Gene description for Casp6
Gene name	caspase 6
Gene symbol	Casp6
Other names/aliases	CASP-6 Mch2
Species	Mus musculus
Database cross references - Casp6
ExoCarta	ExoCarta_12368
Entrez Gene	12368
UniProt	O08738
Casp6 identified in exosomes derived from the following tissue/cell type
Mast cells	17486113

Gene ontology annotations for Casp6

Molecular Function     cysteine-type endopeptidase activity involved in execution phase of apoptosis GO:0097200 IBA     peptidase activity GO:0008233 RCA     cysteine-type peptidase activity GO:0008234 IEA     endopeptidase activity GO:0004175 ISO     cysteine-type endopeptidase activity GO:0004197 IEA     protein binding GO:0005515 IPI     identical protein binding GO:0042802 ISO     hydrolase activity GO:0016787 IEA Biological Process     response to iron ion GO:0010039 ISO     response to hydrogen peroxide GO:0042542 ISO     response to cytokine GO:0034097 ISO     positive regulation of neuron apoptotic process GO:0043525 ISO     proteolysis GO:0006508 RCA     acute inflammatory response to non-antigenic stimulus GO:0002525 ISO     regulation of apoptotic process GO:0042981 RCA     apoptotic process GO:0006915 IBA     response to glucose GO:0009749 ISO     positive regulation of apoptotic process GO:0043065 ISO     execution phase of apoptosis GO:0097194 IBA     positive regulation of retinal cell programmed cell death GO:0046670 ISO Subcellular Localization     nucleus GO:0005634 ISO     cytosol GO:0005829 ISO     nucleoplasm GO:0005654 ISO     cytoplasm GO:0005737 ISO