Gene description for Itgb1
Gene name	integrin, beta 1
Gene symbol	Itgb1
Other names/aliases	-
Species	Rattus norvegicus
Database cross references - Itgb1
ExoCarta	ExoCarta_24511
Entrez Gene	24511
UniProt	P49134
Itgb1 identified in exosomes derived from the following tissue/cell type
Adipocytes	25998041
Hepatocytes	19367702
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Itgb1

Molecular Function     protein heterodimerization activity GO:0046982 ISO     peptide binding GO:0042277 IDA     alpha-actinin binding GO:0051393 IDA     cell adhesion molecule binding GO:0050839 ISO     protein complex binding GO:0032403 IPI     fibronectin binding GO:0001968 IDA     receptor binding GO:0005102 IPI     glycoprotein binding GO:0001948 IPI     laminin binding GO:0043236 ISO     collagen binding GO:0005518 IDA     protease binding GO:0002020 ISO     protein kinase binding GO:0019901 IPI     protein binding GO:0005515 IPI     protein domain specific binding GO:0019904 IDA     kinase binding GO:0019900 IPI     metal ion binding GO:0046872 IEA     actin binding GO:0003779 ISO     receptor activity GO:0004872 IEA     integrin binding GO:0005178 ISO     collagen binding involved in cell-matrix adhesion GO:0098639 ISO Biological Process     negative regulation of neuron differentiation GO:0045665 IMP     protein transport within lipid bilayer GO:0032594 IMP     cell-cell adhesion mediated by integrin GO:0033631 ISO     in utero embryonic development GO:0001701 ISO     positive regulation of neuron differentiation GO:0045666 IMP     positive regulation of cell proliferation GO:0008284 ISO     negative regulation of cell projection organization GO:0031345 IMP     regulation of cell cycle GO:0051726 ISO     cell-matrix adhesion GO:0007160 ISO     transforming growth factor beta receptor signaling pathway GO:0007179 ISO     regulation of G-protein coupled receptor protein signaling pathway GO:0008277 IMP     response to gonadotropin GO:0034698 IEP     dendrite morphogenesis GO:0048813 ISO     maternal process involved in female pregnancy GO:0060135 IEP     mesodermal cell differentiation GO:0048333 ISO     positive regulation of cell migration GO:0030335 IMP     G1/S transition of mitotic cell cycle GO:0000082 ISO     calcium-independent cell-matrix adhesion GO:0007161 ISO     visual learning GO:0008542 ISO     positive regulation of establishment of protein localization to plasma membrane GO:0090004 ISS     cell migration GO:0016477 ISO     negative regulation of cell differentiation GO:0045596 ISO     cardiac muscle tissue development GO:0048738 ISO     negative regulation of Rho protein signal transduction GO:0035024 ISO     positive regulation of apoptotic process GO:0043065 ISO     sarcomere organization GO:0045214 ISO     tissue homeostasis GO:0001894 IMP     positive regulation of cell-substrate adhesion GO:0010811 IMP     negative regulation of cell proliferation GO:0008285 IMP     stress fiber assembly GO:0043149 ISO     leukocyte cell-cell adhesion GO:0007159 ISO     cell migration involved in sprouting angiogenesis GO:0002042 ISO     regulation of collagen catabolic process GO:0010710 ISS     leukocyte tethering or rolling GO:0050901 ISO     cellular response to vitamin D GO:0071305 IEP     integrin-mediated signaling pathway GO:0007229 ISO     positive regulation of endocytosis GO:0045807 IMP     germ cell migration GO:0008354 ISO     axon extension GO:0048675 ISO     cellular response to ionizing radiation GO:0071479 IEP     neuron projection development GO:0031175 ISO     response to drug GO:0042493 IEP     bicellular tight junction assembly GO:0070830 IMP     response to nutrient levels GO:0031667 IEP     heterotypic cell-cell adhesion GO:0034113 ISO     response to activity GO:0014823 IEP     cardiac muscle cell differentiation GO:0055007 ISO     cellular calcium ion homeostasis GO:0006874 IDA     response to transforming growth factor beta GO:0071559 IEP     cell fate specification GO:0001708 ISO     cellular response to mechanical stimulus GO:0071260 IEP     positive regulation of MAPK cascade GO:0043410 IDA     cell-substrate adhesion GO:0031589 ISO     negative regulation of anoikis GO:2000811 ISO     cell adhesion GO:0007155 IDA     positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 IMP     formation of radial glial scaffolds GO:0021943 ISO     positive regulation of neuron projection development GO:0010976 IMP Subcellular Localization     recycling endosome GO:0055037 IEA     synaptic membrane GO:0097060 ISO     integrin alpha1-beta1 complex GO:0034665 ISO     sarcolemma GO:0042383 ISO     cytoplasmic vesicle GO:0031410 ISO     cytoplasm GO:0005737 ISO     hemidesmosome GO:0030056 IDA     filopodium GO:0030175 ISO     basement membrane GO:0005604 IDA     invadopodium membrane GO:0071438 ISS     integrin complex GO:0008305 IDA     integrin alpha3-beta1 complex GO:0034667 ISO     cell surface GO:0009986 ISO     dendritic spine GO:0043197 ISO     intercalated disc GO:0014704 ISO     neuromuscular junction GO:0031594 ISO     extracellular exosome GO:0070062 ISO     acrosomal vesicle GO:0001669 IDA     myelin sheath abaxonal region GO:0035748 ISO     receptor complex GO:0043235 ISO     adherens junction GO:0005912 IDA     external side of plasma membrane GO:0009897 ISO     synapse GO:0045202 ISO     melanosome GO:0042470 IEA     integrin alpha2-beta1 complex GO:0034666 ISO     perinuclear region of cytoplasm GO:0048471 ISO     focal adhesion GO:0005925 ISO     integrin alpha7-beta1 complex GO:0034677 ISO     integrin alpha9-beta1 complex GO:0034679 IDA     integrin alpha10-beta1 complex GO:0034680 ISO     plasma membrane GO:0005886 TAS     membrane GO:0016020 ISO     membrane raft GO:0045121 ISO     integrin alpha11-beta1 complex GO:0034681 ISO     lamellipodium GO:0030027 IEA     cell-cell junction GO:0005911 IDA     ruffle membrane GO:0032587 ISO