Gene description for Dars
Gene name aspartyl-tRNA synthetase
Gene symbol Dars
Other names/aliases 5730439G15Rik
Species Mus musculus
 Database cross references - Dars
ExoCarta ExoCarta_226414
Entrez Gene 226414
UniProt Q922B2  
 Dars identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Dars
Molecular Function
    aminoacyl-tRNA ligase activity GO:0004812 IEA
    nucleic acid binding GO:0003676 IEA
    poly(A) RNA binding GO:0044822 ISO
    aspartate-tRNA ligase activity GO:0004815 IEA
    ATP binding GO:0005524 IEA
    nucleotide binding GO:0000166 IEA
    ligase activity GO:0016874 IEA
Biological Process
    aspartyl-tRNA aminoacylation GO:0006422 IEA
    tRNA aminoacylation for protein translation GO:0006418 IEA
    translation GO:0006412 IEA
Subcellular Localization
    cytoplasm GO:0005737 ISO
    membrane GO:0016020 ISO
    extracellular exosome GO:0070062 ISO
 Experiment description of studies that identified Dars in exosomes
Experiment ID 210
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Dars
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Dars is involved
No pathways found

Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here