Gene description for CDIP1
Gene name cell death-inducing p53 target 1
Gene symbol CDIP1
Other names/aliases C16orf5
CDIP
I1
LITAFL
Species Homo sapiens
 Database cross references - CDIP1
ExoCarta ExoCarta_29965
Vesiclepedia VP_29965
Entrez Gene 29965
HGNC 13234
MIM 610503
UniProt Q9H305  
 CDIP1 identified in sEVs derived from the following tissue/cell type
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
 Gene ontology annotations for CDIP1
Molecular Function
    protein binding GO:0005515 IPI
    zinc ion binding GO:0008270 IBA
Biological Process
    intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator GO:0042771 IBA
    intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator GO:0042771 IMP
Subcellular Localization
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    nucleus GO:0005634 NAS
    cytoplasmic side of late endosome membrane GO:0098560 IBA
    cytoplasmic side of late endosome membrane GO:0098560 IDA
    cytoplasmic side of lysosomal membrane GO:0098574 IBA
    cytoplasmic side of lysosomal membrane GO:0098574 IDA
 Experiment description of studies that identified CDIP1 in sEVs
1
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for CDIP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TNIP1 10318
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
2 CCR2  
Two-hybrid Homo sapiens
3 ATXN1 6310
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which CDIP1 is involved
No pathways found





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