Gene description for Lamc1
Gene name laminin, gamma 1
Gene symbol Lamc1
Other names/aliases Lamb2
Species Mus musculus
 Database cross references - Lamc1
ExoCarta ExoCarta_226519
Entrez Gene 226519
 Lamc1 identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Lamc1
Molecular Function
    glycosphingolipid binding GO:0043208 IDA
    extracellular matrix structural constituent GO:0005201 ISO
    protein binding GO:0005515 IPI
Biological Process
    cell migration GO:0016477 ISO
    hemidesmosome assembly GO:0031581 ISO
    neuron projection development GO:0031175 IDA
    substrate adhesion-dependent cell spreading GO:0034446 ISO
    cell adhesion GO:0007155 ISO
    protein complex assembly GO:0006461 ISO
    extracellular matrix disassembly GO:0022617 ISO
Subcellular Localization
    basal lamina GO:0005605 IDA
    proteinaceous extracellular matrix GO:0005578 ISO
    laminin-1 complex GO:0005606 ISO
    extracellular matrix GO:0031012 ISO
    extracellular exosome GO:0070062 ISO
    basement membrane GO:0005604 ISO
    laminin-10 complex GO:0043259 IPI
    extracellular region GO:0005576 IEA
 Experiment description of studies that identified Lamc1 in exosomes
Experiment ID 210
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Lamc1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Lamc1 is involved
No pathways found

Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here