Gene description for GSTO2
Gene name glutathione S-transferase omega 2
Gene symbol GSTO2
Other names/aliases GSTO 2-2
bA127L20.1
Species Homo sapiens
 Database cross references - GSTO2
ExoCarta ExoCarta_119391
Vesiclepedia VP_119391
Entrez Gene 119391
HGNC 23064
MIM 612314
UniProt Q9H4Y5  
 GSTO2 identified in exosomes derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for GSTO2
Molecular Function
    glutathione transferase activity GO:0004364 IBA
    protein binding GO:0005515 IPI
    oxidoreductase activity GO:0016491 IDA
    identical protein binding GO:0042802 IPI
    glutathione dehydrogenase (ascorbate) activity GO:0045174 IBA
    glutathione dehydrogenase (ascorbate) activity GO:0045174 IDA
    methylarsonate reductase activity GO:0050610 IEA
Biological Process
    glutathione metabolic process GO:0006749 IBA
    xenobiotic metabolic process GO:0006805 IDA
    L-ascorbic acid metabolic process GO:0019852 IBA
    L-ascorbic acid metabolic process GO:0019852 IDA
    cellular response to arsenic-containing substance GO:0071243 IDA
    cellular oxidant detoxification GO:0098869 IEA
Subcellular Localization
    cytoplasm GO:0005737 IBA
    cytosol GO:0005829 TAS
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified GSTO2 in exosomes
1
Experiment ID 63
MISEV standards
Biophysical techniques
AQP2
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for GSTO2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TFAP2A  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
2 GSTO1 9446
Affinity Capture-MS Homo sapiens
3 GSTO2 119391
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
4 EDRF1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 TXN 7295
Co-fractionation Homo sapiens
6 GPX4 2879
Affinity Capture-MS Homo sapiens
7 C10orf88  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 LIN54  
Affinity Capture-MS Homo sapiens
9 TAGLN2 8407
Co-fractionation Homo sapiens
10 HINT1 3094
Co-fractionation Homo sapiens
11 MUM1  
Two-hybrid Homo sapiens
12 CREBBP  
Two-hybrid Homo sapiens
13 RBM12 10137
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
14 FKBP1A 2280
Co-fractionation Homo sapiens
15 WDR1 9948
Co-fractionation Homo sapiens
16 CNDP2 55748
Co-fractionation Homo sapiens
View the network image/svg+xml



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