Gene description for Vat1
Gene name vesicle amine transport protein 1 homolog (T californica)
Gene symbol Vat1
Other names/aliases VAT-1
Species Mus musculus
 Database cross references - Vat1
ExoCarta ExoCarta_26949
Entrez Gene 26949
UniProt Q62465  
 Vat1 identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Vat1
Molecular Function
    N-ethylmaleimide reductase activity GO:0008748 IEA
    zinc ion binding GO:0008270 IEA
    oxidoreductase activity GO:0016491 IEA
    reduced coenzyme F420 dehydrogenase activity GO:0043738 IEA
    NADPH:sulfur oxidoreductase activity GO:0043914 IEA
    sulfur oxygenase reductase activity GO:0043826 IEA
    epoxyqueuosine reductase activity GO:0052693 IEA
    malolactic enzyme activity GO:0043883 IEA
Biological Process
    oxidation-reduction process GO:0055114 IEA
    negative regulation of mitochondrial fusion GO:0010637 ISO
Subcellular Localization
    mitochondrion GO:0005739 IEA
    extracellular exosome GO:0070062 ISO
    cytoplasm GO:0005737 IEA
    mitochondrial outer membrane GO:0005741 ISO
    membrane GO:0016020 IEA
 Experiment description of studies that identified Vat1 in exosomes
Experiment ID 210
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Vat1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Vat1 is involved
No pathways found

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