Gene description for ANP32C
Gene name acidic (leucine-rich) nuclear phosphoprotein 32 family, member C
Gene symbol ANP32C
Other names/aliases PP32R1
Species Homo sapiens
 Database cross references - ANP32C
ExoCarta ExoCarta_23520
Vesiclepedia VP_23520
Entrez Gene 23520
HGNC 16675
MIM 606877
UniProt O43423  
 ANP32C identified in sEVs derived from the following tissue/cell type
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
 Gene ontology annotations for ANP32C
Molecular Function
    histone binding GO:0042393 IBA
Biological Process
    nucleocytoplasmic transport GO:0006913 IBA
    regulation of apoptotic process GO:0042981 IBA
Subcellular Localization
    nucleus GO:0005634 IBA
    perinuclear region of cytoplasm GO:0048471 IBA
 Experiment description of studies that identified ANP32C in sEVs
1
Experiment ID 834
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 835
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for ANP32C
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 FOXE1  
Affinity Capture-MS Homo sapiens
2 FOXB1  
Affinity Capture-MS Homo sapiens
3 FOXL2  
Affinity Capture-MS Homo sapiens
4 TRAPPC5 126003
Affinity Capture-MS Homo sapiens
5 PTPN2 5771
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which ANP32C is involved
No pathways found





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