Gene description for Lamb1
Gene name laminin B1
Gene symbol Lamb1
Other names/aliases C77966
Species Mus musculus
 Database cross references - Lamb1
ExoCarta ExoCarta_16777
Entrez Gene 16777
UniProt P02469  
 Lamb1 identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Lamb1
Molecular Function
    protein binding GO:0005515 IPI
    glycosphingolipid binding GO:0043208 IDA
    enzyme binding GO:0019899 IPI
    integrin binding GO:0005178 IMP
    extracellular matrix structural constituent GO:0005201 ISO
Biological Process
    odontogenesis GO:0042476 ISO
    positive regulation of cell migration GO:0030335 ISO
    embryo implantation GO:0007566 IMP
    neuronal-glial interaction involved in cerebral cortex radial glia guided migration GO:0021812 ISO
    learning or memory GO:0007611 NAS
    neuron projection development GO:0031175 ISO
    negative regulation of cell adhesion GO:0007162 IDA
    substrate adhesion-dependent cell spreading GO:0034446 ISO
    cell migration GO:0016477 IMP
    cell adhesion GO:0007155 IEA
Subcellular Localization
    laminin-10 complex GO:0043259 ISO
    laminin-8 complex GO:0043257 ISO
    laminin-1 complex GO:0005606 ISO
    proteinaceous extracellular matrix GO:0005578 IDA
    laminin complex GO:0043256 IDA
    extracellular space GO:0005615 ISO
    laminin-2 complex GO:0005607 ISO
    basement membrane GO:0005604 ISO
    basal lamina GO:0005605 IDA
    extracellular exosome GO:0070062 ISO
    perinuclear region of cytoplasm GO:0048471 IDA
    extracellular matrix GO:0031012 ISO
    extracellular region GO:0005576 IEA
 Experiment description of studies that identified Lamb1 in exosomes
Experiment ID 210
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Lamb1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.

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