Gene description for ZKSCAN5
Gene name zinc finger with KRAB and SCAN domains 5
Gene symbol ZKSCAN5
Other names/aliases ZFP95
ZNF914
ZSCAN37
Species Homo sapiens
 Database cross references - ZKSCAN5
ExoCarta ExoCarta_23660
Vesiclepedia VP_23660
Entrez Gene 23660
HGNC 12867
MIM 611272
UniProt Q9Y2L8  
 ZKSCAN5 identified in sEVs derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for ZKSCAN5
Molecular Function
    RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IBA
    DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 IBA
    DNA-binding transcription factor activity GO:0003700 NAS
    protein binding GO:0005515 IPI
    zinc ion binding GO:0008270 NAS
Biological Process
    regulation of DNA-templated transcription GO:0006355 NAS
    regulation of transcription by RNA polymerase II GO:0006357 IBA
Subcellular Localization
    nucleus GO:0005634 IBA
    nucleus GO:0005634 NAS
 Experiment description of studies that identified ZKSCAN5 in sEVs
1
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ZKSCAN5
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ZNF232  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 ZSCAN20  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 ZSCAN21  
Affinity Capture-MS Homo sapiens
4 RHOB 388
Reconstituted Complex Homo sapiens
5 SUV39H1  
Two-hybrid Homo sapiens
6 BRD3 8019
Affinity Capture-MS Homo sapiens
7 THOC5 8563
Co-fractionation Homo sapiens
8 ZBTB9  
Two-hybrid Homo sapiens
9 THOC3  
Co-fractionation Homo sapiens
10 TNNT1  
Two-hybrid Homo sapiens
11 ZSCAN1  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which ZKSCAN5 is involved
PathwayEvidenceSource
Gene expression (Transcription) TAS Reactome
Generic Transcription Pathway TAS Reactome
RNA Polymerase II Transcription TAS Reactome





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