Gene description for Bmp1
Gene name bone morphogenetic protein 1
Gene symbol Bmp1
Other names/aliases Pcp
Tld
Species Mus musculus
 Database cross references - Bmp1
ExoCarta ExoCarta_12153
Vesiclepedia VP_12153
Entrez Gene 12153
UniProt P98063  
 Bmp1 identified in exosomes derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Bmp1
Molecular Function
    growth factor activity GO:0008083 IEA
    calcium ion binding GO:0005509 IEA
    cytokine activity GO:0005125 IEA
    zinc ion binding GO:0008270 IEA
    peptidase activity GO:0008233 ISO
    metal ion binding GO:0046872 IEA
    metalloendopeptidase activity GO:0004222 TAS
    hydrolase activity GO:0016787 IEA
    protein binding GO:0005515 IPI
    metallopeptidase activity GO:0008237 IEA
Biological Process
    multicellular organismal development GO:0007275 IEA
    proteolysis GO:0006508 ISO
    cartilage development GO:0051216 IEA
    ossification GO:0001503 IEA
    cell differentiation GO:0030154 IEA
    positive regulation of cartilage development GO:0061036 ISO
Subcellular Localization
    extracellular space GO:0005615 ISO
    membrane-bounded vesicle GO:0031988 ISO
    Golgi apparatus GO:0005794 IEA
    extracellular region GO:0005576 IEA
    proteinaceous extracellular matrix GO:0005578 IEA
 Experiment description of studies that identified Bmp1 in exosomes
1
Experiment ID 907
MISEV standards
✔
EM
EV Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
✔
HSPA5
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
✔
EM
EV Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
✔
HSPA5
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Bmp1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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