Gene description for Nploc4
Gene name	nuclear protein localization 4 homolog (S. cerevisiae)
Gene symbol	Nploc4
Other names/aliases	Npl4
Species	Rattus norvegicus
Database cross references - Nploc4
ExoCarta	ExoCarta_140639
Vesiclepedia	VP_140639
Entrez Gene	140639
UniProt	Q9ES54
Nploc4 identified in sEVs derived from the following tissue/cell type
Reticulocytes	21828046

Gene ontology annotations for Nploc4

Molecular Function     protein binding GO:0005515 IPI     ubiquitin protein ligase binding GO:0031625 IBA     ubiquitin protein ligase binding GO:0031625 IDA     K48-linked polyubiquitin modification-dependent protein binding GO:0036435 IDA     ubiquitin binding GO:0043130 IBA     ubiquitin binding GO:0043130 IDA     protein-containing complex binding GO:0044877 IPI     metal ion binding GO:0046872 IEA     ATPase binding GO:0051117 IPI     K63-linked polyubiquitin modification-dependent protein binding GO:0070530 IDA Biological Process     ubiquitin-dependent protein catabolic process GO:0006511 IBA     ubiquitin-dependent protein catabolic process GO:0006511 IEA     ubiquitin-dependent protein catabolic process GO:0006511 ISO     ubiquitin-dependent protein catabolic process GO:0006511 ISS     Golgi organization GO:0007030 IDA     retrograde protein transport, ER to cytosol GO:0030970 EXP     retrograde protein transport, ER to cytosol GO:0030970 IEA     retrograde protein transport, ER to cytosol GO:0030970 ISO     retrograde protein transport, ER to cytosol GO:0030970 ISS     negative regulation of type I interferon production GO:0032480 IEA     negative regulation of type I interferon production GO:0032480 ISO     negative regulation of type I interferon production GO:0032480 ISS     ERAD pathway GO:0036503 IDA     ERAD pathway GO:0036503 ISO     negative regulation of RIG-I signaling pathway GO:0039536 IEA     negative regulation of RIG-I signaling pathway GO:0039536 ISO     negative regulation of RIG-I signaling pathway GO:0039536 ISS     proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161 IEA     membrane fusion GO:0061025 IDA Subcellular Localization     nucleus GO:0005634 IBA     cytosol GO:0005829 IEA     VCP-NPL4-UFD1 AAA ATPase complex GO:0034098 EXP     VCP-NPL4-UFD1 AAA ATPase complex GO:0034098 IDA     VCP-NPL4-UFD1 AAA ATPase complex GO:0034098 IEA     VCP-NPL4-UFD1 AAA ATPase complex GO:0034098 ISO     VCP-NPL4-UFD1 AAA ATPase complex GO:0034098 NAS     UFD1-NPL4 complex GO:0036501 IDA     UFD1-NPL4 complex GO:0036501 IEA     UFD1-NPL4 complex GO:0036501 ISO