Gene description for GSTO2
Gene name glutathione S-transferase omega 2
Gene symbol GSTO2
Other names/aliases GSTO 2-2
bA127L20.1
Species Homo sapiens
 Database cross references - GSTO2
ExoCarta ExoCarta_119391
Entrez Gene 119391
HGNC 23064
MIM 612314
UniProt Q9H4Y5  
 GSTO2 identified in exosomes derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for GSTO2
Molecular Function
    glutathione transferase activity GO:0004364 IEA
    protein binding GO:0005515 IPI
    methylarsonate reductase activity GO:0050610 IEA
    glutathione dehydrogenase (ascorbate) activity GO:0045174 IDA
    oxidoreductase activity GO:0016491 IDA
Biological Process
    L-ascorbic acid metabolic process GO:0019852 TAS
    cellular response to arsenic-containing substance GO:0071243 IDA
    oxidation-reduction process GO:0055114 IDA
    glutathione derivative biosynthetic process GO:1901687 TAS
    xenobiotic metabolic process GO:0006805 TAS
    water-soluble vitamin metabolic process GO:0006767 TAS
    small molecule metabolic process GO:0044281 TAS
    vitamin metabolic process GO:0006766 TAS
Subcellular Localization
    extracellular exosome GO:0070062 IDA
    cytosol GO:0005829 TAS
 Experiment description of studies that identified GSTO2 in exosomes
1
Experiment ID 63
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✔
AQP2
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for GSTO2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which GSTO2 is involved
PathwayEvidenceSource
Glutathione conjugation TAS Reactome
Vitamin C (ascorbate) metabolism TAS Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here