Gene description for Lrp1
Gene name	low density lipoprotein receptor-related protein 1
Gene symbol	Lrp1
Other names/aliases	A2mr AI316852 CD91 Lrp b2b1554Clo
Species	Mus musculus
Database cross references - Lrp1
ExoCarta	ExoCarta_16971
Entrez Gene	16971
UniProt	Q91ZX7
Lrp1 identified in exosomes derived from the following tissue/cell type
Fibroblasts	23260141

Gene ontology annotations for Lrp1

Molecular Function     poly(A) RNA binding GO:0044822 ISO     protein complex binding GO:0032403 ISO     protein binding GO:0005515 IPI     apolipoprotein binding GO:0034185 ISO     protease binding GO:0002020 ISO     calcium ion binding GO:0005509 IDA     metal ion binding GO:0046872 IEA Biological Process     cholesterol metabolic process GO:0008203 IMP     cell proliferation GO:0008283 ISO     receptor-mediated endocytosis GO:0006898 ISO     negative regulation of smooth muscle cell migration GO:0014912 IMP     negative regulation of neuron apoptotic process GO:0043524 ISO     endocytosis GO:0006897 IEA     regulation of phospholipase A2 activity GO:0032429 IMP     apoptotic cell clearance GO:0043277 IMP     multicellular organismal development GO:0007275 IEA     regulation of actin cytoskeleton organization GO:0032956 IMP     regulation of cholesterol transport GO:0032374 IMP     negative regulation of platelet-derived growth factor receptor-beta signaling pathway GO:2000587 IMP     positive regulation of cholesterol efflux GO:0010875 IMP     negative regulation of neuron projection development GO:0010977 ISO     positive regulation of protein transport GO:0051222 ISO     aorta morphogenesis GO:0035909 IMP     positive regulation of lipid transport GO:0032370 IMP     negative regulation of Wnt signaling pathway GO:0030178 IDA     protein kinase C-activating G-protein coupled receptor signaling pathway GO:0007205 ISO     beta-amyloid clearance GO:0097242 IMP Subcellular Localization     perinuclear region of cytoplasm GO:0048471 ISO     dendrite GO:0030425 ISO     neuronal cell body GO:0043025 ISO     focal adhesion GO:0005925 ISO     membrane GO:0016020 IDA     receptor complex GO:0043235 ISO     integral component of membrane GO:0016021 IEA     endosome GO:0005768 ISO     plasma membrane GO:0005886 IEA     coated pit GO:0005905 IEA     integral component of plasma membrane GO:0005887 IDA     clathrin-coated vesicle GO:0030136 ISO     nucleus GO:0005634 IEA     lysosomal membrane GO:0005765 ISO     cytoplasm GO:0005737 ISO     nucleolus GO:0005730 ISO