Gene description for Tdg
Gene name	thymine DNA glycosylase
Gene symbol	Tdg
Other names/aliases	E130317C12Rik JZA-3 Jza1
Species	Mus musculus
Database cross references - Tdg
ExoCarta	ExoCarta_21665
Entrez Gene	21665
UniProt	P56581
Tdg identified in exosomes derived from the following tissue/cell type
Mast cells	17486113

Gene ontology annotations for Tdg

Molecular Function     protein kinase C binding GO:0005080 IPI     protein binding GO:0005515 IPI     hydrolase activity, acting on glycosyl bonds GO:0016798 IEA     SUMO binding GO:0032183 IPI     transcription factor binding GO:0008134 ISO     RNA polymerase II transcription cofactor activity GO:0001104 IGI     pyrimidine-specific mismatch base pair DNA N-glycosylase activity GO:0008263 ISO     DNA N-glycosylase activity GO:0019104 ISO     hydrolase activity GO:0016787 IEA     hydrolase activity, hydrolyzing N-glycosyl compounds GO:0016799 IEA     mismatched DNA binding GO:0030983 ISO     double-stranded DNA binding GO:0003690 ISO     structure-specific DNA binding GO:0043566 IDA     protein homodimerization activity GO:0042803 ISO     protein domain specific binding GO:0019904 ISO Biological Process     mismatch repair GO:0006298 ISO     negative regulation of transcription from RNA polymerase II promoter GO:0000122 ISO     regulation of gene expression, epigenetic GO:0040029 IMP     metabolic process GO:0008152 IEA     base-excision repair GO:0006284 ISO     DNA demethylation GO:0080111 IMP     embryo development GO:0009790 IMP     cellular response to DNA damage stimulus GO:0006974 IEA     regulation of transcription, DNA-templated GO:0006355 IEA     negative regulation of protein binding GO:0032091 IDA     transcription from RNA polymerase II promoter GO:0006366 IGI     chromatin modification GO:0016568 IEA     transcription, DNA-templated GO:0006351 IEA     negative regulation of chromatin binding GO:0035562 IDA     DNA repair GO:0006281 IEA Subcellular Localization     nucleus GO:0005634 ISO     PML body GO:0016605 IDA     nucleoplasm GO:0005654 ISO     plasma membrane GO:0005886 ISO