Gene description for Coq6
Gene name coenzyme Q6 homolog (yeast)
Gene symbol Coq6
Other names/aliases 5930427M12Rik
AW742344
Species Mus musculus
 Database cross references - Coq6
ExoCarta ExoCarta_217707
Entrez Gene 217707
UniProt Q8R1S0  
 Coq6 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Coq6
Molecular Function
    salicylate 5-hydroxylase activity GO:0034785 IEA
    oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen GO:0016709 IEA
    1-hydroxy-2-naphthoate hydroxylase activity GO:0018637 IEA
    phenylacetate hydroxylase activity GO:0018631 IEA
    isobutylamine N-hydroxylase activity GO:0034791 IEA
    molecular_function GO:0003674 ND
    toluene 2-monooxygenase activity GO:0018644 IEA
    tetrahydrofuran hydroxylase activity GO:0018649 IEA
    toluene-sulfonate methyl-monooxygenase activity GO:0018652 IEA
    xylene monooxygenase activity GO:0018639 IEA
    tocotrienol omega-hydroxylase activity GO:0052872 IEA
    toluene-4-sulfonate monooxygenase activity GO:0018651 IEA
    flavin adenine dinucleotide binding GO:0050660 IEA
    4-chlorobenzaldehyde oxidase activity GO:0018471 IEA
    3-(3-hydroxyphenyl)propionate hydroxylase activity GO:0008688 IEA
    6-hydroxynicotinate 3-monooxygenase activity GO:0043731 IEA
    toluene 3-monooxygenase activity GO:0018657 IEA
    4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity GO:0018660 IEA
    oxidoreductase activity GO:0016491 IEA
    bisphenol A hydroxylase A activity GO:0034560 IEA
    dibenzothiophene monooxygenase activity GO:0018640 IEA
    phenanthrene 9,10-monooxygenase activity GO:0018636 IEA
    1-methylnaphthalene hydroxylase activity GO:0034534 IEA
    alpha-pinene monooxygenase [NADH] activity GO:0018634 IEA
    3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity GO:0018653 IEA
    phenanthrene 3,4-monooxygenase activity GO:0018656 IEA
    limonene monooxygenase activity GO:0019113 IEA
    4-nitrophenol 4-monooxygenase activity GO:0018632 IEA
    carbon disulfide oxygenase activity GO:0018643 IEA
    styrene monooxygenase activity GO:0018650 IEA
    2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity GO:0043719 IEA
    monooxygenase activity GO:0004497 IBA
    toluene 4-monooxygenase activity GO:0018638 IEA
    4-hydroxypyridine-3-hydroxylase activity GO:0034894 IEA
    2-methylnaphthalene hydroxylase activity GO:0034526 IEA
    thalianol hydroxylase activity GO:0080014 IEA
    6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity GO:0018641 IEA
    chlorophenol 4-monooxygenase activity GO:0018642 IEA
    dimethyl sulfide monooxygenase activity GO:0018633 IEA
    1-hydroxy-2-oxolimonene 1,2-monooxygenase activity GO:0018646 IEA
    branched-chain dodecylbenzene sulfonate monooxygenase activity GO:0034802 IEA
    2-hydroxy-phenylacetate hydroxylase activity GO:0018654 IEA
    3-HSA hydroxylase activity GO:0034819 IEA
    3,5-xylenol methylhydroxylase activity GO:0018630 IEA
    phenanthrene 1,2-monooxygenase activity GO:0018647 IEA
    2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity GO:0018655 IEA
Biological Process
    oxidation-reduction process GO:0055114 IBA
    ubiquinone biosynthetic process GO:0006744 IBA
    secondary metabolite biosynthetic process GO:0044550 IBA
    metabolic process GO:0008152 IEA
Subcellular Localization
    Golgi apparatus GO:0005794 IEA
    cell projection GO:0042995 IEA
    mitochondrion GO:0005739 ISO
 Experiment description of studies that identified Coq6 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Coq6
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Coq6 is involved
PathwayEvidenceSource
Ubiquinol biosynthesis IEA Reactome





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