Gene description for Hba-a1
Gene name hemoglobin alpha, adult chain 1
Gene symbol Hba-a1
Other names/aliases Hba
Hba1
Hbat1
Species Mus musculus
 Database cross references - Hba-a1
ExoCarta ExoCarta_15122
Entrez Gene 15122
 Hba-a1 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Hba-a1
Molecular Function
    peroxidase activity GO:0004601 ISO
    haptoglobin binding GO:0031720 ISO
Biological Process
    in utero embryonic development GO:0001701 IGI
    erythrocyte development GO:0048821 IGI
Subcellular Localization
    cytosolic small ribosomal subunit GO:0022627 ISO
    haptoglobin-hemoglobin complex GO:0031838 ISO
    blood microparticle GO:0072562 ISO
    membrane GO:0016020 ISO
    extracellular exosome GO:0070062 ISO
    hemoglobin complex GO:0005833 ISO
 Experiment description of studies that identified Hba-a1 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Hba-a1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Hba-a1 is involved
No pathways found





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