Gene description for Krt13
Gene name keratin 13
Gene symbol Krt13
Other names/aliases CK13
K13
Krt-1.13
Krt1-13
Species Mus musculus
 Database cross references - Krt13
ExoCarta ExoCarta_16663
Vesiclepedia VP_16663
Entrez Gene 16663
UniProt P08730  
 Krt13 identified in exosomes derived from the following tissue/cell type
Oligodendrocytes 21136642    
 Gene ontology annotations for Krt13
Molecular Function
    structural molecule activity GO:0005198 IEA
    protein binding GO:0005515 IPI
Biological Process
    cytoskeleton organization GO:0007010 ISO
    epithelial cell differentiation GO:0030855 IBA
    regulation of translation in response to stress GO:0043555 IMP
    tongue morphogenesis GO:0043587 IEA
    intermediate filament organization GO:0045109 IBA
    cellular response to retinoic acid GO:0071300 IEA
Subcellular Localization
    cytoskeleton GO:0005856 IBA
    intermediate filament GO:0005882 IEA
    keratin filament GO:0045095 IBA
    keratin filament GO:0045095 ISO
    intermediate filament cytoskeleton GO:0045111 ISO
    extracellular exosome GO:0070062 ISO
 Experiment description of studies that identified Krt13 in exosomes
1
Experiment ID 33
MISEV standards
✔
EM|IEM
Biophysical techniques
✔
Alix|TSG101
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21136642    
Organism Mus musculus
Experiment description Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons?
Authors "Kramer-Albers EM, Bretz N, Tenzer S, Winterstein C, Mobius W, Berger H, Nave KA, Schild H, Trotter J"
Journal name PROTEOMICS_CL
Publication year 2007
Sample Oligodendrocytes
Sample name Oligodendrocytes
Oli-neu
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.14 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for Krt13
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Zbtb7b  
Affinity Capture-MS Mus musculus
2 Lnx1  
Affinity Capture-MS Mus musculus
3 Nphp4  
Affinity Capture-MS Mus musculus
4 Atxn1  
Affinity Capture-MS Mus musculus
5 Krt4 16682
Co-fractionation Mus musculus
6 Krt7  
Co-fractionation Mus musculus
7 Krt71 56735
Co-fractionation Mus musculus
8 Krt79  
Co-fractionation Mus musculus
9 Fancd2  
Affinity Capture-MS Mus musculus
10 Tgm3  
Co-fractionation Mus musculus
View the network image/svg+xml
 Pathways in which Krt13 is involved
PathwayEvidenceSource
Developmental Biology IEA Reactome
Formation of the cornified envelope IEA Reactome
Keratinization IEA Reactome





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