Gene description for KIF26A
Gene name kinesin family member 26A
Gene symbol KIF26A
Other names/aliases -
Species Homo sapiens
 Database cross references - KIF26A
ExoCarta ExoCarta_26153
Entrez Gene 26153
HGNC 20226
MIM 613231
UniProt Q9ULI4  
 KIF26A identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for KIF26A
Molecular Function
    microtubule motor activity GO:0003777 ISS
    ATPase activity GO:0016887 ISS
    microtubule binding GO:0008017 ISS
    ATP binding GO:0005524 IEA
Biological Process
    regulation of cell growth by extracellular stimulus GO:0001560 ISS
    antigen processing and presentation of exogenous peptide antigen via MHC class II GO:0019886 TAS
    metabolic process GO:0008152 IBA
    enteric nervous system development GO:0048484 ISS
    negative regulation of signal transduction GO:0009968 ISS
    blood coagulation GO:0007596 TAS
    microtubule-based movement GO:0007018 TAS
Subcellular Localization
    microtubule GO:0005874 IEA
    kinesin complex GO:0005871 IBA
    cytosol GO:0005829 TAS
 Experiment description of studies that identified KIF26A in exosomes
1
Experiment ID 224
ISEV standards
✔
EM|AFM
EV Biophysical techniques
✔
Alix|TSG101
EV Cytosolic markers
✔
CD63|CD81
EV Membrane markers
✔
GOLGA2
EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for KIF26A
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which KIF26A is involved
PathwayEvidenceSource
Kinesins TAS Reactome
MHC class II antigen presentation TAS Reactome





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