Gene description for SYT9
Gene name synaptotagmin IX
Gene symbol SYT9
Other names/aliases -
Species Homo sapiens
 Database cross references - SYT9
ExoCarta ExoCarta_143425
Entrez Gene 143425
HGNC 19265
MIM 613528
UniProt Q86SS6  
 SYT9 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for SYT9
Molecular Function
    calcium ion binding GO:0005509 IBA
    syntaxin binding GO:0019905 IBA
    clathrin binding GO:0030276 IBA
    calcium-dependent phospholipid binding GO:0005544 IBA
    identical protein binding GO:0042802 IEA
Biological Process
    regulation of insulin secretion GO:0050796 IEA
    synaptic vesicle exocytosis GO:0016079 IBA
    regulation of calcium ion-dependent exocytosis GO:0017158 IBA
    positive regulation of calcium ion-dependent exocytosis GO:0045956 IEA
    calcium ion-dependent exocytosis of neurotransmitter GO:0048791 IBA
Subcellular Localization
    plasma membrane GO:0005886 IBA
    integral component of membrane GO:0016021 IEA
    cell junction GO:0030054 IEA
    dense core granule GO:0031045 IEA
    secretory granule membrane GO:0030667 IEA
    synaptic vesicle membrane GO:0030672 IEA
 Experiment description of studies that identified SYT9 in exosomes
Experiment ID 126
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for SYT9
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TRPV1  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
2 TUBB  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
3 CSNK1A1 1452
Co-purification Homo sapiens
4 SNAP25 6616
Invitro Homo sapiens
Affinity Capture-MS Homo sapiens
5 SYNCRIP 10492
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
View the network image/svg+xml
 Pathways in which SYT9 is involved
No pathways found

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