Gene description for Dock10
Gene name	dedicator of cytokinesis 10
Gene symbol	Dock10
Other names/aliases	9330153B10Rik A630054M16Rik Jr4 Jr5 R75174 ZIZ3 Zizimin3 mKIAA0694
Species	Mus musculus
Database cross references - Dock10
ExoCarta	ExoCarta_210293
Vesiclepedia	VP_210293
Entrez Gene	210293
UniProt	Q8BZN6
Dock10 identified in sEVs derived from the following tissue/cell type
Macrophages	23658846
Macrophages	23658846
Macrophages	23658846
Mast cells	17486113

Gene ontology annotations for Dock10

Molecular Function     guanyl-nucleotide exchange factor activity GO:0005085 IBA     guanyl-nucleotide exchange factor activity GO:0005085 IDA     small GTPase binding GO:0031267 IPI Biological Process     B cell homeostasis GO:0001782 IMP     marginal zone B cell differentiation GO:0002315 IMP     small GTPase-mediated signal transduction GO:0007264 IEA     regulation of cell migration GO:0030334 IBA     regulation of cell migration GO:0030334 IEA     regulation of cell migration GO:0030334 ISO     regulation of Rho protein signal transduction GO:0035023 IBA     positive regulation of GTPase activity GO:0043547 IDA     dendritic spine morphogenesis GO:0060997 IBA     dendritic spine morphogenesis GO:0060997 IMP     regulation of postsynapse assembly GO:0150052 IDA     regulation of postsynapse assembly GO:0150052 IMP Subcellular Localization     nucleus GO:0005634 ISO     nucleus GO:0005634 ISS     nucleoplasm GO:0005654 IEA     nucleoplasm GO:0005654 ISO     cytoplasm GO:0005737 ISO     cytoplasm GO:0005737 ISS     cytosol GO:0005829 IEA     cytosol GO:0005829 ISO     dendritic spine GO:0043197 IDA     postsynapse GO:0098794 IDA     postsynapse GO:0098794 IEP     glutamatergic synapse GO:0098978 IDA     glutamatergic synapse GO:0098978 IEP     glutamatergic synapse GO:0098978 IMP