Gene description for RLTPR
Gene name RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
Gene symbol RLTPR
Other names/aliases CARMIL2
CARMIL2b
LRRC16C
Species Homo sapiens
 Database cross references - RLTPR
ExoCarta ExoCarta_146206
Entrez Gene 146206
HGNC 27089
MIM 610859
UniProt Q6F5E8  
 RLTPR identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for RLTPR
Biological Process
    positive regulation of interleukin-2 secretion GO:1900042 IEA
    T cell receptor signaling pathway GO:0050852 IEA
    establishment of protein localization GO:0045184 IEA
    cell migration GO:0016477 IEA
    positive regulation of interferon-gamma secretion GO:1902715 IEA
    positive regulation of T cell proliferation GO:0042102 IEA
    positive regulation of regulatory T cell differentiation GO:0045591 IEA
    maintenance of cell polarity GO:0030011 IEA
    thymus development GO:0048538 IEA
    homeostasis of number of cells GO:0048872 IEA
Subcellular Localization
    F-actin capping protein complex GO:0008290 IEA
    cytoplasm GO:0005737 IEA
    cell-cell junction GO:0005911 IEA
    membrane GO:0016020 IDA
    immunological synapse GO:0001772 IEA
 Experiment description of studies that identified RLTPR in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for RLTPR
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which RLTPR is involved
No pathways found





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