Gene description for Eno2
Gene name enolase 2, gamma neuronal
Gene symbol Eno2
Other names/aliases AI837106
Species Mus musculus
 Database cross references - Eno2
ExoCarta ExoCarta_13807
Entrez Gene 13807
UniProt P17183  
 Eno2 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Eno2
Molecular Function
    protein heterodimerization activity GO:0046982 ISO
    phosphopyruvate hydratase activity GO:0004634 ISO
    magnesium ion binding GO:0000287 IEA
    metal ion binding GO:0046872 IEA
    lyase activity GO:0016829 IEA
    protein homodimerization activity GO:0042803 ISO
Biological Process
    glycolytic process GO:0006096 IEA
Subcellular Localization
    intracellular GO:0005622 IDA
    myelin sheath GO:0043209 IDA
    neuron projection GO:0043005 ISO
    extracellular exosome GO:0070062 ISO
    neuronal cell body GO:0043025 IDA
    perikaryon GO:0043204 IDA
    phosphopyruvate hydratase complex GO:0000015 IEA
    membrane GO:0016020 IEA
    plasma membrane GO:0005886 IEA
    extracellular space GO:0005615 ISO
    photoreceptor inner segment GO:0001917 IDA
    synaptic membrane GO:0097060 ISO
    cytoplasm GO:0005737 ISO
 Experiment description of studies that identified Eno2 in exosomes
Experiment ID 15
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
Isolation/purification methods Filtration
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
 Protein-protein interactions for Eno2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Eno2 is involved
Gluconeogenesis IEA Reactome
Glycolysis IEA Reactome

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