Gene description for IL19
Gene name interleukin 19
Gene symbol IL19
Other names/aliases IL-10C
MDA1
NG.1
ZMDA1
Species Homo sapiens
 Database cross references - IL19
ExoCarta ExoCarta_29949
Vesiclepedia VP_29949
Entrez Gene 29949
HGNC 5990
MIM 605687
UniProt Q9UHD0  
 IL19 identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for IL19
Molecular Function
    cytokine activity GO:0005125 TAS
    protein binding GO:0005515 IPI
Biological Process
    apoptotic process GO:0006915 IEA
    immune response GO:0006955 NAS
    signal transduction GO:0007165 NAS
    negative regulation of low-density lipoprotein particle clearance GO:0010989 IEA
    reactive oxygen species metabolic process GO:0072593 IEA
    negative regulation of extrinsic apoptotic signaling pathway GO:2001237 IEA
    positive regulation of intrinsic apoptotic signaling pathway GO:2001244 IEA
Subcellular Localization
    extracellular region GO:0005576 NAS
    extracellular region GO:0005576 TAS
    extracellular space GO:0005615 IEA
 Experiment description of studies that identified IL19 in sEVs
1
Experiment ID 126
MISEV standards
Biophysical techniques
GAPDH
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Antibody array
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for IL19
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 MECP2 4204
Affinity Capture-MS Homo sapiens
2 ZMPSTE24 10269
Affinity Capture-MS Homo sapiens
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