Gene description for BEAN1
Gene name brain expressed, associated with NEDD4, 1
Gene symbol BEAN1
Other names/aliases BEAN
SCA31
Species Homo sapiens
 Database cross references - BEAN1
ExoCarta ExoCarta_146227
Vesiclepedia VP_146227
Entrez Gene 146227
HGNC 24160
MIM 612051
UniProt Q3B7T3  
 BEAN1 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for BEAN1
Subcellular Localization
    membrane GO:0016020 IEA
 Experiment description of studies that identified BEAN1 in exosomes
1
Experiment ID 237
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for BEAN1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 BAG3 9531
Affinity Capture-Luminescence Homo sapiens
2 DDX58 23586
Affinity Capture-RNA Homo sapiens
3 Nedd4 25489
Biochemical Activity Rattus norvegicus
Reconstituted Complex Rattus norvegicus
View the network image/svg+xml
 Pathways in which BEAN1 is involved
No pathways found





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