Gene description for Mlc-c
Gene name Myosin light chain cytoplasmic
Gene symbol Mlc-c
Other names/aliases CG3201
DmMLC_C
DmelCG3201
MyoII
mlc-c
nmELC
Species Drosophila melanogaster
 Database cross references - Mlc-c
ExoCarta ExoCarta_31474
Entrez Gene 31474
UniProt P54357  
 Mlc-c identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for Mlc-c
Molecular Function
    calcium ion binding GO:0005509 IEA
    protein binding GO:0005515 IPI
    myosin heavy chain binding GO:0032036 IPI
    myosin binding GO:0017022 IPI
Biological Process
    actin filament-based movement GO:0030048 IDA
Subcellular Localization
    unconventional myosin complex GO:0016461 NAS
    myosin II complex GO:0016460 IPI
    myosin VII complex GO:0031477 IPI
    myosin complex GO:0016459 ISS
    myosin VI complex GO:0031476 IPI
    myosin V complex GO:0031475 IPI
 Experiment description of studies that identified Mlc-c in exosomes
1
Experiment ID 202
ISEV standards
IEM
EV Biophysical techniques
TSG10|RAB35
EV Cytosolic markers
FLOT2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP.
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Mlc-c
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Mlc-c is involved
No pathways found





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