Gene description for Gstm1
Gene name glutathione S-transferase, mu 1
Gene symbol Gstm1
Other names/aliases Gstb-1
Gstb1
Species Mus musculus
 Database cross references - Gstm1
ExoCarta ExoCarta_14862
Entrez Gene 14862
UniProt P10649  
 Gstm1 identified in exosomes derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Gstm1
Molecular Function
    transferase activity GO:0016740 IEA
    protein binding GO:0005515 IPI
    steroid binding GO:0005496 ISO
    glutathione transferase activity GO:0004364 ISO
    protein heterodimerization activity GO:0046982 IDA
    nickel cation binding GO:0016151 ISO
    protein homodimerization activity GO:0042803 ISO
Biological Process
    cellular response to drug GO:0035690 IDA
    metabolic process GO:0008152 IEA
    glutathione metabolic process GO:0006749 ISO
Subcellular Localization
    extracellular region GO:0005576 ISO
    protein complex GO:0043234 ISO
    myelin sheath GO:0043209 IDA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified Gstm1 in exosomes
1
Experiment ID 188
ISEV standards
✔
EM
EV Biophysical techniques
✔
GAPDH|UCHL1|HSP90
EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Gstm1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 MAP3K5  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
View the network image/svg+xml
 Pathways in which Gstm1 is involved
PathwayEvidenceSource
Glutathione conjugation IEA Reactome





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