ap1g1
ExoCarta ExoCarta_11765
Vesiclepedia VP_11765
Entrez Gene 11765
UniProt P22892  
 Ap1g1 identified in exosomes derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Ap1g1
Molecular Function
    collagen binding GO:0005518 ISO
    protein binding GO:0005515 IPI
    Rab GTPase binding GO:0017137 ISO
    protein transporter activity GO:0008565 IEA
    GTP-dependent protein binding GO:0030742 ISO
    kinesin binding GO:0019894 ISO
    protein C-terminus binding GO:0008022 ISO
Biological Process
    positive regulation of natural killer cell degranulation GO:0043323 ISO
    Golgi to lysosome transport GO:0090160 ISO
    intracellular protein transport GO:0006886 TAS
    transport GO:0006810 IEA
    protein transport GO:0015031 IEA
    positive regulation of natural killer cell mediated cytotoxicity GO:0045954 ISO
    vesicle-mediated transport GO:0016192 TAS
    endosome to melanosome transport GO:0035646 ISO
    microtubule cytoskeleton organization GO:0000226 ISO
Subcellular Localization
    trans-Golgi network GO:0005802 TAS
    clathrin adaptor complex GO:0030131 IEA
    cytoplasm GO:0005737 ISO
    recycling endosome GO:0055037 ISO
    clathrin-coated vesicle GO:0030136 ISO
    membrane coat GO:0030117 IEA
    membrane GO:0016020 ISO
    perinuclear region of cytoplasm GO:0048471 IDA
    cytosol GO:0005829 ISO
    intracellular membrane-bounded organelle GO:0043231 ISO
    microtubule cytoskeleton GO:0015630 ISO
    Golgi apparatus GO:0005794 ISO
    cytoplasmic vesicle GO:0031410 IEA
 Experiment description of studies that identified Ap1g1 in exosomes
1
Experiment ID 907
MISEV standards
✔
EM
EV Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
✔
HSPA5
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
✔
EM
EV Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
✔
HSPA5
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Ap1g1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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