Gene description for Larp4b
Gene name La ribonucleoprotein domain family, member 4B
Gene symbol Larp4b
Other names/aliases A630096F19
AI256361
D13Wsu64e
Larp5
Species Mus musculus
 Database cross references - Larp4b
ExoCarta ExoCarta_217980
Entrez Gene 217980
UniProt Q6A0A2  
 Larp4b identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Larp4b
Molecular Function
    poly(A) RNA binding GO:0044822 ISO
    nucleic acid binding GO:0003676 IEA
    RNA binding GO:0003723 IEA
Biological Process
    positive regulation of translation GO:0045727 ISO
    regulation of translation GO:0006417 IEA
Subcellular Localization
    cytosol GO:0005829 ISO
    cytoplasmic stress granule GO:0010494 ISO
    nucleolus GO:0005730 ISO
    polysomal ribosome GO:0042788 ISO
    membrane GO:0016020 ISO
    cytoplasm GO:0005737 ISO
 Experiment description of studies that identified Larp4b in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Larp4b
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Larp4b is involved
No pathways found





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