Gene description for ZCCHC24
Gene name zinc finger, CCHC domain containing 24
Gene symbol ZCCHC24
Other names/aliases C10orf56
Z3CXXC8
Species Homo sapiens
 Database cross references - ZCCHC24
ExoCarta ExoCarta_219654
Entrez Gene 219654
HGNC 26911
UniProt Q8N2G6  
 ZCCHC24 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for ZCCHC24
Molecular Function
    poly(A) RNA binding GO:0044822 IDA
    zinc ion binding GO:0008270 IEA
 Experiment description of studies that identified ZCCHC24 in exosomes
1
Experiment ID 235
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for ZCCHC24
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ZCCHC24 is involved
No pathways found





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