Gene description for Laptm5
Gene name lysosomal-associated protein transmembrane 5
Gene symbol Laptm5
Other names/aliases E3
Species Mus musculus
 Database cross references - Laptm5
ExoCarta ExoCarta_16792
Entrez Gene 16792
UniProt Q61168  
 Laptm5 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Laptm5
Biological Process
    transport GO:0006810 IEA
Subcellular Localization
    integral component of membrane GO:0016021 IEA
    membrane GO:0016020 IEA
    integral component of plasma membrane GO:0005887 IEA
    lysosomal membrane GO:0005765 IEA
    lysosome GO:0005764 ISO
 Experiment description of studies that identified Laptm5 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Laptm5
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Laptm5 is involved
No pathways found





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