Gene description for Rab14
Gene name RAB14, member RAS oncogene family
Gene symbol Rab14
Other names/aliases 0610030G24Rik
2810475J17Rik
A830021G03Rik
AI314285
AI649155
D030017L14Rik
Species Mus musculus
 Database cross references - Rab14
ExoCarta ExoCarta_68365
Vesiclepedia VP_68365
Entrez Gene 68365
UniProt Q91V41  
 Rab14 identified in exosomes derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Rab14
Molecular Function
    GDP binding GO:0019003 ISO
    myosin V binding GO:0031489 ISO
    glycoprotein binding GO:0001948 ISO
    GTPase activity GO:0003924 ISO
    protein binding GO:0005515 IPI
    nucleotide binding GO:0000166 IEA
    GTP binding GO:0005525 ISO
Biological Process
    protein transport GO:0015031 IEA
    transport GO:0006810 IEA
    regulation of protein localization GO:0032880 ISO
    apical protein localization GO:0045176 ISO
    embryo development GO:0009790 IMP
    fibroblast growth factor receptor signaling pathway GO:0008543 IMP
    Rab protein signal transduction GO:0032482 IBA
    intracellular protein transport GO:0006886 IBA
    Golgi to endosome transport GO:0006895 IMP
    metabolic process GO:0008152 ISO
    small GTPase mediated signal transduction GO:0007264 IEA
    phagolysosome assembly involved in apoptotic cell clearance GO:0090387 IBA
    body fluid secretion GO:0007589 ISO
    endocytic recycling GO:0032456 ISO
Subcellular Localization
    plasma membrane GO:0005886 ISO
    extracellular exosome GO:0070062 ISO
    intracellular GO:0005622 ISO
    cytoplasmic vesicle GO:0031410 IEA
    membrane GO:0016020 IEA
    transport vesicle GO:0030133 ISO
    rough endoplasmic reticulum GO:0005791 ISO
    alveolar lamellar body GO:0097208 ISO
    apical plasma membrane GO:0016324 ISO
    nuclear outer membrane-endoplasmic reticulum membrane network GO:0042175 ISO
    cell GO:0005623 IMP
    Golgi apparatus GO:0005794 IEA
    recycling endosome GO:0055037 ISO
    late endosome GO:0005770 ISO
    endosome GO:0005768 IEA
    Golgi stack GO:0005795 ISO
    intracellular membrane-bounded organelle GO:0043231 ISO
    trans-Golgi network transport vesicle GO:0030140 ISO
    cytosol GO:0005829 ISO
    early endosome GO:0005769 ISO
    perinuclear region of cytoplasm GO:0048471 ISO
    lysosomal membrane GO:0005765 ISO
    phagocytic vesicle GO:0045335 ISO
    lysosome GO:0005764 ISO
    cytoplasm GO:0005737 IMP
 Experiment description of studies that identified Rab14 in exosomes
1
Experiment ID 907
MISEV standards
✔
EM
EV Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
✔
HSPA5
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
✔
EM
EV Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
✔
HSPA5
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Rab14
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SMURF2 64750
Affinity Capture-Luminescence Homo sapiens
View the network image/svg+xml
 Pathways in which Rab14 is involved
PathwayEvidenceSource
Translocation of GLUT4 to the plasma membrane IEA Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here